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CELL MIGRATION

Bringing order to the matrix

Aligned anisotropic organization of the extracellular matrix by fibroblasts has now been shown to depend on cell reorientation following collision, with the cell collision guidance dependent on the transcription factor, TFAP2C.

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Fig. 1: Anisotropy of the ECM and collision guidance.

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Correspondence to Paolo P. Provenzano.

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Provenzano, P.P. Bringing order to the matrix. Nat. Mater. 19, 130–131 (2020). https://doi.org/10.1038/s41563-019-0592-0

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