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A two-dimensional zinc(II)-based metal-organic framework for fluorometric determination of ascorbic acid, chloramphenicol and ceftriaxone

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Abstract

A two-dimensional zinc(II)-based metal-organic framework [Zn • (BA) • (BBI)] was synthesized from 1,2-benzenediacetic acid and 1,1′-(1,4-butanediyl) bis(imidazole) via a solvothermal reaction. The crystal exhibits good chemical stability in the pH range from 2 to 12, and strong fluorescence with excitation/emission maxima of 270/290 nm. The crystal is shown to by a viable fluorescent probe for the detection of ascorbic acid (AA) and the antibiotics chloramphenicol (CHL) and ceftriaxone (CRO). Fluorescence intensity of crystal dispersion is significantly quenched with increasing concentrations of AA/CHL/CRO. Quenching occurs even in the presence of other substances. The assay is fast (5 s) and has a low detection limit (1.6 ppb for AA, 12 ppb for CHL and 3.9 ppb for CRO). The crystal still has a good quenching effect on AA/CHL/CRO after washing and using for five times. The response of the probe is related to the interplay between the MOF and analytes via energy absorption competition.

Schematic diagram of preparing Zn • (BA) • (BBI) and responding to target analytes. BA: 1,2-phenyldiacetic acid; BBI: 1,1′-(1,4-butanediyl)bis(imidazole); Zn • (BA) • (BBI): Crystal chemical formula.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (Grant No. 51771001, 21471001 and 21575001), independent research and development project of Anhui Province (201904a07020001).

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Authors and Affiliations

  1. AnHui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Institutes of Physical Science and Information Technology Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Anhui University, Hefei, 230601, People’s Republic of China

    Wensheng Liu, Changjie Mao, Jiming Song & Helin Niu

  2. Institute of Health Sciences and School of Life Science, AnHui University, Hefei, Anhui, 230601, People’s Republic of China

    Xiaoyan Qu

  3. Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei, 230009, People’s Republic of China

    Chengfeng Zhu

  4. Xuchang Univ, Inst Surface Micro & Nano Mat, Key Lab Micronano Mat Energy Storage & Convers He, Xuchang, 461000, People’s Republic of China

    Yuanhao Gao

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  1. Wensheng Liu
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Liu, W., Qu, X., Zhu, C. et al. A two-dimensional zinc(II)-based metal-organic framework for fluorometric determination of ascorbic acid, chloramphenicol and ceftriaxone. Microchim Acta 187, 136 (2020). https://doi.org/10.1007/s00604-019-3979-3

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