- 作 者: ( "changjian lin" OR "chang-jian lin" )
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Chondroitin sulfate microspheres anchored with drug-loaded liposomes play a dual antioxidant role in the treatment of osteoarthritisActa Biomaterialia (IF 10.633) Pub Date : 2022-08-12 ,DOI:10.1016/j.actbio.2022.07.052Yuzhe He, Miao Sun, Jirong Wang, Xiaofu Yang, Changjian Lin, Lujie Ge, Chenting Ying, Kai Xu, An Liu, Lidong WuReactive oxygen species (ROS) play a critical role in the pathogenesis of osteoarthritis. The injection of a single antioxidant drug is characterized by low drug utilization and short residence time in the articular cavity, limiting the therapeutic effect of antioxidant drugs on osteoarthritis. Currently, the drug circulation half-life can be extended using delivery vehicles such as liposomes and microspheres ...
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Nitidine Chloride Alleviates Inflammation and Cellular Senescence in Murine Osteoarthritis Through Scavenging ROSFrontiers in Pharmacology (IF 5.988) Pub Date : 2022-07-22 ,DOI:10.3389/fphar.2022.919940Changjian Lin, Lujie Ge, Luping Tang, Yuzhe He, Safwat Adel Abdo Moqbel, Kai Xu, Diana Ma, Xing Zhou, Jisheng Ran, Lidong Wu
Osteoarthritis (OA) is one of the most common chronic musculoskeletal disorder worldwide, representing a major source of disability, pain and socioeconomic burden. Yet the effective pharmaceutical treatments applied in the clinical works are merely symptomatic management with uncertainty around their long-term safety and efficacy, namely no drugs currently are capable of modulating the biological progression
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HemoglobinA1c Is a Risk Factor for Changes of Bone Mineral Density: A Mendelian Randomization StudyFrontiers in Endocrinology (IF 6.055) Pub Date : 2022-07-18 ,DOI:10.3389/fendo.2022.942878Xiaoxiao Ji, Jianqiao Hong, Zihao Qu, Weinan Yang, Yibo Wang, Jiyan Lin, Congsun Li, Jie Wang, Haochen Mou, Mingmin Shi, Chenhe Zhou, Wei Wang, Changjian Lin, Shigui Yan, Haobo Wu
Background As a valuable blood glucose measurement, HemoglobinA1c (HbA1c) is of great clinical value for diabetes. However, in previous observational studies, studies on its effect on bone mineral density (BMD) have different results. This study aimed to use Mendelian randomization (MR) to assess the effect of HbA1c on bone mineral density and fracture risk, and try to further explore whether this
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Cell osteogenic bioactivity mediated precisely by varying scaled micro-pits on ordered micro/nano hierarchical structures of titaniumRegenerative Biomaterials (IF 5.763) Pub Date : 2022-07-01 ,DOI:10.1093/rb/rbac046Yanmei Zhang, Xiankuan Wang, Yaxian Li, Jianhe Liang, Pinliang Jiang, Qiaoling Huang, Yun Yang, Hongping Duan, Xiang Dong, Gang Rui, Changjian Lin
Hierarchical surface structures with micro-nano scale play a crucial role in regulation of cell proliferation and osteogenic differentiation. It has been proven that cells are extremely sensitive to the nanoscaled structure and show multifarious phenotypes. Though a vital function of microstructure on osseointegration has been confirmed, the cell performances response to different microscaled structure
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Long-term outcomes of a time to isolation – based strategy for cryoballoon ablation compared to radiofrequency ablation in patients with symptomatic paroxysmal atrial fibrillationPacing and Clinical Electrophysiology (IF 1.912) Pub Date : 2022-06-29 ,DOI:10.1111/pace.14556Yue Wei, Lin Chen, Jiang Cao, Shaowen Liu, Tianyou Ling, Xinmiao Huang, Genqing Zhou, Changjian Lin, Yun Xie, Yangyang Bao, Qingzhi Luo, Jiawen Ye, Ning Zhang, Qi Jin, Liqun WuCryoballoon ablation (CBA) is one of the most commonly used technologies designed for pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (PAF), although the dosing of CBA remains controversial. We evaluated the long-term efficacy and safety of a novel individualized strategy of CBA compared to radiofrequency ablation (RFA) for patients with PAF. ...
