Editorial overview: Functionalizing cancer genomes in the era of big data

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Roland Rad is Director of the Institute of Molecular Oncology and Functional Genomics at the Technical University of Munich (TUM). He is also Professor for Translational Oncology at the Department of Medicine II at TUM and the German Cancer Research Center (DKFZ). He did his doctoral studies and clinical training at TUM and worked as a postdoctoral fellow with Allan Bradley at the Wellcome Trust Sanger Institute, Cambridge, UK. Focus areas of Rad´s research are gene discovery, analysis of gene function and signaling in cancer. His laboratory develops tools and methods for forward and reverse genetics in cells and model organisms to address questions in basic and translational cancer research.

Michael Boutros is the head of the Division Signaling and Functional Genomics and Speaker of the Functional and Structural Genomics Program at the German Cancer Research Center (DKFZ). He is also Professor for Cell and Molecular Biology at Heidelberg University. After his PhD with Marek Mlodzik at the European Molecular Biology Laboratory (EMBL), he joined the laboratory of Norbert Perrimon at Harvard Medical School as a postdoctoral fellow. Michael Boutros’ research interests include functional genomic approaches to understand the regulation of cellular signaling in normal and cancer cells. His laboratory further develops and applies high-throughput screening methodologies to dissect genetic networks and genotype-specific vulnerabilities.

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