Epilogue: The future of Laron syndrome — The need for changes
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Cited by (7)
Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver
2018, Molecular MetabolismCitation Excerpt :As a consequence, LS patients have low levels of insulin-like growth factor 1 (IGF1) and – due to the lack of feedback inhibition of GH secretion – high levels of GH [3]. A few hundred cases of LS have been reported world-wide, caused by a variety of GHR mutations (reviewed in [4]). Among them is an isolated, more homogeneous population of GHR deficient patients in Ecuador with only two distinct mutations of the GHR gene [5–7].
Transient juvenile hypoglycemia in growth hormone receptor deficiency - mechanistic insights from Laron syndrome and tailored animal models
2021, European Journal of EndocrinologyNutrients and pathways that regulate health span and life span
2020, Geriatrics (Switzerland)Growth hormone insensitivity (Laron syndrome): Report of a new family and review of Brazilian patients
2019, Genetics and Molecular BiologyA 42-year-old woman with untreated growth hormone insensitivity, diabetic retinopathy, and gene sequencing identifies a variant of laron syndrome
2019, American Journal of Case Reports
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