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Numerical simulation of hemodynamic interactions of red blood cells in microcapillary flow

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Abstract

The hemodynamic interactions of red blood cells (RBCs) in a microcapillary flow are investigated in this paper. This kind of interaction is considered as the non-contact mutual interaction of cells, which is important in the suspension flow of blood, but not sufficiently understood. The distributed Lagrange multiplier/fictitious domain method in the lattice Boltzmann framework is used to solve the suspension of the RBCs. The modification of the flow due to the cells, the dependence of the cell deformation on the flow and the cell-cell interaction via the fluid are discussed. It is revealed that the long-range hydrodynamic interaction with a long interacting distance, more than about 5 times of the RBC equivalent radius, mainly has effect on the rheology properties of the suspension, such as the mean velocity, and the short-range interaction is sensitive to the shape of the cell in the microcapillary flow. The flow velocity around the cell plays a key role in the cell deformation. In the current configuration of the flow and cells, the cells repel each other along the capillary.

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Authors and Affiliations

  1. School of Aeronautics and Aerospace, Zhejiang University, Hangzhou, 310027, China

    Xing Shi  (石兴), Shuai Zhang  (张帅) & Shuang-lian Wang  (王双连)

Authors
  1. Xing Shi  (石兴)
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  2. Shuai Zhang  (张帅)
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  3. Shuang-lian Wang  (王双连)
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Corresponding author

Correspondence to Shuai Zhang  (张帅).

Additional information

Project supported by the National Natural Science Foundation of China (Grant Nos. 11372278, 10902098), the Fundamental Research Funds of the Central Universities (Grant No. 2010QNA40107).

Biography: SHI Xing (1975-), Male, Ph. D., Associate Professor

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Shi, X., Zhang, S. & Wang, Sl. Numerical simulation of hemodynamic interactions of red blood cells in microcapillary flow. J Hydrodyn 26, 178–186 (2014). https://doi.org/10.1016/S1001-6058(14)60020-2

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  • DOI: https://doi.org/10.1016/S1001-6058(14)60020-2

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