Skip to main content
SpringerLink
Log in

A new EPR dosimeter based on glutamic acid for radiation processing application

  • Original Article
  • Published:
Radiation and Environmental Biophysics Aims and scope Submit manuscript

Abstract

l-Glutamic acid (L-GA) pellets (3.8 mm × 4 mm) and powder dosimeters were studied in the dose range of 0.1–150 kGy using the electron paramagnetic resonance (EPR) technique. The EPR spectra of irradiated L-GA pellets showed an EPR signal with eight lines, and the intensity of the signal increased with an increase of absorbed dose. The results obtained in terms of the energy-absorption coefficients suggest a similar performance of the L-GA pellets as compared to alanine pellets. The value of the temperature coefficient for the L-GA pellets during irradiation was around − 0.08%/°C which is lower than that reported for alanine dosimeter, 0.14%/°C. The influence of humidity on the pellet response was found to be negligible; i.e., the increase in response was only about 2% for a relative humidity of up to 94%. The response of L-GA powder reached stability 4 h after irradiation and continued to be stable until 47 days after irradiation. In contrast, the response of the L-GA pellet dosimeter reached stability 22 h after irradiation and continued to be stable until 8 days after irradiation. For routine applications, the L-GA pellet dosimeter should be analyzed during the stable period after irradiation, to minimize the uncertainties in dose assessment. The overall two-sigma uncertainties in absorbed dose estimation were 5.1% and 3.9% for the dose ranges of 0.1–15 kGy and 15–150 kGy, respectively. It is concluded that L-GA pellets represent a promising dosimeter material for quantification of radiation doses in food irradiation, medical sterilization and polymer modification.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12

[data taken from Hubbell and Seltzer (2004)]

Similar content being viewed by others

References

  • Abdel-fattah AA, Ezz El-Din H, Abdel-rehim F (2004) New alanine/EPR dosimeter using EVA copolymer/paraffin as A binder for high-dose radiation dosimetry: performance characterization. Int J Polym Mater Polym Biomater 53:927–939

    Article  Google Scholar 

  • Abdel-Fattah AA, Abdel-Rehim F, Soliman YS (2012) A new label dosimetry system based on pentacosa-diynoic acid monomer for low dose applications. Radiat Phys Chem 81:70–76

    Article  ADS  Google Scholar 

  • Alkhorayef M, Mansour A, Sulieman A et al (2017) Evaluation of dose uncertainty in radiation processing using EPR spectroscopy and butylated hydroxytoluene rods as dosimetry system. Radiat Phys Chem 141:50–56

    Article  ADS  Google Scholar 

  • Bakan MH, Aydin M, Osmanolu E (2010) Investigation of 60Co γ-irradiated l-(−) malic acid, N-methyl-dl-valine and l-glutamic acid γ-ethyl ester by electron paramagnetic resonance technique. J Mol Struct 983:200–202

    Article  ADS  Google Scholar 

  • Beshir WB, Abdel-Fattah AA, Abdel-Rehim F, Hassan HM (2012) EPR dosimetric properties of radiation—formed radicals in arginine monohydrochloride. J Photochem Photobiol B Biol 116:1–6

    Article  Google Scholar 

  • Bracco P, Costa L, Luda MP, Billingham N (2018) A review of experimental studies of the role of free-radicals in polyethylene oxidation. Polym Degrad Stab 155:67–83

    Article  Google Scholar 

  • Chen F, Graeff CFO, Baffa O (2007) Response of l-alanine and 2-methylalanine minidosimeters for K-band (24 GHz) EPR dosimetry. Nucl Instrum Methods Phys Res Sect B Beam Interact Mater At 264:277–281

    Article  ADS  Google Scholar 

  • Ciesielski B, Wielopolski L (1994) The effects of dose and radiation quality on the shape and power saturation of the EPR signal in alanine. Radiat Res 140:105–111

    Article  ADS  Google Scholar 

  • Desrosiers MF, Peters M, Puhl JM (2009) A study of the alanine dosimeter irradiation temperature coefficient from 25 to 80 °C. Radiat Phys Chem 78:465–467. https://doi.org/10.1016/j.radphyschem.2009.03.026

    Article  ADS  Google Scholar 

  • Eid S, Ebraheem S, Sobhy A (2014) ESR dosimetric properties of sodium glutamate. Egypt J Rad Sci Appl 27:151–164

