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Health-related quality of life (HRQoL) associated with echinococcosis patients in Tibetan communities in Shiqu County, China: a case–control study

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Abstract

Purpose

Echinococcosis is a chronic neglected zoonotic disease with high endemic in western China. The aim of the study was to evaluate the Health-related Quality of Life (HRQoL) in patients with echinococcosis in Tibetan communities for investigating the physical and mental health challenges faced by the echinococcosis patients and meeting community health needs.

Methods

The HRQoL was measured with 36-Item Short Form Health Survey (SF-36) questionnaire in the case–control study. Analysis of variance (ANOVA) method was used to analyze the data.

Results

50 echinococcosis patients were collected in study group and divided into three subgroups by the duration of staying on albendazole tablets. 52 healthy individuals were collected in control group. In physical quality of life, the duration of staying on albendazole tables influenced the PF (F = 6.661, P < 0.001), RP (F = 3.130, P = 0.029), and GH (F = 4.105, P = 0.008). In mental quality of life, the duration of staying on albendazole tables influenced the SF (F = 10.764, P < 0.001) and RE (F = 5.573, P = 0.001). The income level was the important confounder in PF (F = 11.515, P = 0.001), GH (F = 10.315, P = 0.002), VT (F = 5.984, P = 0.016), and MH (F = 5.565, P = 0.020).

Conclusions

The HRQoL in people with echinococcosis is reduced in comparison with the healthy individuals. It is necessary to shorten the duration of treatment and adopt the special methods adapting the local culture to improve the health-related quality of life in Tibetan communities. Meanwhile, the economic improvement is the foundation.

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Availability of data and materials

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgments

We thank Shiqu County People’s Hospital and the local health workers for assistance in data collections.

Funding

This study was supported by the Science and Technology Project of Health Planning Committee of Sichuan (18PJ576).

Author information

Author notes

  1. Xuzheng Shan, Yun Chen and Kaicheng Liu contributed equally to this work.

Authors and Affiliations

  1. Prevention and Health Section, Affiliated Hospital, Chengdu University, Chengdu, Sichuan, China

    Xuzheng Shan, Kaicheng Liu, Ruihong Song, Yongqin Wang, Yu Wang, Yi Qing, Shiyun Li & Hongbin Zhang

  2. Xichang Satellite Launch Center, Liangshan, Sichuan, China

    Yun Chen

  3. Shiqu County People’s Hospital, Garze Tibetan Autonomous Prefecture, Sichuan, China

    Sui Zhang, Jun Yu, Jie Yin & Lang Kaji

  4. Social Security Department, China Railway Chengdu Bureau Group Co., Ltd, Chengdu, Sichuan, China

    Ze Yang

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  1. Xuzheng Shan
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Contributions

ZY and SL supervised the study and helped revise drafts of the manuscript. XS conceived, designed the study and collected the data, finalized the analysis, and wrote the drafts of the manuscript. KL and HZ designed the study, wrote the drafts of the manuscript, and interpreted the findings. SZ, JY, JY, LK, RS, YW, YW, and YQ collected the data and analyzed the data. All authors read and approved the final manuscript.

Corresponding authors

Correspondence to Ze Yang or Hongbin Zhang.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of Ethics Committee of Affiliated Hospital, Chengdu University and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Shan, X., Chen, Y., Liu, K. et al. Health-related quality of life (HRQoL) associated with echinococcosis patients in Tibetan communities in Shiqu County, China: a case–control study. Qual Life Res 29, 1559–1565 (2020). https://doi.org/10.1007/s11136-020-02424-6

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