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Rapid and green synthesis of 4H-benzo[b]pyrans using triethanolamine as an efficient homogeneous catalyst under ambient conditions

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Abstract

4H-benzo[b]pyrans were obtained rapidly in high yields using triethanolamine as an efficient, eco-friendly and low-cost basic catalyst. One-pot three-component condensation reaction of a series of aldehydes, malononitrile and 1,3-diketones was performed at room temperature. All the products were obtained in high-to-excellent yields and characterized in detail. Green, rapid and mild process, very short reaction times (1–12 min) and simple workup are some of the advantages of this method.

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Acknowledgements

The authors are thankful to Kashan and Alzahra University for their financial support.

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Authors and Affiliations

  1. Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, P.O. Box 8731753153, Kashan, Islamic Republic of Iran

    Reyhaneh Rahnamafa & Leila Moradi

  2. Department of Pharmaceutical Biomaterials, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran

    Mehdi Khoobi

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  1. Reyhaneh Rahnamafa
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  2. Leila Moradi
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Correspondence to Leila Moradi.

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Rahnamafa, R., Moradi, L. & Khoobi, M. Rapid and green synthesis of 4H-benzo[b]pyrans using triethanolamine as an efficient homogeneous catalyst under ambient conditions. Res Chem Intermed 46, 2109–2116 (2020). https://doi.org/10.1007/s11164-020-04081-3

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