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A 4-Hydroxy-1,8-Naphthalimide-Based Turn-on Two-Photon Fluorescent Probe for Hydrogen Polysulfide Sensing

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Journal of Applied Spectroscopy Aims and scope

In order to quantitatively detect hydrogen polysulfides (H2Sn, n > 1) in biosystems, we propose a new two-photon turnon fluorescent probe, named Np–Sn, based on the D–π–A skeleton two-photon fluorophore of 4 -hydroxy-1,8-naphthalimide derivative and deprotection of 2-fluoro-5-nitrobenzoic ester by H2Sn–Np–Sn displayed a more than 80-fold enhancement towards H2Sn in 550 nm and high sensitivity with a detection limit as low as 33 nM. Additionally, the probe Np–Sn was further used for fluorescence imaging of H2Sn in living cells under two-photon excitation (820 nm), which showed a high-resolution imaging, thus demonstrating its practical application in biological systems for the study of physiological and pathological functions of H2Sn.

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References

  1. G. I. Giles, K. M. Tasker, and C. Jacob, Free Rad. Biol. Med., 31, 1279–1283 (2001).

    Article  Google Scholar 

  2. M. C. H. Gruhlke and A. J. Slusarenko, Plant Physiol. Biochem., 59, 98–107 (2012).

    Article  Google Scholar 

  3. P. Nagy and M. T. Ashby, J. Am. Chem. Soc., 129, 14082–14091 (2007).

    Article  Google Scholar 

  4. C. E. Paulsen and K. S. Carroll, Chem. Rev., 113, 4633–4679 (2013).

    Article  Google Scholar 

  5. D. Zhang, I. Macinkovic, N. O. Devarie-Baez, J. Pan, C. M. Park, K. S. Carroll, M. R. Filipovic, and M. Xian, Angew. Chem. Int. Ed., 53, 575–581 (2014).

    Article  Google Scholar 

  6. H. Kimura, Nitric Oxide, 41, 4–10 (2014).

    Article  Google Scholar 

  7. P. Nagy, Z. Pálinkás, A. Nagy, B. Budai, I. Tóth, and A. Vasas, Biochim. Biophys. Acta: Gen. Subjects, 1840, 876–891 (2014).

    Article  Google Scholar 

  8. O. Kabil, N. Motl, and R. Banerjee, Biochim. Biophys. Acta: Proteins Proteomics, 1844, 1355–1366 (2014).

    Article  Google Scholar 

  9. H. Kimura, Neurochem. Int., 63, 492–497 (2013).

    Article  Google Scholar 

  10. R. Greiner, Z. Pálinkás, K. Bäsell, D. Becher, H. Antelmann, P. Nagy, and T. P. Dick, Antioxid. Redox Signal., 19, 1749–1765 (2013).

    Article  Google Scholar 

  11. H. M. Kim and B. R. Cho, Chem. Asian J., 6, 58–69 (2011).

    Article  Google Scholar 

  12. H. M. Kim and B. R. Cho, Acc. Chem. Res., 42, 863–872 (2009).

    Article  Google Scholar 

  13. W. Chen, E. W. Rosser, D. Zhang, W. Shi, Y. Li, W. Dong, H. Ma, D. Hu, and M. Xian, Org. Lett., 17, 2776–2779 (2015).

    Article  Google Scholar 

  14. W. Chen, C. Liu, B. Peng, Y. Zhao, A. Pacheco, and M. Xian, Chem. Sci., 4, 2892–2896 (2013).

    Article  Google Scholar 

  15. W. Chen, E. W. Rosser, T. Matsunaga, A. Pacheco, T. Akaike, and M. Xian, Angew. Chem. Int. Ed., 54, 13961–13965 (2015).

    Article  Google Scholar 

  16. C. Liu, W. Chen, W. Shi, B. Peng, Y. Zhao, H. Ma, and M. Xian, J. Am. Chem. Soc., 136, 7257–7260 (2014).

    Article  Google Scholar 

  17. L. Zeng, S. Chen, T. Xia, W. Hu, C. Li, and Z. Liu, Anal. Chem., 87, 3004–3010 (2015).

    Article  Google Scholar 

  18. Y. Huang, F. Yu, J. Wang, and L. Chen, Anal. Chem., 88, 4122–4129 (2016).

    Article  Google Scholar 

  19. Q. Han, Z. Mou, H. Wang, X. Tang, Z. Dong, L. Wang, X. Dong, and W. Liu, Anal. Chem., 88, 7206–7212 (2016).

    Article  Google Scholar 

  20. J. Zhang, X. Zhu, X. Hu, H. Liu, J. Li, L. Feng, X. Yin, X. Zhang, and W. Tan, Anal. Chem.,88, 11892–11899 (2016).

    Article  Google Scholar 

  21. H. Shang, H. Chen, Y. Tang, R. Guo, and W. Lin, Sensor Actuator B, 230, 773–778 (2016).

    Article  Google Scholar 

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Authors and Affiliations

  1. College of Life Sciences and Chemistry, Hunan University of Technology, 412007, Hunan, China

    L. Zhou & Sh. Hu

  2. College of Food Science and Technology, Central South University of Forestry and Technology, 410004, Hunan, China

    L. Zhou & G. Yuan

  3. Hunan University, State Key Laboratory for Chemo/Biosensing and Chemometrics, 410082, Hunan, China

    L. Zhou

Authors
  1. L. Zhou
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  2. G. Yuan
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  3. Sh. Hu
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Corresponding author

Correspondence to L. Zhou.

Additional information

Published in Zhurnal Prikladnoi Spektroskopii, Vol. 86, No. 6, pp. 962–967, November–December, 2019.

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Zhou, L., Yuan, G. & Hu, S. A 4-Hydroxy-1,8-Naphthalimide-Based Turn-on Two-Photon Fluorescent Probe for Hydrogen Polysulfide Sensing. J Appl Spectrosc 86, 1071–1076 (2020). https://doi.org/10.1007/s10812-020-00942-2

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  • DOI: https://doi.org/10.1007/s10812-020-00942-2

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