Elsevier

Research in Microbiology

Volume 170, Issue 8, November–December 2019, Pages 392-398
Research in Microbiology

Energy coupling in ABC exporters

https://doi.org/10.1016/j.resmic.2019.08.003Get rights and content
Under an Elsevier user license
open archive

Abstract

Multidrug transporters are important and interesting molecular machines that extrude a wide variety of cytotoxic drugs from target cells. This review summarizes novel insights in the energetics and mechanisms of bacterial ATP-binding cassette multidrug transporters as well as recent advances connecting multidrug transport to ion and lipid translocation processes in other membrane proteins.

Keywords

Bioenergetics
ABC transporter
Multidrug transport
Transport mechanisms

Cited by (0)