Correction to: Molecular and Cellular Biochemistry (2016) 413:109–118 https://doi.org/10.1007/s11010-015-2644-3

In the original article, Figs. 3b, 4a, c and 5d were published incorrectly. The correct version of the Figs. (3b, 4a, c and 5d) are provided in this correction.

Fig. 3
figure 3

Galangin inhibited HSFs activation and contractile ability. a, b The levels of α-SMA mRNA and protein were measured after incubation with galangin (5–25 μM) or DMSO for 3 days and c images and quantification of collagen gel contraction assay captured at time 3 days after galangin treatment. Dash lines indicate the areas of collagen gel. Data were presented as the mean ± SD, *p < 0.05; **p< 0.01; ***p < 0.001

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Fig. 4
figure 4

Galangin reduced Smad2/3 phosphorylation by selective targeting ALK5. a Levels of phosphorylated and total Smad2 and Smad3 and total Smad4 were examined by Western blot after HSFs were incubated with 5 to 25 μM galangin or DMSO for 12 h. b Levels of phosphorylated and total Smad2 and Smad3, total Smad4, Smad6, and Smad7 were examined by Western blot after HSFs were incubated with 5–25 μM galangin or DMSO for 12 h. c Western blot analysis of TGF-β1, TGFβRI and TGFβRII in HSFs treated with galangin at different concentrations. d immunofluorescence images in which nuclei are labeled as blue and Smad2/3 as green. Scale bars = 50 μm and e, f effects of galangin on phosphorylation of Smad2 and Smad3 and protein expression of collagen type-I/III and α-SMA in ALK5 siRNA-transfected HSFs and EF-ALK5-transfected HSFs. Data were presented as the mean ± SD, NS not significant; **p < 0.01; ***p < 0.001

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Fig. 5
figure 5

Galangin attenuated hypertrophic scar formation in a mechanical load-induced mouse model. a Images of scars 14-day postincision and gross area quantification at all examined time points. Scale bars = 3 mm, b images of H&E stained sections and crosssection size quantification. The dashed lines outline the scar. Scale bars = 200 μm, c images of Masson Trichrome-stained sections and SEI quantification. ‘‘D’’ represents the thickness of scar while “d”’ represents the thickness of adjacent normal skin. SEI is defined by the D/d ratio. Scale bars = 100 μm. d Picrosirius red staining under polarized light and quantification of collagen density. Scale bars = 20 μm. e, f immunohistochemistry staining of PCNA and α-SMA. Scale bars = 20 μm. Data were presented as the mean ± SD, n = 6/6, ***p < 0.001

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