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Association of Circulating IgE and CML Levels with In-Stent Restenosis in Type 2 Diabetic Patients with Stable Coronary Artery DiseaseJournal of Cardiovascular Development and Disease Pub Date : 2022-05-13 ,DOI:10.3390/jcdd9050157Jingmeng Liu, Qiujing Chen, Lin Lu, Qi Jin, Yangyang Bao, Tianyou Ling, Changjian Lin, Fenghua Ding, Xiaoqun Wang, Weifeng Shen, Ying Shen, Yang Dai, Liqun Wu
Background: We investigated whether serum levels of immunoglobin (Ig) E and Nε-carboxymethyl-lysine (CML) are related to in-stent restenosis (ISR) in patients with stable coronary artery disease and type 2 diabetes mellitus (T2DM). Methods: Serum levels of IgE and CML were measured in 196 ISR patients and 220 non-ISR patients with stable angina and T2DM who received angiographic follow-up 12 months
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A Convolutional Neural Network Particle Filter for UUV Target State EstimationIEEE Transactions on Instrumentation and Measurement (IF 5.332) Pub Date : 2022-04-22 ,DOI:10.1109/tim.2022.3169539Changjian Lin, Yuhu Cheng, Xuesong WangEngineering Research Center of Intelligent Control for Underground Space, Ministry of Education, and the School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, ChinaThe challenges facing unmanned underwater vehicle (UUV) target state estimation are observation uncertainty, the unpredictability of the target motion model, and the complex relative motion of the moving target to the observer. Aiming at the above problems, a convolutional neural network particle filter (CNNPF) is proposed and applied to UUV target state estimation using forward-looking sonar. First ...
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The feasibility of using remote magnetic navigation system as the primary technological training tool for novice cardiac electrophysiology operators in the catheter ablation of left-sided accessory pathway.Cardiology Journal Pub Date : 2022-04-04 ,DOI:10.5603/cj.a2022.0015Guanhua Wu,Qingzhi Luo,Yangyang Bao,Yue Wei,Changjian Lin,Ning Zhang,Tianyou Ling,Kang Chen,Wenqi Pan,Liqun Wu,Yun Xie,Qi JinDepartment of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
BACKGROUND For novice operators, mastering catheter ablation of left-sided accessory pathway (LSAP) in a short duration of time without compromising efficacy and safety remains a challenge. In this study an attempt to shorten the learning curve by using robotics via a remote magnetic navigation (RMN) system was performed. METHODS Novice physician fellows without prior catheter ablation experience initiated
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Comparison of the Mid-Term Outcomes of Robotic Magnetic Navigation-Guided Radiofrequency Ablation versus Cryoballoon Ablation for Persistent Atrial FibrillationJournal of Cardiovascular Development and Disease Pub Date : 2022-03-17 ,DOI:10.3390/jcdd9030088Xiang Li, Yangyang Bao, Kangni Jia, Ning Zhang, Changjian Lin, Yue Wei, Yun Xie, Qingzhi Luo, Tianyou Ling, Kang Chen, Wenqi Pan, Liqun Wu, Qi JinDepartment of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China.
