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Effect of high-fluoride dentifrice and bracket bonding composite material on enamel demineralization in situ

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Abstract

Objective

This in situ study evaluated the effect of high-fluoride dentifrice (5000 μg F/g) and fluoride-containing bonding composite resin on enamel demineralization adjacent to orthodontic brackets.

Methods

Ten volunteers wore palatal appliances containing bovine enamel blocks with metallic brackets bonded with fluoride-free or fluoride-containing composite resin. During three phases of 14 days each, three dentifrices with different fluoride concentrations (0, 1100, and 5000 μg F/g) were tested. The cariogenic challenge consisted of 20% sucrose solution dripped 8x/day onto the dental blocks. At the end of each phase, biofilm formed was collected for fluoride analysis. Cross section hardness was performed in enamel blocks, and the lesion area was calculated. Data were analyzed by two-way ANOVA followed by Tukey post hoc test (α = 5%).

Results

The only signicant factor for all the variables under study was the dentifrice. Smaller lesion area and higher fluoride concentration on biofilm were found in 5000 μg F/g group, irrespective of bonding composite resin (p < 0.001). Neither bracket-bonding composite resin nor the interaction between the factors was statistically significant (p > 0.05) for all the variables.

Conclusion

High-fluoride dentifrice is effective in reducing demineralization on enamel adjacent to orthodontic brackets, while the fluoride-containing bonding composite resin does not influence it.

Clinical Significance

Since high-fluoride dentifrice was able to reduce demineralization adjacent to brackets, it can be an option to caries management in orthodontics patients.

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References

  1. Hadler-Olsen S, Sandvik K, El-Agroudi MA, Øgaard B (2012) The incidence of caries and white spot lesions in orthodontically treated adolescents with a comprehensive caries prophylactic regimen--a prospective study. Eur J Orthod 34:633–639. https://doi.org/10.1093/ejo/cjr068

    Article  PubMed  Google Scholar 

  2. Sundararaj D, Venkatachalapathy S, Tandon A, Pereira A (2015) Critical evaluation of incidence and prevalence of white spot lesions during fixed orthodontic appliance treatment: a meta-analysis. J Int Soc Prev Community Dent 5:433–439. https://doi.org/10.4103/2231-0762.167719

    Article  PubMed  PubMed Central  Google Scholar 

  3. Mei L, Chieng J, Wong C, Benic G, Farella M (2017) Factors affecting dental biofilm in patients wearing fixed orthodontic appliances. Prog Orthod 18:4. https://doi.org/10.1186/s40510-016-0158-5

    Article  PubMed  PubMed Central  Google Scholar 

  4. Derks A, Katsaros C, Frencken JE, van't Hof M, Kuijpers-Jagtman AM (2004) Caries-inhibiting effect of preventive measures during orthodontic treatment with fixed appliances. A systematic review. Caries Res 38:413–420. https://doi.org/10.1159/000079621

    Article  PubMed  Google Scholar 

  5. de Moura MS, de Melo Simplício AH, Cury JA (2006) In-vivo effects of fluoridated antiplaque dentifrice and bonding material on enamel demineralization adjacent to orthodontic appliances. Am J Orthod Dentofac Orthop 130:357–363. https://doi.org/10.1016/j.ajodo.2004.12.026

    Article  Google Scholar 

  6. Alexander SA, Ripa LW (2000) Effects of self-applied topical fluoride preparations in orthodontic patients. Angle Orthod 70:424–430. https://doi.org/10.1043/0003-3219 (2000)070<0424:EOSATF>2.0.CO;2

    Article  PubMed  Google Scholar 

  7. Amaechi BT, Ramalingam K, Mensinkai PK, Chedjieu I (2012) In situ remineralization of early caries by a new high-fluoride dentifrice. Gen Dent 60:e186–e192

    PubMed  Google Scholar 

  8. Benson PE, Parkin N, Millett DT et al (2004) Fluorides for the prevention of white spots on teeth during fixed brace treatment. In: Benson PE (ed) Cochrane database of systematic reviews. John Wiley & Sons, Ltd, Chichester, p CD003809

    Google Scholar 

  9. Nascimento PL, Fernandes MT, Figueiredo FE, Faria-E-Silva AL (2016) Fluoride-releasing materials to prevent white spot lesions around orthodontic brackets: a systematic review. Braz Dent J 27:101–107. https://doi.org/10.1590/0103-6440201600482

