- 作 者: "yan wang"
-
Correspondence on ‘A pilot study of tofacitinib for refractory Behçet’s syndrome’Annals of the Rheumatic Diseases (IF 27.973) Pub Date : 2023-04-01 ,DOI:10.1136/annrheumdis-2020-219810Jun Zou, Chen-Hong Lin, Yan Wang, Yan Shen, Jian-Long Guan
We carefully read the recent study by Liu et al on the effectiveness of tofacitinib for refractory Behçet’s syndrome (BS).1 In total, 13 patients with BS were enrolled, including 5 cases with vascular involvement, 7 with gastrointestinal (GI) ulcers and one suffering polyarthritis. As an add-on approach, tofacitinib improved the outcomes in all patients with vascular lesions, but unchanged or worsened
...
-
Predicting miRNA-disease associations based on PPMI and attention networkBMC Bioinformatics (IF 3.307) Pub Date : 2023-03-23 ,DOI:10.1186/s12859-023-05152-zXuping Xie, Yan Wang, Kai He, Nan ShengWith the development of biotechnology and the accumulation of theories, many studies have found that microRNAs (miRNAs) play an important role in various diseases. Uncovering the potential associations between miRNAs and diseases is helpful to better understand the pathogenesis of complex diseases. However, traditional biological experiments are expensive and time-consuming. Therefore, it is necessary ...
-
Understanding the leaching behavior of calcium molybdate through the construction of lgc—pH diagramsJournal of Central South University (IF 2.392) Pub Date : 2023-03-23 ,DOI:10.1007/s11771-023-5240-9Wen-juan Zhang, Jian-yong Che, Ji-nian Zhu, Guo-ju Chen, Liu Xia, Jun Chen, Cheng-yan WangCaMoO4 is not only the main component of powellite, but also a key intermediate product in molybdenum metallurgy. The current leaching of CaMoO4 is mainly in experimental and industrial research, and seldom in theoretical analysis. In this research, lgc - pH diagrams for Ca-Mo-H2O, Ca-Mo-PO4-H2O, Ca-Mo-SiO4-H2O, Ca-Mo-CO3-H2O, Ca-Mo-Y(EDTA)-H2O, and Ca-Mo-F-H2O systems were constructed to predict the ...
-
CA916798 predicts poor prognosis and promotes Gefitinib resistance for lung adenocarcinomaBMC Cancer (IF 4.638) Pub Date : 2023-03-23 ,DOI:10.1186/s12885-023-10735-3Jian He, Xi Lan, Xiayan Liu, Caixia Deng, Hu Luo, Yan Wang, Ping Kang, Zhijian Sun, Lintao Zhao, Xiangdong ZhouOur previous studies have identified CA916798 as a chemotherapy resistance-associated gene in lung cancer. However, the histopathological relevance and biological function of CA916798 in lung adenocarcinoma (LUAD) remains to be delineated. In this study, we further investigated and explored the clinical and biological significance of CA916798 in LUAD. The relationship between CA916798 and clinical ...
-
Study on the mechanism and pharmacokinetics of HB-NC4 based on C5b-9 target in the treatment of osteoarthritisBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (IF 6.633) Pub Date : 2023-03-23 ,DOI:10.1016/j.bbadis.2023.166699Chai Rongrong, Yu Xueting, Li Lian, Wei Qiang, Jiao Guangjun, Li Ying, Yu Chen, Mu Yanling, Yao Qingqiang, Li Yan, Wang FuwenOsteoarthritis (OA) is a chronic degenerative disease that mostly occurs in elderly individuals over 60 years old. The detailed pathogenesis of OA is unclear. Medicines available on the market are nonsteroidal anti-inflammatory drugs. Therefore, in this study, a fusion protein was introduced, and the detailed mechanism that could alleviate OA was discussed. As a targeted protein, HB-NC4 showed better ...
