Neuron
Volume 105, Issue 5, 4 March 2020, Pages 761-763
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What Makes the Human Brain Human?

https://doi.org/10.1016/j.neuron.2020.02.007Get rights and content
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Which elements of the genome endow human brains with the capacity for heightened cognitive abilities? In this issue of Neuron, Namba et al. (2020) find that ARHGAP11B, a human-specific gene, augments cerebral cortex expansion by regulating metabolic pathways in mitochondria.

Keywords

neocortex
basal progenitors
adenine nucleotide translocase
mitochondrial permeability transition pore
tricarboxylic acid cycle
energy metabolism
proliferation

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