Issue 12, 2020
From the journal:

Analytical Methods

A novel ratiometric fluorescent probe for the detection of hydrogen peroxide in human gastric carcinoma HGC-27 cells†

Yong Xie,‡a   Zhu Chen,‡c   Linan Hu,c   Hailiang Zhang,b   Pengfei Xu ORCID logo *b  and  Ke Pan ORCID logo *a  

* Corresponding authors

a Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P. R. China

b Institute of Clinical Pharmacy & Pharmacology, Jining First People's Hospital, Jining Medical University, Jining 272000, P. R. China

c Departments of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P. R. China

Abstract

Hydrogen peroxide (H2O2) has been recognized as one of the most significant ROS in human health and disease. In this work, we report a new fluorescent probe JNH-1 for the ratiometric detection of H2O2. The probe JNH-1 showed a highly selective fluorescent response to H2O2 against other interferences of ROS and RNS. In addition, this probe was successfully applied for the monitoring and imaging of H2O2 in living human gastric carcinoma HGC-27 cells.

Graphical abstract: A novel ratiometric fluorescent probe for the detection of hydrogen peroxide in human gastric carcinoma HGC-27 cells

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C9AY02263E
Article type
Communication
Submitted
20 Oct 2019
Accepted
21 Feb 2020
First published
17 Mar 2020

Anal. Methods, 2020,12, 1567-1569

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A novel ratiometric fluorescent probe for the detection of hydrogen peroxide in human gastric carcinoma HGC-27 cells

Y. Xie, Z. Chen, L. Hu, H. Zhang, P. Xu and K. Pan, Anal. Methods, 2020, 12, 1567 DOI: 10.1039/C9AY02263E

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