Skip to main content
Log in

Age-related outcomes in laparoscopic hiatal hernia repair: Is there a “too old” for antireflux surgery?

  • 2019 EAES Oral
  • Published:
Surgical Endoscopy Aims and scope Submit manuscript

Abstract

Background

Minimally invasive antireflux surgery has been shown to be safe and effective for the treatment of gastroesophageal reflux (GERD) in elderly patients. However, there is a paucity of data on the influence of advanced age on long-term quality of life (QoL) and perioperative outcomes after laparoscopic antireflux surgery (LARS).

Method

A retrospective study of patients undergoing LARS between February 2012 and June 2018 at a single institution was conducted. Patients were divided into four age categories. Perioperative data and quality of life (QOL) outcomes were collected and analyzed.

Results

A total of 492 patients, with mean follow-up of 21 months post surgery, were included in the final analysis. Patients were divided into four age-determined subgroups (< 50:75, 50–65:179, 65–75:144, ≥ 75:94). Advancing age was associated with increasing likelihood of comorbid disease. Older patients were significantly more likely to require Collis gastroplasty (OR 2.09), or concurrent gastropexy (OR 3.20). Older surgical patients also demonstrated increased operative time (ß 6.29, p < .001), length of hospital stay (ß 0.56, p < .001) in addition to increased likelihood of intraoperative complications (OR 2.94, p = .003) and reoperations (OR 2.36, p < .05). However, postoperative QoL outcomes and complication rates were parallel among all age groups.

Conclusions

Among older patients, there is a greater risk of intraoperative complications, reoperation rates as well as longer operative time and LOS after LARS. However, a long-term QoL benefit is demonstrated among elderly patients who have undergone this procedure. Rather than serving as an exclusion criterion for surgical intervention, advanced age among chronic reflux patients should instead represent a comorbidity addressed in the planning stages of LARS.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Stefanidis D, Hope W, Kohn G, Reardon P, Richardson W, Fanelli R (2010) Guidelines for surgical treatment of gastroesophageal reflux disease. Surg Endosc 24(11):2647–2669. https://doi.org/10.1007/s00464-010-1267-8

    Article  PubMed  Google Scholar 

  2. Becher A, Dent J (2011) Systematic review: ageing and gastro-oesophageal reflux disease symptoms, oesophageal function and reflux oesophagitis. Aliment Pharmacol Ther 33(4):442–454. https://doi.org/10.1111/j.1365-2036.2010.04542.x

    Article  CAS  PubMed  Google Scholar 

  3. Poh CH, Navarro-Rodriguez T, Fass R (2010) Review: treatment of gastroesophageal reflux disease in the elderly. Am J Med 123(6):496–501. https://doi.org/10.1016/j.amjmed.2009.07.036

    Article  PubMed  Google Scholar 

  4. Cowgill SM, Arnaoutakis D, Villadolid D et al (2006) Results after laparoscopic fundoplication: does age matter? Am Surg 72(9):778

    Article  PubMed  Google Scholar 

  5. Beck PE, Watson DI, Devitt PG, Game PA, Jamieson GG (2009) Impact of gender and age on the long-term outcome of laparoscopic fundoplication. World J Surg 33(12):2620–2626. https://doi.org/10.1007/s00268-009-0216-y

    Article  PubMed  Google Scholar 

  6. Johnson DA, Fennerty MB (2004) Heartburn severity underestimates erosive esophagitis severity in elderly patients with gastroesophageal reflux disease. Gastroenterology 126(3):660–664. https://doi.org/10.1053/j.gastro.2003.12.001

    Article  PubMed  Google Scholar 

  7. Fernando HC, Schauer PR, Buenaventura PO, Christie NA, Close JM, Luketich JD (2003) Outcomes of minimally invasive antireflux operations in the elderly: a comparative review. J Soc Laparoendosc Surg 7(4):311–315

