Comprehensive analysis of CD8+ T cell populations specific to cytomegalovirus reveals that the evolution of the T cell antigen receptor repertoire during chronic infections is characterized by the expansion of low-affinity clones.
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Redeker, A., Arens, R. ‘Reverse evolution’ in T cell biology. Nat Immunol 21, 360–362 (2020). https://doi.org/10.1038/s41590-020-0639-z
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DOI: https://doi.org/10.1038/s41590-020-0639-z