LRR-ning the Rules: Synapse Organization in the Primary Rod Pathway

doi:10.1016/j.neuron.2020.02.027

Neuron

Volume 105, Issue 6, 18 March 2020, Pages 949-951

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In this issue of Neuron, Sinha et al. (2020) demonstrate that synaptic organization at rod bipolar cell terminals is regulated by a leucine-rich repeat protein, LRRTM4. LRRTM4 is expressed specifically by rod bipolar cells; eliminating it in mouse retina perturbs the organization of synaptic ribbons and impairs the function of inhibitory synapses.

Neuron

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LRR-ning the Rules: Synapse Organization in the Primary Rod Pathway