Introduction: Currently, numerous ablation techniques are available for atrial fibrillation (AF), in addition to manual radio frequency ablation. The aim of this prospective, non-randomized concurrent controlled trial was to compare the mid-term efficacy and procedural outcomes of persistent AF (PerAF) using cryoballoon (CB) and robotic magnetic navigation (RMN). Methods: Two hundred PerAF patients
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Photoelectrocatalytic nitrogen fixation with Vo-BiOBr/TiO2 heterostructured photoelectrode as photocatalystInternational Journal of Hydrogen Energy (IF 7.139) Pub Date : 2022-03-02 ,DOI:10.1016/j.ijhydene.2022.02.026Sheng Lin, Yinhuan Chen, Jiangjian Fu, Lan Sun, Qiaorong Jiang, Jian-Feng Li, Jun Cheng, Changjian Lin, Zhong-Qun TianPhotocatalytic or photoelectrocatalytic nitrogen fixation is considered as a very promising way to reduce energy requirements. Here, Vo-BiOBr/TiO2 nanocomposite photoelectrode was constructed by modifying TiO2 nanotube arrays with BiOBr nanosheets with oxygen vacancies (Vo) for photoelectrocatalytic nitrogen fixation. The oxygen vacancy promotes the adsorption and activation of N2 on the catalyst surface ...
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Utilization of steerable sheath improves the efficiency of atrial fibrillation ablation guided by robotic magnetic navigation compared with fixed-curve sheathClinical Cardiology (IF 3.287) Pub Date : 2022-02-23 ,DOI:10.1002/clc.23801Qingzhi Luo, Yun Xie, Yangyang Bao, Yue Wei, Changjian Lin, Ning Zhang, Tianyou Ling, Kang Chen, Wenqi Pan, Liqun Wu, Qi JinDepartment of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
The objective of this study was to assess the impact of steerable sheaths compared with fixed-curve sheaths on the procedural outcomes of atrial fibrillation (AF) ablation guided by robotic magnetic navigation (RMN).
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Biomimetic hierarchical implant surfaces promote early osseointegration in osteoporotic rats by suppressing macrophage activation and osteoclastogenesisJournal of Materials Chemistry B (IF 7.571) Pub Date : 2022-02-18 ,DOI:10.1039/d1tb02871eXiaohan Dai, Yunyang Bai, Boon Chin Heng, Yiping Li, Zhangui Tang, Changjian Lin, Ousheng Liu, Ying He, Xuehui Zhang, Xuliang DengSuccessful implant–bone integration remains a formidable challenge in osteoporotic patients, because of excessive inflammatory reactions and osteoclastogenesis around the peri-implant bone tissue. This study designed biomimetic micro/sub-micro hierarchical surfaces on titanium implants based on natural bone hierarchical structures to mitigate macrophage-mediated inflammatory reactions, osteoclastogenesis ...
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Association between the rs2106261 polymorphism in the zinc finger homeobox 3 gene and risk of atrial fibrillation: Evidence from a PRISMA-compliant meta-analysis.Medicine (IF 1.817) Pub Date : 2021-12-11 ,DOI:10.1097/md.0000000000027749Yue Wei, Lingjie Wang, Changjian Lin, Yun Xie, Yangyang Bao, Qingzhi Luo, Ning ZhangDepartment of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Previous genome-wide studies have identified an association between the rs2106261 single-nucleotide polymorphism (SNP) in the zinc finger homeobox 3 (ZFHX3) gene and an increased risk of atrial fibrillation (AF). However, this association remains controversial, since conflicting results have been reported in previous studies. We aimed to investigate the association between the ZFHX3 rs2106261 polymorphism
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Anti-inflammatory effects of brucea javanica oil via inhibition of NF-κB activation.American journal of translational research Pub Date : 2021-11-15 ,DOI:Daxuan Wang,Xiujuan Yao,Baosong Xie,Yusheng Chen,Changjian LinOBJECTIVE As a traditional herbal medicine extracted from the seeds of Brucea javanica, Brucea javanica oil (BJO) has been clinically used to treat wart, chronic gastroenteritis and a variety of malignant tumors, including gastrointestinal cancer and lung cancer. We have recently reported the anti-tumor role and possible molecular mechanisms of BJO in treatment of lung cancer. However, it remains elusive ...