    Google Scholar 

  8. Irino T, Takeuchi H, Ozawa S et al (2010) Age and body mass index: significant predictive factors for successful laparoscopic antireflux surgery. Surg Today 40(12):1137–1143. https://doi.org/10.1007/s00595-009-4200-9

    Article  PubMed  Google Scholar 

  9. Brehant O, Pessaux P, Arnaud J et al (2006) Long-term outcome of laparoscopic antireflux surgery in the elderly. J Gastrointest Surg 10(3):439–444. https://doi.org/10.1016/j.gassur.2005.06.017

    Article  PubMed  Google Scholar 

  10. Flum DR, Koepsell T, Heagerty P, Pellegrini CA (2002) The nationwide frequency of major adverse outcomes in antireflux surgery and the role of surgeon experience, 1992–1997. J Am Coll Surg 195(5):611–618. https://doi.org/10.1016/S1072-7515(02)01490-4

    Article  PubMed  Google Scholar 

  11. Weltz AS, Zahiri HR, Sibia US, Wu N, Fantry GT, Park AE (2017) Patients are well served by collis gastroplasty when indicated. Surgery. 162(3):568–576. https://doi.org/10.1016/j.surg.2017.04.005

    Article  PubMed  Google Scholar 

  12. Park AE, Hoogerboord CM, Sutton E (2012) Use of the falciform ligament flap for closure of the esophageal hiatus in giant paraesophageal hernia. J Gastrointest Surg 16(7):1417–1421. https://doi.org/10.1007/s11605-012-1888-4

    Article  PubMed  Google Scholar 

  13. McHorney CA, Robbins J, Lomax K et al (2002) The SWAL–QOL and SWAL–CARE outcomes tool for oropharyngeal dysphagia in adults: III documentation of reliability and validity. Dysphagia 17(2):97–114. https://doi.org/10.1007/s00455-001-0109-1

    Article  PubMed  Google Scholar 

  14. Keefe MA (2006) Validation of a quality-of-life instrument for laryngopharyngeal reflux. Yearb Otolaryngol Head Neck Surg 2006:129–130. https://doi.org/10.1016/S1041-892X(08)70113-6

    Article  Google Scholar 

  15. Velanovich V (2007) The development of the GERD-HRQL symptom severity instrument. Dis Esophagus 20(2):130–134. https://doi.org/10.1111/j.1442-2050.2007.00658.x

    Article  CAS  PubMed  Google Scholar 

  16. Belafsky PC, Postma GN, Koufman JA (2002) Validity and reliability of the reflux symptom index (RSI). J Voice 16(2):274–277. https://doi.org/10.1016/S0892-1997(02)00097-8

    Article  PubMed  Google Scholar 

  17. Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG (2009) Research electronic data capture (REDCap): a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 42(2):377–381. https://doi.org/10.1016/j.jbi.2008.08.010

    Article  PubMed  Google Scholar 

  18. Lin H, Watts JN, Peel NM, Hubbard RE (2016) Frailty and post-operative outcomes in older surgical patients: a systematic review. BMC Geriatr 16(1):157. https://doi.org/10.1186/s12877-016-0329-8

    Article  PubMed  PubMed Central  Google Scholar 

  19. Deiner S, Silverstein JH (2012) Long-term outcomes in elderly surgical patients. Mt Sinai J Med 79(1):95–106. https://doi.org/10.1002/msj.21288

    Article  PubMed  PubMed Central  Google Scholar 

  20. Malani PN (2009) Functional status assessment in the preoperative evaluation of older adults. JAMA 302(14):1582–1583. https://doi.org/10.1001/jama.2009.1453

    Article  CAS  PubMed  Google Scholar 

  21. Gangopadhyay N, Perrone JM, Soper NJ et al (2006) Outcomes of laparoscopic paraesophageal hernia repair in elderly and high-risk patients. Surgery 140(4):491–499. https://doi.org/10.1016/j.surg.2006.07.001

