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Adrenal cortical carcinoma: pathology, genomics, prognosis, imaging features, and mimics with impact on management

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Abstract

Adrenocortical carcinoma (ACC) is a rare tumor with a poor prognosis. Most tumors are either metastatic or locally invasive at the time of diagnosis. Differentiation between ACC and other adrenal masses depends on clinical, biochemical, and imaging factors. This review will discuss the genetics, pathological, and imaging feature of ACC.

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  1. Ayahallah A. Ahmed and Aaron J. Thomas contributed equally to this work.

Authors and Affiliations

  1. Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX, 77030, USA

    Ayahallah A. Ahmed, Dhakshina Moorthy Ganeshan, Katherine J. Blair, Ali I. Morshid & Khaled M. Elsayes

  2. Department of Radiology, Baylor College of Medicine, Houston, TX, USA

    Aaron J. Thomas

  3. Department of Radiology, University of Florida College of Medicine, Jacksonville, FL, USA

    Chandana Lall

  4. Department of Radiology, University of Kentucky, Lexington, Kentucky, USA

    James T. Lee

  5. Departments of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA

    Mouhammed A. Habra

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  1. Ayahallah A. Ahmed
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Ahmed, A.A., Thomas, A.J., Ganeshan, D.M. et al. Adrenal cortical carcinoma: pathology, genomics, prognosis, imaging features, and mimics with impact on management. Abdom Radiol 45, 945–963 (2020). https://doi.org/10.1007/s00261-019-02371-y

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