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Metal-free visible-light-mediated organophotoredox catalysis: synthesis of 3-functionalized indole via C–C, C–N bond formation

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Abstract

A visible-light-mediated, mild and one-pot three-component reaction in the presence of organophotoredox catalyst Eosin Y using EtOH:H2O as reaction medium for the synthesis of 3-functionalized indole derivatives was developed. Visible light used in the protocol is green, inexpensive, readily available energy source. The sustainable reagents make the protocol compatible with green chemistry demands.

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Acknowledgements

The authors gratefully acknowledge SAIF, Punjab University Chandigarh for providing all the spectroscopic and analytical data. M.D. Ansari acknowledges CSTUP (Project sanction letter No. CST/D- 2276) for the financial support. N. Yadav, S. Tiwari and Vijay B. Yadav are grateful to CSIR, New Delhi for the Senior Research Fellowship (SRF). Ankit Verma and Saif Ansari acknowledge UGC, New Delhi for the Junior Research Fellowship (JRF).

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Authors and Affiliations

  1. Laboratory of Green Synthesis, Department of Chemistry, University of Allahabad, Allahabad, 211002, India

    Neetu Yadav, Mohd Danish Ansari, Vijay B. Yadav, Ankit Verma, Saurabh K. Tiwari, Saif Ansari & I. R. Siddiqui

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  1. Neetu Yadav
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  2. Mohd Danish Ansari
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  3. Vijay B. Yadav
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  7. I. R. Siddiqui
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Correspondence to I. R. Siddiqui.

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Yadav, N., Ansari, M.D., Yadav, V.B. et al. Metal-free visible-light-mediated organophotoredox catalysis: synthesis of 3-functionalized indole via C–C, C–N bond formation. Mol Divers 25, 1103–1109 (2021). https://doi.org/10.1007/s11030-020-10044-y

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