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Levothyroxine treatment and cholesterol in hypothyroidism

Thyroid status and serum cholesterol levels are intimately linked. Hypothyroidism causes hypercholesterolaemia, which is thought to be resolved after treatment with levothyroxine and normalization of thyroid-stimulating hormone. However, some studies indicate that hypercholesterolaemia persists despite treatment, requiring more frequent use of statins.

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Correspondence to Peter Taylor.

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Bianco, A.C., Taylor, P. Levothyroxine treatment and cholesterol in hypothyroidism. Nat Rev Endocrinol 16, 193–194 (2020). https://doi.org/10.1038/s41574-020-0323-2

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