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Impact of ascending aorta replacement by graft on elastic properties of descending thoracic aorta evaluated by cardiac magnetic resonance imaging

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Abstract

Objective

The aim of our study was to evaluate the impact of aortic root replacement by graft on the elastic properties of the descending thoracic aorta using cardiac magnetic resonance imaging (MRI) and automatic post-processing.

Materials and methods

Nineteen patients were operated for an aortic root aneurysm. Cardiac MRI was performed before and after surgery to measure aortic compliance. Images were acquired on a 1.5 T MRI with a conventional aortic MRI protocol plus one additional kinetic sequence orientated perpendicularly to the aorta at the level of pulmonary trunk. The contours of the ascending and descending aortas were detected automatically for each phase with homemade software.

Results

Mean time between surgical procedure and earliest post-operative MRI was 18.2 ± 7.1 months. There was no significant difference between the pre- and earliest post-operative mean descending aorta areas and no significant modification in descending aortic compliance after aortic root replacement (1.43 ± 0.84 vs 1.37 ± 0.58 mm2/mmHg, p = 0.47). Pre- and post-operative systolic and diastolic blood pressure were similar. There was a significant decrease in ascending aortic compliance after surgery (2.52 ± 1.24 vs 0.91 ± 0.52 mm2/mmHg; p < 0.0001).

Discussion

The aortic root replacement by graft was not associated with changes in elastic properties of the descending aorta at short term.

Clinical registration number

NCT03817008.

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References

  1. Tai NR, Salacinski HJ, Edwards A, Hamilton G, Seifalian AM (2000) Compliance properties of conduits used in vascular reconstruction. Br J Surg 87(11):1516–1524

    Article  CAS  Google Scholar 

  2. Robicsek F, Thubrikar MJ (2003) Compliance of aortic root conduit. Ann Thorac Surg 75(6):2007 (author reply 2007)

    Article  Google Scholar 

  3. Spadaccio C, Rainer A, Barbato R, Chello M, Meyns B (2013) The fate of large-diameter Dacron® vascular grafts in surgical practice: are we really satisfied? Int J Cardiol 168(5):5028–5029

    Article  Google Scholar 

  4. Bauernschmitt R, Schulz S, Schwarzhaupt A, Kiencke U, Vahl CF, Lange R et al (1999) Simulation of arterial hemodynamics after partial prosthetic replacement of the aorta. Ann Thorac Surg 67(3):676–682

    Article  CAS  Google Scholar 

  5. Spadaccio C, Nappi F, Al-Attar N, Sutherland FW, Acar C, Nenna A et al (2016) Old myths, new concerns: the long-term effects of ascending aorta replacement with Dacron grafts. Not all that glitters is gold. J Cardiovasc Transl Res 9(4):334–342

    Article  Google Scholar 

  6. Leuprecht A, Perktold K, Prosi M, Berk T, Trubel W, Schima H (2002) Numerical study of hemodynamics and wall mechanics in distal end-to-side anastomoses of bypass grafts. J Biomech 35(2):225–236

    Article  Google Scholar 

  7. Morita S, Asou T, Kuboyama I, Harasawa Y, Sunagawa K, Yasui H (2002) Inelastic vascular prosthesis for proximal aorta increases pulsatile arterial load and causes left ventricular hypertrophy in dogs. J Thorac Cardiovasc Surg 124(4):768–774

    Article  Google Scholar 

  8. Fokin AA, Robicsek F, Cook JW, Thubrikar MJ, Schaper J (2004) Morphological changes of the aortic valve leaflets in non-compliant aortic roots: in-vivo experiments. J Heart Valve Dis 13(3):444–451

    PubMed  Google Scholar 

  9. Semaan E, Markl M, Malaisrie SC, Barker A, Allen B, McCarthy P et al (2014) Haemodynamic outcome at four-dimensional flow magnetic resonance imaging following valve-sparing aortic root replacement with tricuspid and bicuspid valve morphology. Eur J Cardio Thorac Surg 45(5):818–825

    Article  Google Scholar 

  10. Lalande A, Khau van Kien P, Salvé N, Ben Salem D, Legrand L, Walker PM et al (2002) Automatic determination of aortic compliance with cine-magnetic resonance imaging: an application of fuzzy logic theory. Invest Radiol 37(12):685–691

    Article  Google Scholar 

  11. Westenberg JJM, van Poelgeest EP, Steendijk P, Grotenhuis HB, Jukema JW, de Roos A (2012) Bramwell–Hill modeling for local aortic pulse wave velocity estimation: a validation study with velocity-encoded cardiovascular magnetic resonance and invasive pressure assessment. J Cardiovasc Magn Reson 14:2

    Article  Google Scholar 

  12. Laffon E, Marthan R, Montaudon M, Latrabe V, Laurent F, Ducassou D (2005) Feasibility of aortic pulse pressure and pressure wave velocity MRI measurement in young adults. J Magn Reson Imaging 21(1):53–58

    Article  Google Scholar 

  13. Grotenhuis HB, Westenberg JJM, Steendijk P, van der Geest RJ, Ottenkamp J, Bax JJ et al (2009) Validation and reproducibility of aortic pulse wave velocity as assessed with velocity-encoded MRI. J Magn Reson Imaging 30(3):521–526

