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Ion recognition and fluorescent imaging of conjugated polymer fluorescent probes for Fe(III)

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Abstract

Novel polymer fluorescent probes for Fe(III) were synthesized to achieve a steady combination of ferric ions. In the Schiff base reaction of probes’ synthetic process, o-, m- and p-phenylenediamine were respectively introduced to result in a series of new conjugated polymer fluorescent probes. Analyses on optical properties of the probes and probe-Fe(III) characteristic recognition through FS showed an application of the conjugated probes in quantitative identification and detection of Fe(III) with quick responses. Fluorescent imaging of the probes and probe-Fe(III) in living cells in vitro revealed low toxicity of the probes and predicted the probes’ further application for instant \(\text {Fe}^{{3+}}\) detection in clinical diagnosis and dynamic tracing of \(\text {Fe}^{{3+}}\) in biological systems.

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Acknowledgements

This project was supported by Xi’an Medical University Research Fund (2017GJFY04, 2018PT67), Shaanxi Natural Science Basic Research Project (2017JQ8042, 2019JQ-068) and National Natural Science Foundation of China (81702955).

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  1. Contributed equally

Authors and Affiliations

  1. School of Pharmacy, Xi’an Medical University, Xi’an, 710021, Shaanxi, People’s Republic of China

    Lei Zheng, Zhao Cheng, Hao HE & Fei Liang

  2. School of Basic Medical Sciences, Xi’an Medical University, Xi’an, 710021, Shaanxi, People’s Republic of China

    Hao Xu & Long Pang

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  1. Lei Zheng
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  2. Zhao Cheng
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  3. Hao HE
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  4. Hao Xu
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Correspondence to Zhao Cheng.

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Zheng, L., Cheng, Z., HE, H. et al. Ion recognition and fluorescent imaging of conjugated polymer fluorescent probes for Fe(III). Bull Mater Sci 43, 69 (2020). https://doi.org/10.1007/s12034-019-2029-4

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  • DOI: https://doi.org/10.1007/s12034-019-2029-4

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