    Article  Google Scholar 

  • Gallo S, Iacoviello G, Panzeca S, Veronese I, Bartolotta A, Dondi D, Gueli AM, Loi G, Longo A, Mones E, Marrale M (2017) Characterization of phenolic pellets for ESR dosimetry in photon beam radiotherapy. Radiat Environ Biophys 56:471–480

    Article  Google Scholar 

  • Gancheva V, Sagstuen E, Yordanov ND (2006) Study on the EPR/dosimetric properties of some substituted alanines. Radiat Phys Chem 75:329–335

    Article  ADS  Google Scholar 

  • Greenspan L (1977) Humidity fixed points of binary saturated aqueous solutions. J Res Natl Bur Stand Sect A Phys Chem 81:89–96

    Article  Google Scholar 

  • Guidelli EJ, Lima IS, Baffa O (2018) Monosodium glutamate for accidental, retrospective, and medical dosimetry using electron spin resonance. Radiat Environ Biophys 57:349–356

    Article  Google Scholar 

  • Hansen JW, Olsen KJ (1989) Predicting decay in free-radical concentration in l-α-alanine following high-LET radiation exposures. Int J Radiat Appl Instrum Part A Appl Radiat Isot 40:10–12

    Article  Google Scholar 

  • Hassan GM, Ikeya M (2000) Metal ion-organic compound for high sensitive ESR dosimetry. Appl Radiat Isot 52:1247–1254

    Article  Google Scholar 

  • Hubbell JH, Seltzer SM (2004) Tables of X-ray mass attenuation coefficients and mass energy-absorption coefficients (version 1.4). http://physics.nist.gov/xaamdi. Accessed 2019

  • ISO/ASTM 51707 (2015) Guide for estimating uncertainties in dosimetry for radiation processing. In: Annual book of ASTM standards. ASTM International, West Conshohocken, PA

  • ISO/ASTM51607 (2013) Practice for use of the alanine-EPR dosimetry system. In: Annual book of ASTM standards. ASTM International, West Conshohocken, PA

  • Khoury HJ, da Silva EJ, Mehta K, de Barros VS, Asfora VK, Guzzo PL, Parker AG (2015) Alanine-EPR as a transfer standard dosimetry system for low energy X radiation. Radiat Phys Chem 116:147–150

    Article  ADS  Google Scholar 

  • Kornacka EM, Przybytniak G, Świeszkowski W (2013) The influence of crystallinity on radiation stability of UHMWPE. Radiat Phys Chem 84:151–156

    Article  ADS  Google Scholar 

  • Lelie S, Hole EO, Duchateau M, Schroeyers W, Schreurs S, Verellen D (2013) The investigation of lithium formate hydrate, sodium dithionate and N-methyl taurine as clinical EPR dosimeters. Radiat Meas 59:218–224

    Article  Google Scholar 

  • Lin WC, Mcdowell CA, Rowlands JR (1961) Electron spin resonance of X-ray irradiated single crystals of glutamic acid hydrochloride. J Chem Phys 35:757–758

    Article  ADS  Google Scholar 

  • Lund A, Olsson S, Bonora M, Lund E, Gustafsson H (2002) New materials for ESR dosimetry. Spectrochim Acta Part A Mol Biomol Spectrosc 58:1301–1311

    Article  ADS  Google Scholar 

  • Lund E, Gustafsson H, Danilczuk M, Sastry MD, Lund A, Vestad TA, Malinen E, Hole EO, Sagstuen E (2005) Formates and dithionates: sensitive EPR-dosimeter materials for radiation therapy. Appl Radiat Isot 62:317–324

    Article  Google Scholar 

  • Maghraby A, Mansour A, Tarek E (2012) Taurine for EPR dosimetry. Radiat Environ Biophys 51:255–261

    Article  Google Scholar 

  • Nagy V, Puhl JM, Desrosiers MF (2000) Advancements in accuracy of the alanine dosimetry system. Part 2. The influence of the irradiation temperature. Radiat Phys Chem 57:1–9

    Article  ADS  Google Scholar 

  • Nette HP, Onori S, Fattibene P, Regulla D, Wieser A (1993) Coordinated research efforts for establishing an in international radiotherapy dose intercomparison service based on the alanine/ESR system. Appl Radiat Isot 44:7–11

