Abstract
To explore the impact of the number of hospital beds on the prevention and control of an infectious disease, a diffusive SIS epidemic model in a heterogeneous environment is proposed and investigated. A nonlinear recovery rate is introduced to describe the effects of the number of hospital beds on the transmission dynamics of the disease. The basic reproduction number, which depends on the number of hospital beds and spatial heterogeneity, is defined. It is shown that a sufficient number of hospital beds is very important for disease control and eradication. The numerical simulations are presented to confirm our theoretical results.
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Abdelrazec, A., Belair, J., Shan, C.H., Zhu, H.P.: Modeling the spread and control of dengue with limited public health resources. Math. Biosci. 271, 136–145 (2016)
Allen, L.J.S., Bolker, B.M., Lou, Y., Nevai, A.L.: Asymptotic profiles of the steady states for an SIS epidemic reaction-diffusion model. Discrete Contin. Dyn. Syst., Ser. A 21, 1–20 (2008)
Boaden, R., Proudlove, N., Wilson, M.: An exploratory study of bed management. J. Manag. Med. 13, 234–250 (1999)
Cantrell, R.S., Cosner, C.: Spatial Ecology Via Reaction-Diffusion Equations. Wiley, New York (2003)
Diekmann, O., Heesterbeek, J.A.P.: Mathematical Epidemiology of Infectious Diseases. Wiley Series in Mathematical and Computational Biology. Wiley, West Sussex (2000)
van den Driessche, P., Watmough, J.: Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission. Math. Biosci. 180, 29–48 (2002)
Ge, J., Kim, K.I., Lin, Z.G., Zhu, H.P.: A SIS reaction-diffusion-advection model in a low-risk and high-risk domain. J. Differ. Equ. 259, 5486–5509 (2015)
Hess, P.: Periodic-Parabolic Boundary Value Problems and Positivity. Pitman Research Notes in Mathematics, vol. 247. Longman, Harlow (1991)
Huang, W., Han, M., Liu, K.: Dynamics of an SIS reaction-diffusion epidemic model for disease transmission. Math. Biosci. Eng. 7, 51–66 (2010)
Kim, K.I., Lin, Z.G.: Asymptotic behavior of an SEI epidemic model with diffusion. Math. Comput. Model. 47, 1314–1322 (2008)
Li, Y., Li, W.T., Yang, Y.R.: Stability of traveling waves of a diffusive susceptible-infective-removed (SIR) epidemic model. J. Math. Phys. 57, 041504 (2016). 28 pp
Li, H.C., Peng, R., Wang, F.B.: Varying total population enhances disease persistence: qualitative analysis on a diffusive SIS epidemic model. J. Differ. Equ. 262, 885–913 (2017)
Lin, Z.G., Zhu, H.P.: Spatial spreading model and dynamics of West Nile virus in birds and mosquitoes with free boundary. J. Math. Biol. 75, 1381–1409 (2017)
Pucci, P., Serrin, J.: The strong maximum principle revisited. J. Differ. Equ. 196, 1–66 (2004)
Protter, M.H., Weinberger, H.F.: Maximum Principles in Differential Equations. Springer, New York (1984)
Peng, R., Yi, F.Q.: Asymptotic profile of the positive steady state for an SIS epidemic reaction-diffusion model: effects of epidemic risk and population movement. Physica D 259, 8–25 (2013)
Peng, R., Zhao, X.Q.: A reaction-diffusion SIS epidemic model in a time-periodic environment. Nonlinearity 25, 1451–1471 (2012)
Shan, C.H., Zhu, H.P.: Bifurcations and complex dynamics of an SIR model with the impact of the number of hospital beds. J. Differ. Equ. 257, 1662–1688 (2014)
Samsuzzoha, M., Singh, M., Lucy, D.: Numerical study of a diffusive epidemic model of influenza with variable transmission coefficient. Appl. Math. Model. 35, 5507–5523 (2011)
Wang, W., Zhao, X.Q.: Basic reproduction numbers for reaction-diffusion epidemic models. SIAM J. Appl. Dyn. Syst. 11, 1652–1673 (2012)
Wu, Y.X., Zou, X.F.: Asymptotic profiles of steady states for a diffusive SIS epidemic model with mass action infection mechanism. J. Differ. Equ. 261, 4424–4447 (2016)
Zhang, X., Liu, X.N.: Backward bifurcation and global dynamics of an SIS epidemic model with general incidence rate and treatment. Nonlinear Anal., Real World Appl. 10, 565–567 (2009)
World Health Organization: World Health Statistics 2005–2011. http://www.who.int/gho/publications/world_health_statistics/en/
World Health Organization: Management of health facilities: Hospitals. http://www.who.int/management/facility/hospital/en/index6.html
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The authors would like to thank the anonymous reviewers for their valuable comments and suggestions that helped improve the quality of this manuscript.
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The work is partially supported by the NNSF of China (Grant No. 11771381, 11701206), Graduate Research and Innovation Projects of Jiangsu Province and Yangzhou University International Academic Exchange Fund.
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Zhang, M., Ge, J. & Lin, Z. The Impact of the Number of Hospital Beds and Spatial Heterogeneity on an SIS Epidemic Model. Acta Appl Math 167, 59–73 (2020). https://doi.org/10.1007/s10440-019-00268-y
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DOI: https://doi.org/10.1007/s10440-019-00268-y
Keywords
- Diffusive SIS model
- Basic reproduction number
- Heterogeneous environment
- Nonlinear recovery rate
- Hospital beds