Journal of Molecular Biology
Volume 432, Issue 9, 17 April 2020, Pages 2949-2972
ReviewProbing Surfaces in Dynamic Protein Interactions
Under a Creative Commons license
open access
Graphical abstract
Abbreviations
c-Myc
cellular myelocytomatosis oncogene
EM
electron microscopy
Gd-DTPA-BMA
gadolinium-diethylenetriamine pentaacetic acid‐bismethylamide
eIF4E
eukaryotic initiation factor 4E
IDP
intrinsically disordered proteins
IDR
intrinsically disordered regions
LLPS
liquid–liquid phase separation
NAC
non-Abeta component
NOEs
nuclear Overhauser effect
PPIs
protein–protein interactions
PRE
paramagnetic relaxation enhancement
PTMs
post-translational modifications
RDCs
residual dipolar couplings
SERF1
a member of the modifier of aggregation-4/small EDRK-rich factor (MOAG-4/SERF) family
sPRE
solvent paramagnetic relaxation enhancement
Keywords
solvent paramagnetic relaxation enhancement
intrinsically disordered proteins
protein–protein interactions
fuzzy complexes
liquid–liquid phase separation
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© 2020 The Author(s). Published by Elsevier Ltd.