Aligned anisotropic organization of the extracellular matrix by fibroblasts has now been shown to depend on cell reorientation following collision, with the cell collision guidance dependent on the transcription factor, TFAP2C.
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Provenzano, P.P. Bringing order to the matrix. Nat. Mater. 19, 130–131 (2020). https://doi.org/10.1038/s41563-019-0592-0
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DOI: https://doi.org/10.1038/s41563-019-0592-0