    Article  PubMed  Google Scholar 

  10. Kirschneck C, Christl J-J, Reicheneder C, Proff P (2016) Efficacy of fluoride varnish for preventing white spot lesions and gingivitis during orthodontic treatment with fixed appliances-a prospective randomized controlled trial. Clin Oral Investig 20(9):2371–2378. https://doi.org/10.1007/s00784-016-1730-6

    Article  PubMed  Google Scholar 

  11. Stecksén-Blicks C, Renfors G, Oscarson ND, Bergstrand F, Twetman S (2007) Caries-preventive effectiveness of a fluoride varnish: a randomized controlled trial in adolescents with fixed orthodontic appliances. Caries Res 41(6):455–459. https://doi.org/10.1159/000107932

    Article  PubMed  Google Scholar 

  12. Benson PE, Parkin N, Dyer F, et al (2013) Fluorides for the prevention of early tooth decay (demineralised white lesions) during fixed brace treatment. Cochrane Database Syst Rev CD003809. https://doi.org/10.1002/14651858.CD003809.pub3

  13. Derks A, Kuijpers-Jagtman AM, Frencken JE, van't Hof M, Katsaros C (2007) Caries preventive measures used in orthodontic practices: an evidence-based decision? Am J Orthod Dentofac Orthop 132:165–170. https://doi.org/10.1016/j.ajodo.2005.10.028

    Article  Google Scholar 

  14. Sonesson M, Twetman S, Bondemark L (2014) Effectiveness of high-fluoride toothpaste on enamel demineralization during orthodontic treatment-a multicenter randomized controlled trial. Eur J Orthod 36:678–682. https://doi.org/10.1093/ejo/cjt096

    Article  PubMed  Google Scholar 

  15. Noronha MDS, Romão DA, Cury JA, Tabchoury CPM (2016) Effect of fluoride concentration on reduction of enamel demineralization according to the cariogenic challenge. Braz Dent J 27:393–398. https://doi.org/10.1590/0103-6440201600831

    Article  Google Scholar 

  16. Al-Mulla A, Karlsson L, Kharsa S et al (2010) Combination of high-fluoride toothpaste and no post-brushing water rinsing on enamel demineralization using an in-situ caries model with orthodontic bands. Acta Odontol Scand 68:323–328. https://doi.org/10.3109/00016357.2010.512863

    Article  PubMed  Google Scholar 

  17. Vale GC, Cruz PF, Bohn ACCE (2015) De Moura MS (2015) salivary fluoride levels after use of high-fluoride dentifrice. Sci World J 2015:30217. https://doi.org/10.1155/2015/302717

    Article  Google Scholar 

  18. Tenuta LM, Cury JA (2013) Laboratory and human studies to estimate anticaries efficacy of fluoride toothpastes. Monogr Oral Sci 23:108–124. https://doi.org/10.1159/000350479 Review

    Article  PubMed  Google Scholar 

  19. Marinho VC, Higgins JP, Sheiham A, Logan S (2003) Fluoride toothpastes for preventing dental caries in children and adolescents. Cochrane Database Syst Rev. (1):CD002278. Review

  20. Fernández CE, Tenuta LMA, Del Bel Cury AA et al (2017) Effect of 5,000 ppm fluoride dentifrice or 1,100 ppm fluoride dentifrice combined with acidulated phosphate fluoride on caries lesion inhibition and repair. Caries Res 51:179–187. https://doi.org/10.1159/000453624

    Article  PubMed  Google Scholar 

  21. Ccahuana-Vásquez RA, Tabchoury CPM, Tenuta LMA et al (2006) Effect of frequency of sucrose exposure on dental biofilm composition and enamel demineralization in the presence of fluoride. Caries Res 41(1):9–15. https://doi.org/10.1159/000096100

    Article  Google Scholar 

  22. Featherstone JD, Mellberg JR (1981) Relative rates of progress of artificial carious lesions in bovine, ovine and human enamel. Caries Res 15(1):109–114

    Article  Google Scholar 

  23. Dominici JT, Eleazer PD, Clark SJ, Staat RH, Scheetz JP (2001) Disinfection/sterilization of extracted teeth for dental student use. J Dent Educ 65:1278–1280

    Article  Google Scholar 

  24. Hara AT, Queiroz CS, Paes Leme AF, Serra MC, Cury JA (2003) Caries progression and inhibition in human and bovine root dentine in situ. Caries Res 37:339–344. https://doi.org/10.1159/000072165

    Article  PubMed  Google Scholar 

  25. Fernández CE, Tenuta LMA, Cury JA (2015) Período de wash-out en diseños experimentales cruzados con dentífrico de alta concentración de fluoruro. Rev Clínica Periodoncia, Implantol y Rehabil Oral 8:1–6. https://doi.org/10.1016/j.piro.2014.12.002

