No clear consensus exists for managing biochemically recurrent prostate cancer after prostatectomy. Interpretation of new data from the JCOG0401 trial warrants consideration of imaging techniques, prostate-specific antigen (PSA) levels at time of salvage radiotherapy (SRT), use of SRT ± salvage androgen deprivation therapy based on PSA levels, and the interval to biochemical failure.
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AUA guidelines: https://www.auanet.org/guidelines/prostate-cancer-adjuvant-and-salvage-radiotherapy-guideline
EAU guidelines: https://uroweb.org/guideline/prostate-cancer/
NCCN guidelines: https://www.nccn.org/professionals/physician_gls/pdf/prostate.pdf
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Zaorsky, N.G., Kishan, A.U. Salvage therapy at biochemical recurrence of prostate cancer. Nat Rev Urol 17, 195–196 (2020). https://doi.org/10.1038/s41585-020-0290-3
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DOI: https://doi.org/10.1038/s41585-020-0290-3
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RETRACTED ARTICLE: MAGE-C2/CT10 promotes growth and metastasis through upregulating c-Myc expression in prostate cancer
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