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Magnesium Silicate Bioceramics for Bone Regeneration: A Review

  • Review Article
  • Published:
Journal of the Indian Institute of Science Aims and scope

Abstract

With the increase in need of ideal bone graft materials, magnesium silicate has been explored as resorbable bioceramics. Calcium phosphate-based bioceramics are well studied and being implemented for several orthopaedic applications as they mimic the chemistry of the natural bone. Although extensively used, these materials do not satisfy all the essential requirements of an ideal temporary bone replacement material. Materials, such as tricalcium phosphate (TCP) and hydroxyapatite (HA), have low solubility and often the resorption rate is quite slow when implanted in vivo. The research on magnesium silicate for bone regenerative application is quite relatively young and a new area compared to traditional calcium phosphate-based materials. Although limited research findings have been reported, it is believed that magnesium silicate-based bioceramics may be an alternative to calcium phosphate for bone tissue engineering applications. Thus in this review, we have highlighted the importance of magnesium silicate bioceramics and compared with existing calcium phosphate ceramics. We have also analysed the future directions and the need for clinical implementations.

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Acknowledgements

M.R. would like to acknowledge the financial assistance from Science and Engineering Research Board (SERB-SB/FTP/ETA-0114/2014), Department of Science and Technology (DST), India. S.K.N. would like to acknowledge the support from the Honourable Vice Chancellor, West Bengal University of Animal and Fishery Sciences, Kolkata.

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Authors and Affiliations

  1. Department of Metallurgical and Materials Engineering, Indian Institute of Technology, Kharagpur, Kharagpur, 721302, India

    K. Bavya Devi & Mangal Roy

  2. Department of Veterinary Surgery and Radiology, West Bengal University of Animal and Fishery Sciences, Kolkata, 700037, India

    Samit Kumar Nandi

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  1. K. Bavya Devi
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Correspondence to Samit Kumar Nandi or Mangal Roy.

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Bavya Devi, K., Nandi, S.K. & Roy, M. Magnesium Silicate Bioceramics for Bone Regeneration: A Review. J Indian Inst Sci 99, 261–288 (2019). https://doi.org/10.1007/s41745-019-00119-7

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