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AUV Obstacle Avoidance Planning Based on Deep Reinforcement LearningJournal of Marine Science and Engineering (IF 2.744) Pub Date : 2021-10-23 ,DOI:10.3390/jmse9111166Jianya Yuan, Hongjian Wang, Honghan Zhang, Changjian Lin, Dan Yu, Chengfeng Li
In a complex underwater environment, finding a viable, collision-free path for an autonomous underwater vehicle (AUV) is a challenging task. The purpose of this paper is to establish a safe, real-time, and robust method of collision avoidance that improves the autonomy of AUVs. We propose a method based on active sonar, which utilizes a deep reinforcement learning algorithm to learn the processed sonar
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circFAM160A2 Promotes Mitochondrial Stabilization and Apoptosis Reduction in Osteoarthritis Chondrocytes by Targeting miR-505-3p and SIRT3Oxidative Medicine and Cellular Longevity (IF 7.31) Pub Date : 2021-10-04 ,DOI:10.1155/2021/5712280Jiapeng Bao, Changjian Lin, Xing Zhou, Diana Ma, Lujie Ge, Kai Xu, Safwat Adel Abdo Moqbel, Yuzhe He, Chiyuan Ma, Jisheng Ran, Lidong Wu
Competitive endogenous RNAs (ceRNAs), as a newly identified regulating mechanism, have been demonstrated to play a crucial role in various human diseases. An increasing number of recent studies have revealed that circular RNAs (circRNAs) can function as ceRNAs. However, little is known about the role of circFAM160A2 in the pathological process of osteoarthritis (OA). This study is the first to examine
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Surface Properties of Octacalcium Phosphate Nanocrystals Are Crucial for Their BioactivitiesACS Omega (IF 4.132) Pub Date : 2021-09-20 ,DOI:10.1021/acsomega.1c03278Lili Fan, Yanmei Zhang, Jiejie Hu, Yuan Fang, Ren Hu, Wei Shi, Bin Ren, Changjian Lin, Zhong-Qun Tian
The fundamental structure–biofunction relationship of calcium phosphates (CaPs) remains unclear despite their clinical successes as important biomaterials. Herein, a series of CaP coatings with gradual change of topography and crystallinity is constructed by electrochemical deposition, and the roles of the two basic physicochemical properties are scrutinized for further understanding the mechanism
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Layered double hydroxide (LDH) for multi-functionalized corrosion protection of metals: A reviewJournal of Materials Science & Technology (IF 10.319) Pub Date : 2021-08-27 ,DOI:10.1016/j.jmst.2021.05.078Yanhui Cao, Dajiang Zheng, Fan Zhang, Jinshan Pan, Changjian LinLayered double hydroxide (LDH) has been widely developed in the field of corrosion and protection in recent years based on its unique characteristics including anion capacity, anion exchange ability, structure memory effect, and barrier resistance. This paper comprehensively reviews recent work on the preparations, properties of LDH in the forms of powder and film and their applications in different ...
