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Disseminated Pneumocystis jirovecii Infection with Osteomyelitis in a Patient with CTLA-4 Haploinsufficiency

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References

  1. Cohen OJ, Stoeckle MY. Extrapulmonary Pneumocystis carinii infections in the acquired immunodeficiency syndrome. Arch Intern Med. 1991;151(6):1205–14.

    Article  CAS  Google Scholar 

  2. Kuehn HS, Ouyang W, Lo B, Deenick EK, Niemela JE, Avery DT, et al. Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4. Science. 2014;345(6204):1623–7.

    Article  CAS  Google Scholar 

  3. Schubert D, Bode C, Kenefeck R, Hou TZ, Wing JB, Kennedy A, et al. Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations. Nat Med. 2014;20(12):1410–6.

    Article  CAS  Google Scholar 

  4. Schwab C, Gabrysch A, Olbrich P, Patino V, Warnatz K, Wolff D, et al. Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects. J Allergy Clin Immunol. 2018;142(6):1932–46.

    Article  CAS  Google Scholar 

  5. Yarmohammadi H, Cunningham-Rundles C. Idiopathic CD4 lymphocytopenia: pathogenesis, etiologies, clinical presentations and treatment strategies. Ann Allergy Asthma Immunol. 2017;119(4):374.

    Article  Google Scholar 

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Acknowledgements

We would like to thank Roshini S. Abraham, Ph.D., Lisa Hoyte, N.P., and Sandra Sandoval, M.A., for their invaluable help.

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Correspondence to Yael Gernez.

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Siddiqi, A.E., Liu, A.Y., Charville, G.W. et al. Disseminated Pneumocystis jirovecii Infection with Osteomyelitis in a Patient with CTLA-4 Haploinsufficiency. J Clin Immunol 40, 412–414 (2020). https://doi.org/10.1007/s10875-020-00748-z

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  • DOI: https://doi.org/10.1007/s10875-020-00748-z

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