    Article  PubMed  Google Scholar 

  22. Molena D, Mungo B, Stem M, Feinberg RL, Lidor AO (2014) Outcomes of operations for benign foregut disease in elderly patients: a national surgical quality improvement program database analysis. Surgery 156(2):352–360. https://doi.org/10.1016/j.surg.2014.04.005

    Article  PubMed  Google Scholar 

  23. Oor JE, Koetje JH, Roks DJ, Nieuwenhuijs VB, Hazebroek EJ (2016) Laparoscopic hiatal hernia repair in the elderly patient. World J Surg 40(6):1404–1411. https://doi.org/10.1007/s00268-016-3428-y

    Article  CAS  PubMed  Google Scholar 

  24. El Lakis MA, Kaplan SJ, Hubka M, Mohiuddin K, Low DE (2017) The importance of age on short-term outcomes associated with repair of giant paraesophageal hernias. Ann Thorac Surg 103(6):1700–1709. https://doi.org/10.1016/j.athoracsur.2017.01.078

    Article  PubMed  Google Scholar 

  25. Merzlikin OV, Louie BE, Farivar AS, Shultz D, Aye RW (2017) Repair of symptomatic paraesophageal hernias in elderly patients results in sustained quality of life at 5 years and beyond. Surg Endosc 31(10):3979. https://doi.org/10.1007/s00464-017-5432-1

    Article  PubMed  Google Scholar 

  26. Gils Contreras A, Bonada Sanjaume A, Montero Jaime M et al (2018) Effects of two preoperatory weight loss diets on hepatic volume, metabolic parameters, and surgical complications in morbid obese bariatric surgery candidates: a randomized clinical trial. Obes Surg 28(12):3756–3768. https://doi.org/10.1007/s11695-018-3413-7

    Article  CAS  PubMed  Google Scholar 

  27. Makary MA, Segev DL, Peter J, Syin D, Bandeen-Roche K, Patel P, Takenaga R, Devgan L, Holzmueller CG, Tian J, Fried LP (2010) Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg 210(6):901–908. https://doi.org/10.1016/j.jamcollsurg.2010.01.028

    Article  PubMed  Google Scholar 

  28. Polomsky M, Hu R, Sepesi B et al (2010) A population-based analysis of emergent vs elective hospital admissions for an intrathoracic stomach. Surg Endosc 24(6):1250–1255. https://doi.org/10.1007/s00464-009-0755-1

    Article  PubMed  Google Scholar 

  29. Poulose B, Gosen C, Marks J et al (2008) Inpatient mortality analysis of paraesophageal hernia repair in octogenarians. J Gastrointest Surg 12(11):1888–1892. https://doi.org/10.1007/s11605-008-0625-5

    Article  PubMed  Google Scholar 

  30. Bawahab M, Mitchell P, Church N, Debru E (2009) Management of acute paraesophageal hernia. Surg Endosc 23(2):255–259. https://doi.org/10.1007/s00464-008-0190-8

    Article  PubMed  Google Scholar 

  31. Agwunobi AO, Bancewicz J, Attwood SE (1998) Simple laparoscopic gastropexy as the initial treatment of paraoesophageal hiatal hernia. Br J Surg 85(5):604–606

    Article  CAS  PubMed  Google Scholar 

Download references

Funding

No financial support was received for this study.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Adrian Park.

Ethics declarations

Disclosures

Dr. Park, Addo, Zahiri, Sanford, and Mr. Broda have no conflict of interest or financial or relevant financial ties to disclose.

Informed consent

All authors certify that they accept responsibility as an author and have contributed to the concept, data gathering, analysis, manuscript drafting, and give their final approval.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Addo, A., Sanford, Z., Broda, A. et al. Age-related outcomes in laparoscopic hiatal hernia repair: Is there a “too old” for antireflux surgery?. Surg Endosc 35, 429–436 (2021). https://doi.org/10.1007/s00464-020-07489-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00464-020-07489-5

Keywords

Navigation