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Enhanced bactericidal action and dye degradation of spicy roots’ extract-incorporated fine-tuned metal oxide nanoparticles

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Abstract

Nanoparticles fabricated with biological reducing agents to minimize toxic effects of chemicals are being focused worldwide. Biologically synthesized metal oxide nanomaterials have become integral part of nanotechnology. The current work is providing an insight on ZnO nanoparticles having root extract of Z. officinale and A. sativum in terms of catalytic and antimicrobial action potential. The synthesized nanoparticles were characterized by X-ray Diffraction (XRD), Fourier-Transform Infrared Spectroscopy (FTIR), X-ray Photoelectron Spectroscopy (XPS), Ultra-Violet visible spectroscopy (UV–vis), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Energy-Dispersive X-ray Spectroscopy (EDS) analysis. The synthesized nanoparticles showed strong absorption at 365 nm with size range between 31.64 and 44 nm for Z. officinale and 28–45 nm in case of A. sativum-doped ZnO as revealed by UV–vis and XRD. The Z. officinale-doped nanoparticles demonstrated enhanced antibacterial activity against multiple drug-resistant S. aureus at increasing concentrations (0.5, 1.0 mg/50 µl) and also actively degraded methylene blue (MB) dye. ZnO nanoparticles synthesized by green approach have potential to resolve emerging drug resistance against pathogenic bacterial diseases. Conclusively, significant inhibition zones resulted against (MDR) S. aureus ranging 1.80–2.25 mm and 2.3–3 mm at low and high concentrations for Z. officinale while, 1.7–2.05 mm and 2.2–2.7 mm for A. sativum-doped ZnO-NPs.

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Acknowledgements

Authors are thankful to Higher Education Commission for financial supports via SRGP-21-1669 and CAS-TWAS President’s Fellowship for international PhD students China.

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Authors and Affiliations

  1. Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore, 54000, Punjab, Pakistan

    A. Haider, M. Ijaz & J. A. Khan

  2. State Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Centre for Soft Matter Science and Engineering, Beijing Engineering Center for Hierarchical Catalysts, Beijing University of Chemical Technology, Beijing, 100029, China

    M. Imran

  3. Department of Chemistry, Government College University, Lahore, 54000, Punjab, Pakistan

    M. Naz

  4. Department of Food Sciences, Cholistan University of Veterinary and Animal Sciences, Near DHA663100, Bahawalpur, Pakistan

    H. Majeed

  5. Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, 54000, Punjab, Pakistan

    M. M. Ali

  6. Solar Cell Applications Research Lab, Department of Physics, Government College University, Lahore, 54000, Punjab, Pakistan

    M. Ikram

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  1. A. Haider
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  2. M. Ijaz
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  3. M. Imran
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  4. M. Naz
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Haider, A., Ijaz, M., Imran, M. et al. Enhanced bactericidal action and dye degradation of spicy roots’ extract-incorporated fine-tuned metal oxide nanoparticles. Appl Nanosci 10, 1095–1104 (2020). https://doi.org/10.1007/s13204-019-01188-x

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  • DOI: https://doi.org/10.1007/s13204-019-01188-x

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