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Paediatric spondylodiscitis: a 10-year single institution experience in management and clinical outcomes

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Abstract

Purpose

Discitis in the paediatric population poses diagnostic challenges due to non-specific presenting symptoms and difficulty with expressing pain in non-communicating children. Discitis remains a relatively rare condition in the paediatric population and previous reports are limited to small cohorts. In this article, we report our experience in management of discitis over a 10-year period and review the literature on this topic.

Methods

We retrospectively reviewed cases of paediatric discitis/spondylodiscitis over a 10-year period between 2008 and 2018 managed in our regional paediatric neurosurgery unit. Relevant demographic information, microbiological data, blood investigation profile, antibiotic treatment duration and clinical outcomes were interrogated from clinical notes and electronic databases and further analysed.

Results

Overall, 21 cases of paediatric discitis were identified from year 2008 to 2018 with a female to male ratio of 1.3:1. The mean age at presentation was 4.3 years (range 1 to 15 years). Overall, there were 19 cases of lumbosacral/lumbar, 1 thoracic and 1 cervical discitis. The mean duration of follow-up was 20 months (range 6 to 69 months). The most common presenting features were back pain and refusal to walk/sit or weight bear. Erythrocyte sedimentation rate (ESR) was found to be more sensitive than C-reactive protein (CRP) (sensitivity 78% versus 38%) in our cohort. Computer tomography (CT)-guided biopsy was performed in five cases and only one of these was positive (20%). All patients were treated with intravenous antibiotics with resolution of discitis.

Conclusions

Presentation of discitis in children can be non-specific and requires high index of suspicion. CT-guided biopsy in our cohort revealed a low rate of positive cultures. Despite negative blood cultures and CT-guided biopsy results, empirical intravenous antibiotics were effective in treating discitis successfully. In our cohort, low yield of CT-guided biopsy does not support its use on each case and this may be reserved for cases resistant to antimicrobial therapy or concerns regarding other pathology mimicking infection. Better understanding and awareness of this condition and its pathophysiology can lead to timely imaging, diagnosis and treatment.

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Authors and Affiliations

  1. Department of Neurosurgery, Birmingham Children’s Hospital, Birmingham, B4 6NH, UK

    Fardad T. Afshari, Desiderio Rodrigues, Mahesh Bhat, Guirish A Solanki, A Richard Walsh & William B. Lo

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  1. Fardad T. Afshari
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  2. Desiderio Rodrigues
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  3. Mahesh Bhat
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  4. Guirish A Solanki
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  5. A Richard Walsh
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Correspondence to Fardad T. Afshari.

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Afshari, F.T., Rodrigues, D., Bhat, M. et al. Paediatric spondylodiscitis: a 10-year single institution experience in management and clinical outcomes. Childs Nerv Syst 36, 1049–1054 (2020). https://doi.org/10.1007/s00381-019-04470-z

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  • DOI: https://doi.org/10.1007/s00381-019-04470-z

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