    Article  Google Scholar 

  14. Suever JD, Oshinski J, Rojas-Campos E, Huneycutt D, Cardarelli F, Stillman AE et al (2012) Reproducibility of pulse wave velocity measurements with phase contrast magnetic resonance and applanation tonometry. Int J Cardiovasc Imaging 28(5):1141–1146

    Article  Google Scholar 

  15. Mitéran J, Bouchot O, Cochet A, Lalande A (2018) Automatic determination of aortic compliance based on MRI and adapted curvilinear detector. Biomed Signal Process Control 40:295–311

    Article  Google Scholar 

  16. O’Rourke MF, Staessen JA, Vlachopoulos C, Duprez D, Plante GE (2002) Clinical applications of arterial stiffness; definitions and reference values. Am J Hypertens 15(5):426–444

    Article  Google Scholar 

  17. Monti L, Mauri G, Balzarini L, Tarelli G, Brambilla G, Vitali E et al (2011) Compliance of the Valsalva graft’s pseudosinuses at midterm follow-up with cardiovascular magnetic resonance. Ann Thorac Surg 91(1):92–96

    Article  Google Scholar 

  18. Schoenhoff FS, Loupatatzis C, Immer FF, Stoupis C, Carrel TP, Eckstein FS (2009) The role of the sinuses of Valsalva in aortic root flow dynamics and aortic root surgery: evaluation by magnetic resonance imaging. J Heart Valve Dis 18(4):380–385

    PubMed  Google Scholar 

  19. Ohyama Y, Teixido-Tura G, Ambale-Venkatesh B, Noda C, Chugh AR, Liu C-Y et al (2016) Ten-year longitudinal change in aortic stiffness assessed by cardiac MRI in the second half of the human lifespan: the multi-ethnic study of atherosclerosis. Eur Heart J Cardiovasc Imaging 17(9):1044–1053

    Article  Google Scholar 

  20. Redheuil A, Yu W-C, Wu CO, Mousseaux E, de Cesare A, Yan R et al (2010) Reduced ascending aortic strain and distensibility: earliest manifestations of vascular aging in humans. Hypertens Dallas Tex 1979 55(2):319–326

    CAS  Google Scholar 

  21. Donato Aquaro G, Ait-Ali L, Basso ML, Lombardi M, Pingitore A, Festa P (2011) Elastic properties of aortic wall in patients with bicuspid aortic valve by magnetic resonance imaging. Am J Cardiol 108(1):81–87

    Article  Google Scholar 

  22. Eichhorn JG, Krissak R, Rüdiger H-J, Ley S, Arnold R, Boese J et al (2007) Compliance of the normal-sized aorta in adolescents with Marfan syndrome: comparison of MR measurements of aortic distensibility and pulse wave velocity. ROFO Fortschr Geb Rontgenstr Nuklearmed 179(8):841–846

    Article  CAS  Google Scholar 

  23. Zhu L, Vranckx R, Khau van Kien P, Lalande A, Boisset N, Mathieu F et al (2006) Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus. Nat Genet 38(3):343–349

    Article  CAS  Google Scholar 

  24. Dupont A-C, Poussel M, Hossu G, Marie P-Y, Chenuel B, Felblinger J et al (2017) Aortic compliance variation in long male distance triathletes: a new insight into the athlete’s artery? J Sci Med Sport 20(6):539–542

    Article  Google Scholar 

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Acknowledgements

We would like to thank Suzanne Rankin and Paul-Michael Walker from the Dijon University Hospital for proofreading and editing the manuscript. We would like to thank also Pr Alain Bernard from the Dijon University Hospital for his statistical supporting.

Funding

No funding was received for this work.

Author information

Authors and Affiliations

  1. Department of Cardio-Vascular and Thoracic Surgery, Dijon University Hospital, 14 Rue Gaffarel, 21000, Dijon, France

    Marie-Catherine Morgant, Aline Laubriet & Olivier Bouchot

  2. Le2i Laboratory, University of Burgundy, Dijon, France

    Marie-Catherine Morgant, Johel Miteran, Siyu Lin, Alexandre Cochet, Alain Lalande & Olivier Bouchot

  3. Department of MRI, Dijon University Hospital, Dijon, France

    Alexandre Cochet & Alain Lalande

Authors
  1. Marie-Catherine Morgant
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  2. Johel Miteran
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  3. Siyu Lin
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  4. Aline Laubriet
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  5. Alexandre Cochet
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  6. Alain Lalande
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  7. Olivier Bouchot
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Corresponding author

Correspondence to Marie-Catherine Morgant.

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Conflict of interest

Pr O. Bouchot is a consultant for Edwards Lifescience, Livanova and Abbott.

Ethical standards

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study is recorded on ClinicalTrials.gov with the clinical registration number: NCT03817008.

Informed consent

For this type of study, formal consent is not required. An oral informed consent was obtained from all individual participants included in the study.

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Morgant, MC., Miteran, J., Lin, S. et al. Impact of ascending aorta replacement by graft on elastic properties of descending thoracic aorta evaluated by cardiac magnetic resonance imaging. Magn Reson Mater Phy 33, 641–647 (2020). https://doi.org/10.1007/s10334-020-00829-5

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  • DOI: https://doi.org/10.1007/s10334-020-00829-5

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