    Article  Google Scholar 

  • Ogawa M, Ishigure K, Oshima K (1980) ESR study of irradiated single crystals of amino acids—I. Glutamic acid and glutamic acid hydrochloride. Radiat Phys Chem 16:281–287

    ADS  Google Scholar 

  • Olsson SK, Lund E, Lund A (2000) Development of ammonium tartrate as an ESR dosimeter material for clinical purposes. Appl Radiat Isot 52:1235–1241

    Article  Google Scholar 

  • Olsson S, Sagstuen E, Bonora M, Lund A (2002) EPR dosimetric properties of 2-methylalanine: EPR, ENDOR and FT-EPR investigations. Radiat Res 157:113–121

    Article  ADS  Google Scholar 

  • Osmanoǧlu Ş, Aydin M, Osmanoǧlu YE, Dicle IY, Başkan MH (2011) Structure and behaviour of the free radicals generated in gamma irradiated amino acid and iminodiacetic acid derivatives. Spectrochim Acta Part A Mol Biomol Spectrosc 78:1611–1614

    Article  ADS  Google Scholar 

  • Piroonpan T, Katemake P, Panritdam E, Pasanphan W (2017) Alternative chitosan-based EPR dosimeter applicable for a relatively wide range of gamma radiation doses. Radiat Phys Chem 141:57–65

    Article  ADS  Google Scholar 

  • Prydz S, Henriksen T (1961) Radiation induced free radicals in alanine and some related amino acids. Electron spin resonance studies. Acta Chem Scand 15:791–802

    Article  Google Scholar 

  • Regulla DF, Deffner U (1982) Dosimetry by ESR spectroscopy of alanine. Int J Appl Radiat Isot 33:1101–1114

    Article  Google Scholar 

  • Rushdi MAH, Abdel-Fattah AA, Sherif MM, Soliman SS, Mansour A (2014) Strontium sulfate as an EPR dosimeter for radiation technology application. Radiat Phys Chem 106:130–135

    Article  ADS  Google Scholar 

  • Rushdi MAH, Abdel-Fattah AA, Soliman YS (2017) Radiation-induced defects in strontium carbonate rod for EPR dosimetry applications. Radiat Phys Chem 131:1–6

    Article  ADS  Google Scholar 

  • Sagstuen E, Hole EO (2009) Radiation produced radicals. In: Brustolon M, Giamello E (eds) Electron paramagnetic resonance, a practitioner’s toolkit. Wiley, Hoboken, pp 325–382

    Chapter  Google Scholar 

  • Sharpe P, Miller A (2009) Guidelines for the calibration of routine dosimetry systems for use in radiation processing. NPL report CIRM 29

  • Sleptchonok OF, Nagy V, Desrosiers MF (2000) Advancements in accuracy of the alanine dosimetry system. Part 1. The effects of environmental humidity. Radiat Phys Chem 57:115–133

    Article  ADS  Google Scholar 

  • Soliman YS, Abdel-Fattah AA (2012) Magnesium lactate mixed with EVA polymer/paraffin as an EPR dosimeter for radiation processing application. Radiat Phys Chem 81:1910–1916

    Article  ADS  Google Scholar 

  • Soliman YS, Ali LI, Moustafa H, Tadros SM (2014) EPR dosimetric properties of 2-methylalanine pellet for radiation processing application. Radiat Phys Chem 102:11–15

    Article  ADS  Google Scholar 

  • Wexler A, Hasegawa S (1954) Relative humidity-temperature relationships of some saturated salt solutions in the temperature range 0 °C to 50 °C. J Res Natl Bur Stand 53:19–26

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National Center for Radiation Research and Technology, Atomic Energy Authority, Nasr City, P.O. Box 8029, Cairo, Egypt

    W. B. Beshir, Yasser S. Soliman, A. A. Abdel-Fattah & Ramy Amer Fahim

Authors
  1. W. B. Beshir
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yasser S. Soliman
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. A. Abdel-Fattah
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Ramy Amer Fahim
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yasser S. Soliman.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Beshir, W.B., Soliman, Y.S., Abdel-Fattah, A.A. et al. A new EPR dosimeter based on glutamic acid for radiation processing application. Radiat Environ Biophys 58, 501–511 (2019). https://doi.org/10.1007/s00411-019-00808-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00411-019-00808-y

Keywords

Search

Navigation