Correction to: Cell Death and Disease
https://doi.org/10.1038/s41419-019-2106-zpublished online 14 November 2019
Since online publication of this article, the authors noticed that in the legend of Fig. 5, the legend to “panel e” was mistakenly omitted. The full text should read as follows:
Fig. 5 a Representative images of SynI-mAb (1.5 μg/mL)-treated hippocampal neurons incubated either with sodium azide (NaN3; 500 nM), PitStop 2 (30 μM) or α FcγR II/III antibody at the indicated concentrations for 72 h. The control condition indicates cells exposed to SynI-mAb in the presence of the NaN3/PitStop2 solvent. After treatments, cells were fixed, permeabilized and incubated with anti-mouse fluorescent secondary antibodies (green). Double staining for βIII-tubulin (blue) was performed after fixation. Scale bars, 10 μm. b Quantification of the immunoreactivity intensity of internalized SynI-mAb. Graph shows mean ± SEM, single neuron data points independent preparations; **p < 0.01, ***p < 0.001, one-way ANOVA/Dunnett’s tests versus control. c Mean frequency and amplitude of mEPSCs (upper panels) and mIPSCs (lower panels) in hippocampal neurons treated with either SynI-mAb (1.5 μg/mL) or vehicle for 72 h in the presence or absence of 500 nM NaN3. d Mean frequency and amplitude of mEPSCs (upper panels) and mIPSCs (lower panels) in hippocampal neurons treated with either control CSF or patient #1 CSF (1.5 μg/mL) for 72 h in the presence or absence of 500 nM NaN3. Graphs show means ± SEM, single neuron data points from three independent preparations; *p < 0.05, **p < 0.01, two-way ANOVA/Bonferroni’s tests. e Expression of FcγII/III receptors in WT and SynI KO hippocampal neurons. Representative images of primary WT and SynI KO hippocampal neurons at 14.
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Edited by A. Verkhratsky
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Rocchi, A., Sacchetti, S., De Fusco, A. et al. Correction: Autoantibodies to synapsin I sequestrate synapsin I and alter synaptic function. Cell Death Dis 11, 27 (2020). https://doi.org/10.1038/s41419-019-2220-y
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DOI: https://doi.org/10.1038/s41419-019-2220-y