    Article  Google Scholar 

  26. Lima CV, Cury JA, Vale GC, et al (2015) Total fluoride intake by children from a tropical Brazilian City. Caries Res. 49. https://doi.org/10.1159/000442029

  27. Cury JA, Rebelo MAB, Del Bel Cury AA et al (2000) Biochemical composition and Cariogenicity of dental plaque formed in the presence of sucrose or glucose and fructose. Caries Res 34:491–497. https://doi.org/10.1159/000016629

    Article  PubMed  Google Scholar 

  28. Cury JA, do Amaral RC, LMA T et al (2010) Low-fluoride toothpaste and deciduous enamel demineralization under biofilm accumulation and sucrose exposure. Eur J Oral Sci 118:370–375. https://doi.org/10.1111/j.1600-0722.2010.00745.x

    Article  PubMed  Google Scholar 

  29. Featherstone JD, ten Cate JM, Shariati M, Arends J (1983) Comparison of artificial caries-like lesions by quantitative microradiography and microhardness profiles. Caries Res 17(5):385–391

    Article  Google Scholar 

  30. Kielbassa AM, Wrbas KT, Schulte-Mönting J, Hellwig E (1999 Mar) Correlation of transversal microradiography and microhardness on in situ-induced demineralization in irradiated and nonirradiated human dental enamel. Arch Oral Biol 44(3):243–251

    Article  Google Scholar 

  31. Nordström A, Mystikos C, Ramberg P, Birkhed D (2009) Effect on de novo plaque formation of rinsing with toothpaste slurries and water solutions with a high fluoride concentration (5,000 ppm). Eur J Oral Sci 117:563–567. https://doi.org/10.1111/j.1600-0722.2009.00674.x

    Article  PubMed  Google Scholar 

  32. Nordström A, Birkhed D (2010) Preventive effect of high-fluoride dentifrice (5,000 ppm) in caries-active adolescents: a 2-year clinical trial. Caries Res 44:323–331. https://doi.org/10.1159/000317490

    Article  PubMed  Google Scholar 

  33. Nordström A, Birkhed D (2013) Effect of a third application of toothpastes (1450 and 5000 ppm F), including a “massage” method on fluoride retention and pH drop in plaque. Acta Odontol Scand 71:50–56. https://doi.org/10.3109/00016357.2011.654238

    Article  PubMed  Google Scholar 

  34. Mannaa A, Carlén A, Zaura E, Buijs MJ, Bukhary S, Lingström P (2014) Effects of high-fluoride dentifrice (5,000-ppm) on caries-related plaque and salivary variables. Clin Oral Investig 18:1419–1426. https://doi.org/10.1007/s00784-013-1119-8

    Article  PubMed  Google Scholar 

  35. Pessan JP, Conceição JM, Grizzo LT, Székely M, Fazakas Z, Buzalaf MA (2015) Intraoral fluoride levels after use of conventional and high-fluoride dentifrices. Clin Oral Investig 19:955–958. https://doi.org/10.1007/s00784-015-1426-3

    Article  PubMed  Google Scholar 

  36. Melo MAS, Morais WA, Passos VF, Lima JPM, Rodrigues LKA (2014 May) Fluoride releasing and enamel demineralization around orthodontic brackets by fluoride-releasing composite containing nanoparticles. Clin Oral Investig 18(4):1343–1350. https://doi.org/10.1007/s00784-013-1073-5

    Article  PubMed  Google Scholar 

  37. Burke FM, Ray NJ, McConnell RJ (2006) Fluoride-containing restorative materials. Int Dent J 56:33–43

    Article  Google Scholar 

  38. Gorelick L, Geiger AM, Gwinnett AJ (1982) Incidence of white spot formation after bonding and banding. Am J Orthod 81:93–98

    Article  Google Scholar 

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Acknowledgments

The authors express their appreciation to the volunteers for their valuable participation.

Funding

This study had financial support from Coordination of Improvement of Higher-Level Personnel (CAPES) – Procad Program (Process n. 88881.068416/2014-01).

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Correspondence to Glauber Campos Vale.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Ferreira, R.S., Ricomini-Filho, A.P., Tabchoury, C.P. et al. Effect of high-fluoride dentifrice and bracket bonding composite material on enamel demineralization in situ. Clin Oral Invest 24, 3105–3112 (2020). https://doi.org/10.1007/s00784-019-03182-7

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