Abstract
After having established in a previous paper that the synthesis of stoichiometric monochloramine is hazardous due to the high exothermicity of the reaction and the risk of decomposition of the solution from 36 °C, it appeared that the best solution for this synthesis is to use microreactor technology. A series of experiments carried out using a Doehlert experimental design provided access to a mathematical model describing, for an initial fixed composition ratio [NH4+]0/[OCl−]0, the evolution of the yield as a function of temperature, the flow rate of the reagents and the number of sodium hydroxide equivalent. Thus, the optimal conditions for the synthesis of stoichiometric chloramine using microreactor technology were established.
Similar content being viewed by others
References
Le DM, Bougrine AJ, Pasquet V, Delalu H (2019) A new strategy for the synthesis of monomethylhydrazine using the Raschig process. 1. Study of the stability of monochloramine. React Kinet Catal 127(2):757–773
Ehrfeld W, Hessel V, Löwe H (2000) Microreactors—new technology for modern chemistry, 1st edn. Mainz, Wiley, VCH
Hessel V, Hardt S, Löve H (2004) Chemical micro process engineering—fundamentals, modelling and reactions. Mainz, Wiley, VCH
Aubin J, Xuereb C (2008) Microréacteurs pour l’industrie. Base documentaire: Développement de solvants alternatifs et intensification des procédés. Techniques de l’ingénieur. Ref: IN94
Frank T (2008) Microreactors in organic synthesis and catalysis. Wiley, VCH Weinheim
Goupy J (2001) Introduction aux plans d’expériences, 2nd edn. Dunod, Paris
Delalu H, Duriche C, Berthet J, Le Gars P (2006) Process for the synthesis of monochloramine. US Patent 7045659
Goupy J (1999) Plans d’expériences pour surfaces de réponse. Dunod, Paris
Kamoun A, Chaabouni M M, Ayedi H F (2011) Plans d’expériences et traitement de surface—Méthodologie des surfaces de réponses. Base documentaire: Traitements de surface des métaux: contexte et gestion environnementale. Technique de l’ingénieur. Ref: M1429
Dodge Y, Rousson V (2004) Analyse de régression appliquée. Dunod, Paris
Brisset S, Gillon F, Vivier S, Brochet P (2001) Optimization with experimental design: an approach using Taguchi’s methodology and finite element simulations. IEEE Trans Magn 37(5):3530–3533
Lavric ED (2008) Thermal performance of corning glass microstructures. Conference: ECI International Conference on Heat Transfer and Fluid Flow in Microscale. Whistler
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Le, D.M., Bougrine, A.J., Duclos, O. et al. A new strategy for the synthesis of monomethylhydrazine using the Raschig process. 2: Continuous synthesis of stoichiometric monochloramine using the microreactor technology. Reac Kinet Mech Cat 130, 17–34 (2020). https://doi.org/10.1007/s11144-020-01761-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11144-020-01761-4