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Multifunctional ENY2 Protein Interacts with RNA Helicase MLE

  • BIOCHEMISTRY, BIOPHYSICS, AND MOLECULAR BIOLOGY
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Abstract

ENY2 protein of Drosophila melanogaster was previously discovered and characterized in our laboratory [1, 2]. It was found that ENY2 is a subunit of several multiprotein complexes and connects various stages of gene expression [3–5]. This work is devoted to studying the interaction of ENY2 with RNA helicase MLE. This interaction was confirmed by independent methods. Data indicating that this interaction is conserved in evolution and is important for the functioning of MLE in both sexes were obtained.

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Funding

This study was supported by the Russian Foundation for Basic Research (project no. 18-04-01019) and the program “Postgenomic Technologies and Promising Decisions in Biomedicine.”

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Authors and Affiliations

  1. Institute of Gene Biology, Russian Academy of Sciences, 119334, Moscow, Russia

    J. V. Nikolenko, M. M. Kurshakova & A. N. Krasnov

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  1. J. V. Nikolenko
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  2. M. M. Kurshakova
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  3. A. N. Krasnov
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Correspondence to J. V. Nikolenko.

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Conflict of interests. The authors declare that they have no conflict of interest.

Statement on the welfare of animals. All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.

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Translated by M. Batrukova

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Nikolenko, J.V., Kurshakova, M.M. & Krasnov, A.N. Multifunctional ENY2 Protein Interacts with RNA Helicase MLE. Dokl Biochem Biophys 489, 407–410 (2019). https://doi.org/10.1134/S1607672919060140

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  • DOI: https://doi.org/10.1134/S1607672919060140

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