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Improved therapeutic consistency and efficacy of mesenchymal stem cells expanded with chemically defined medium for systemic lupus erythematosus

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Acknowledgements

This work was supported by the Natural Science Foundation of Shenzhen (JCYJ20180305163407913 and KQJSCX20180328093434771), Guangdong Provincial Science and Technology Program (No. 2019B030301009) and the Medical Foundation of Guangdong (A2018308).

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J.X. designed and supervised the project, interpreted the data, and wrote the manuscript; W.L. conducted the cell culture experiments; H.W. and X.W. conducted the animal studies; J.C., L.Y. and X.Z. collected the clinical samples and conducted the animal studies; and L.L. and Z.H. analyzed the data and corrected the manuscript.

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Correspondence to Jianyong Xu.

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The authors declare no competing interests.

Ethics

This study was approved by the ethics committee of Shenzhen University and followed the tenets of the Declaration of Helsinki.

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Informed consent was obtained from participants prior to study participation.

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Xu, J., Lian, W., Wu, H. et al. Improved therapeutic consistency and efficacy of mesenchymal stem cells expanded with chemically defined medium for systemic lupus erythematosus. Cell Mol Immunol 17, 1104–1106 (2020). https://doi.org/10.1038/s41423-020-0364-4

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