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Popularity Prediction of Online Contents via Cascade Graph and Temporal InformationAxioms Pub Date : 2021-07-23 ,DOI:10.3390/axioms10030159Yingdan Shang, Bin Zhou, Ye Wang, Aiping Li, Kai Chen, Yichen Song, Changjian Lin
Predicting the popularity of online content is an important task for content recommendation, social influence prediction and so on. Recent deep learning models generally utilize graph neural networks to model the complex relationship between information cascade graph and future popularity, and have shown better prediction results compared with traditional methods. However, existing models adopt simple
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Highly Stretchable, Adhesive, and Self-Healing Silk Fibroin-Dopted Hydrogels for Wearable SensorsAdvanced Healthcare Materials (IF 11.092) Pub Date : 2021-07-21 ,DOI:10.1002/adhm.202101062Li Zhao, Jizhong Zhao, Fan Zhang, Zijie Xu, Fan Chen, Yating Shi, Chen Hou, Yicheng Huang, Changjian Lin, Rui Yu, Wenxi GuoE-mail:yurui@xmu.edu.cn;wxguo@xmu.edu.cn
Adv. Healthcare Mater. 2021, 10, 2002083 DOI: 10.1002/adhm.202002083 In the published version of this article, the word “doped” in misspelled as “dopted” throughout the article. This mistake appears in the Title, the Abstract, the Introduction, and Conclusion. The correct title is: Highly Stretchable, Adhesive, and Self-Healing Silk Fibroin-Doped Hydrogels for Wearable Sensors The correct sentence
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Spironolactone Ameliorates Senescence and Calcification by Modulating Autophagy in Rat Tendon-Derived Stem Cells via the NF-κB/MAPK PathwayOxidative Medicine and Cellular Longevity (IF 7.31) Pub Date : 2021-06-30 ,DOI:10.1155/2021/5519587Kai Xu, Changjian Lin, Diana Ma, Mengyao Chen, Xing Zhou, Yuzhe He, Safwat Adel Abdo Moqbel, Chiyuan Ma, Lidong Wu
Tendinopathy is a disabling musculoskeletal disease, the pathological process of which is tightly associated with inflammation. Spironolactone (SP) has been widely used as a diuretic in clinical practice. Recently, SP has shown anti-inflammatory features in several diseases. Tendon-derived stem cells (TDSCs), a subset cell type from tendon tissue possessing clonogenic capacity, play a vital role in
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Effect of physical barrier and anion-exchange process of nitrate-intercalated ZnAl layered double hydroxide films grown on Al on corrosion protectionSurface & Coatings Technology (IF 4.865) Pub Date : 2021-06-23 ,DOI:10.1016/j.surfcoat.2021.127436Yanhui Cao, Dajiang Zheng, Changjian LinZnAl layered double hydroxide (ZnAl-LDH) film loaded with nitrates was prepared on the surface of pure Al plate by hydrothermal reaction. The anion-exchange process of ZnAl-LDH in corrosive NaCl solution was demonstrated by the X-ray Diffraction (XRD). The corrosion protection behavior of this fabricated film was monitored by performing electrochemical impedance spectroscopy (EIS) up to 39 d. It was ...
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Effect of physical barrier and anion-exchange process of nitrate-intercalated ZnAl layered double hydroxide films grown on Al on corrosion protectionSurface and Coatings Technology Pub Date : 2021-06-23 ,DOI:10.1016/j.surfcoat.2021.127436Yanhui Cao, Dajiang Zheng, Changjian LinZnAl layered double hydroxide (ZnAl-LDH) film loaded with nitrates was prepared on the surface of pure Al plate by hydrothermal reaction. The anion-exchange process of ZnAl-LDH in corrosive NaCl solution was demonstrated by the X-ray Diffraction (XRD). The corrosion protection behavior of this fabricated film was monitored by performing electrochemical impedance spectroscopy (EIS) up to 39 d. It was ...
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Deciphering controversial results of cell proliferation on TiO2 nanotubes using machine learningRegenerative Biomaterials (IF 5.763) Pub Date : 2021-06-21 ,DOI:10.1093/rb/rbab025Ziao Shen, Si Wang, Zhenyu Shen, Yufei Tang, Junbin Xu, Changjian Lin, Xun Chen, Qiaoling Huang
With the rapid development of biomedical sciences, contradictory results on the relationships between biological responses and material properties emerge continuously, adding to the challenge of interpreting the incomprehensible interfacial process. In the present paper, we use cell proliferation on titanium dioxide nanotubes (TNTs) as a case study and apply machine learning methodologies to decipher
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Study on effect of chloride ions on corrosion behavior of reinforcing steel in simulated polluted concrete pore solutions by scanning micro-reference electrode techniqueJournal of Electroanalytical Chemistry (IF 4.598) Pub Date : 2021-06-10 ,DOI:10.1016/j.jelechem.2021.115454Xiao-Ping Wang, Minhua Shao, Chen-Qing Ye, Shi-Gang Dong, Rong-Gui Du, Chang-Jian LinChloride ion (Cl-) attack is a main reason for localized corrosion of reinforcing steel in concrete. Study on the effect of Cl- on corrosion behavior of the steel is of importance for corrosion protection. In this study, reinforcing steel (Q235 carbon steel) passivity in simulated polluted concrete pore solutions at pH 11.50 with different Cl- concentrations was studied by a scanning micro-reference ...
