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Prevalence and frequency of subchondral bone marrow edema in the lumbar facet joints of asymptomatic and symptomatic individuals

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Abstract

Objective

To prospectively compare the prevalence and frequency of subchondral bone marrow edema (BME) in the lumbar facet joints of low back pain patients and healthy subjects.

Materials and methods

Lumbar magnetic resonance imaging (MRI) examinations were performed on 55 asymptomatic participants (18 men; age range 21–63; mean 36 ± 12 years; body mass index (BMI) range 16–31; mean 22.6 ± 3.2 kg/m2) and 79 low back pain patients (36 men; age range 18–77; mean 47 ± 14 years; BMI range 18–40; mean 27.8 ± 4.4 kg/m2). In both groups, facet joint subchondral BME signal was evaluated using T2-weighted STIR imaging, and facet joint osteoarthritis was characterized as mild, moderate, and severe.

Results

The BME signal was found in seven asymptomatic participants (12.7%) and 28 low back pain patients (35.4%) (P = 0.003). A significant portion of the patients (15.2%) presented more than one BME signal (P = 0.011). By pooling the ten facet joints of all subjects in each group, a significant difference in osteoarthritis grade distribution was observed between the two groups (P < 0.001). When adjusted for low back pain status, age, BMI, Modic type 1, disk herniation, and facet joint osteoarthritis maximal grade, only the latter was significantly associated with the facet joint BME signal (P < 0.001).

Conclusion

Despite the higher prevalence and frequency of the BME signal in facet joints of low back pain patients compared to that in healthy subjects, the signal was found to be associated with the severity of the patients’ osteoarthritis and not with their low back pain status.

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Authors and Affiliations

  1. Department of Radiology, Centre Hospitalier Universitaire Ambroise Paré, Mons, Belgium

    Afarine Madani, Raphaël Katz & Carine Neugroschl

  2. Department of Radiology, Hôpital Erasme, Université Libre de Bruxelles, 808 Route de Lennik, 1070, Brussels, Belgium

    Afarine Madani & Pierre Alain Gevenois

  3. Department of Chest Medicine, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium

    Alain Van Muylem

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  1. Afarine Madani
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  2. Raphaël Katz
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Correspondence to Afarine Madani.

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Madani, A., Katz, R., Muylem, A.V. et al. Prevalence and frequency of subchondral bone marrow edema in the lumbar facet joints of asymptomatic and symptomatic individuals. Skeletal Radiol 49, 1141–1147 (2020). https://doi.org/10.1007/s00256-020-03400-4

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