Letter to the EditorScreening for hyperglycerolemia by triglyceride assay in urine
Section snippets
Case presentation
A 34-year-old man with no toxic habits was referred to the lipid clinic for mild/moderate hypertriglyceridemia known since childhood. He maintains a healthy lifestyle and had received various lipid-lowering drugs (pitavastatin, fenofibrate, gemfibrozil, and omega-3 fatty acids), which failed to reduce his plasma triglycerides. His father has type 2 diabetes with mixed dyslipidemia responding to statin therapy; his mother is hypertensive with a normal lipid profile, and his 41-year-old sister
Discussion
One of the prominent clinical signs suggesting pseudohypertriglyceridemia is the lack of turbidity on visual inspection of the serum sample. Ordinarily, a true serum triglyceride level ≥ 300 mg/dL will lead to turbidity, obscuring newsprint held behind the specimen tube. When glycerolemia masquerading as hypertriglyceridemia is suspected, lipid testing using a blank for free glycerol is recommended.6 Furthermore, marked glyceroluria is observed on urine organic acid chromatography. Because not
Acknowledgments
Authors' contributions: All authors materially participated in the preparation of this article and have approved the final version.
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