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Wearable hydration and pH sensor based on protein film for healthcare monitoringChemical Papers (IF 2.146) Pub Date : 2021-05-30 ,DOI:10.1007/s11696-021-01627-6Chen Hou,Fan Zhang,Caifeng Chen,Yifan Zhang,Ronghui Wu,Liyun Ma,Changjian Lin,Wenxi Guo,Xiang Yang LiuHydration and pH monitoring provide clinically relevant information of preventative medicine, disease diagnostics, and patient care is of great importance. However, traditional materials have limited in flexible sensors due to the long-term on-skin health monitoring, which requires high flexibility, biocompatibility, biodegradability, comfortableness, and air permeability. In this paper, micro hydration ...
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Construction of ecofriendly anticorrosive composite film ZnAl-LDH by modification of lignin on AA 7075 surfaceMaterials and Corrosion (IF 1.832) Pub Date : 2021-05-13 ,DOI:10.1002/maco.202112402Yanhui Cao, Dajiang Zheng, Changjian LinIn this study, an environment-friendly composite ZnAl-LDH film modified by the rich biomass lignin was prepared on AA 7075 surface successfully. A wide range of characterizations was carried out to obtain the morphology, composition, and structure of this composite film, including scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy (FTIR), and so on. In addition ...
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Differences in D-dimer blood concentration in atrial fibrillation patients with left atrial thrombus or severe left atrial spontaneous echo contrastJournal of Interventional Cardiac Electrophysiology (IF 1.759) Pub Date : 2021-05-03 ,DOI:10.1007/s10840-021-00991-3Changjian Lin, Yangyang Bao, Wei Hua, Ning Zhang, Qi Jin, Yun Xie, Yue Wei, Qingzhi Luo, Zhuhui Liu, Tianyou Ling, Wenqi Pan, Yucai Xie, Liqun WuPurpose Severe left atrial spontaneous echo contrast (SLASEC) is considered the prior stage to thrombosis and a high-risk factor for thrombotic events. Studies have suggested an effect of D-dimer blood concentration on exclusion of left atrial thrombus (LAT), but it remains unclear whether D-dimer concentrations differ between atrial fibrillation (AF) patients with SLASEC or LAT. Methods Nonvalvular ...
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Machine-learning micropattern manufacturingNano Today (IF 18.962) Pub Date : 2021-04-16 ,DOI:10.1016/j.nantod.2021.101152Si Wang, Ziao Shen, Zhenyu Shen, Yuanjun Dong, Yanran Li, Yuxin Cao, Yanmei Zhang, Shengshi Guo, Jianwei Shuai, Yun Yang, Changjian Lin, Xun Chen, Xingcai Zhang, Qiaoling HuangMicropatterning has been widely applied in electronics, biomaterials engineering, and microfluidics studies. A key challenge in using bipolar electrochemistry for fabricating titanium dioxide (TiO2) nanotube micropatterns (TNMs) with desired properties is to balance interrelated experimental parameters and define experimental boundary conditions. For example, it is challenging to determine the anodization ...
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Automatic Feature Selection and Ensemble Classifier for Intrusion DetectionJournal of Physics: Conference Series Pub Date : 2021-04-08 ,DOI:10.1088/1742-6596/1856/1/012067Changjian Lin, Aiping Li, Rong JiangNational University of Defense Technology, Changsha, Hunan, 410000, China
Anomaly-based Intrusion Detection System (ADS) is one of the technologies widely used in network topology. Although many supervised and unsupervised learning methods in the field of machine learning have been used to improve the efficiency of ADS, achieving good performance is still a challenging problem for existing intrusion detection algorithms. Firstly, there are few public datasets available for
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