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CELLULAR TRAFFICKING

Rendezvous of Retro-2 at the ER

Nature Chemical Biology volume 16, pages 229–230 (2020)Cite this article

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Retro-2 is a drug that protects cells against bacterial and plant toxins by arresting their trafficking in endosomes. New data show that the target for Retro-2 is surprisingly not within the endosomal system, but on the endoplasmic reticulum.

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Fig. 1: The newly identified mode of action of Retro2.

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Authors and Affiliations

  1. Institute of Basic Medical Sciences, Department of Molecular Medicine, University of Oslo, Oslo, Norway

    Hesso Farhan

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  1. Hesso Farhan
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Correspondence to Hesso Farhan.

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The author declares no competing interests.

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Farhan, H. Rendezvous of Retro-2 at the ER. Nat Chem Biol 16, 229–230 (2020). https://doi.org/10.1038/s41589-020-0475-3

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