-
Copper-Catalyzed Asymmetric Allylic Alkylation of Racemic Inert Cyclic Allylic Ethers under Batch and FlowChemical Science (IF 9.969) Pub Date : 2023-03-22 ,DOI:10.1039/d3sc00127jJun Li, Xiao Song, Yan Wang, Junrong Huang, Hengzhi You, Fener ChenHighly enantioselective Cu-catalyzed asymmetric allylic alkylation of racemic inert cyclic allylic ethers is accomplished in this work. The use of Grignard reagents in combination with BF3·OEt2 and CuBr·SMe2/L2 is the key to enable employment of long-challenging low reactive allylic substrates in this AAA reaction. In addition, the approach exhibited a remarkable superiority in the construction of ...
-
Luteolin restored Treg/Th17 balance to ameliorate allergic rhinitis in a mouse modelImmunopharmacology and Immunotoxicology (IF 3.712) Pub Date : 2023-03-22 ,DOI:10.1080/08923973.2023.2166527Yuping Yang, Lingling Wang, Song Wang, Yan Wang, Yunqiang Du, Yuqin FanAbstract Objective Luteolin (LO) has been reported to be a potential drug for allergic rhinitis (AR). This paper explored the mechanism of LO in AR. Materials and methods Mice were treated with ovalbumin (OVA) to construct an AR model in vivo before LO or 3-methyladenine (3-MA) treatment. The frequency of nasal sneezing was counted. The nasal mucosa thickness was assessed by hematoxylin–eosin staining ...
-
Small hollow ternary composite oxide semiconductor nanomaterials for conductometric HCHO sensorsSensors and Actuators B: Chemical (IF 9.221) Pub Date : 2023-03-22 ,DOI:10.1016/j.snb.2023.133703Lanlan Guo, Yuanyuan Wang, Yanji Feng, Hua Zeng, Xiaolian Liu, Yonghao Xu, Xueli Yang, Guodong Wang, Yan WangIn this work, the simple solvothermal method is adopted to synthesize nanometer sized hollow ternary composites of Pd@ZnO-SnO2 by using the protective effect of PVP molecules and ZIF-8 templates. The corresponding characterization such as SEM, XRD, XPS, TEM and HRTEM are employed to confirm the nanostructures, compositions and element distributions. Unlike other composites based on SnO2, the sensing ...
-
Fine Electron and Phonon Transports Manipulation by Mn Compensation for High Thermoelectric Performance of Sb2Te3(SnTe)n MaterialsMaterials Today Physics (IF 11.021) Pub Date : 2023-03-22 ,DOI:10.1016/j.mtphys.2023.101055Junchao Xia, Yi Huang, Xiao Xu, Yong Yu, Yan Wang, Kaitong Sun, Dasha Mao, Yitao Jiao, Hai-Feng Li, Jiaqing HeFabricating the Sb2Te3(SnTe)n compound has been proved as an effective way to suppress the lattice thermal conductivity and optimize the band structure simultaneously for enhancing the thermoelectric (TE) performance of SnTe. In view of the ultra-low carrier mobility resulted from the strong vacancy-electron scattering in SnTe-Sb2Te3 alloy, an appropriate weakening of vacancy scattering to pursue ideal ...
-
A novel probabilistic linguistic multi-attribute decision-making method based on Mahalanobis–Taguchi system and fuzzy measureJournal of the Operational Research Society (IF 3.051) Pub Date : 2023-03-21 ,DOI:10.1080/01605682.2023.2188888Mingzhen Zhang, Naiding Yang, Xianglin Zhu, Yan WangAbstract Probabilistic linguistic term sets (PLTSs) may convey flexible and accurate qualitative information to decision-makers, and it has been widely utilized to handle multi-attribute decision-making (MADM) issues. This article presents a novel technique for MADM using probabilistic linguistic information where attribute weights are entirely unknown and interactive. Firstly, we define the covariance ...
-
Migration, solidification/stabilization mechanism of heavy metal in lightweight ceramisite from co-sintering fly ash and electrolytic manganese residueProcess Safety and Environmental Protection (IF 7.926) Pub Date : 2023-03-21 ,DOI:10.1016/j.psep.2023.03.047Xinyuan Zhan, Yan Wang, Li’ao Wang, Chenxuan Li, Xiaowei Xu, Rui DengMunicipal solid waste incineration (MSWI) fly ash and electrolytic manganese residue, as hazardous waste, were roasted into lightweight ceramisite with coal fly ash. The migration, transformation and stabilization/solidification mechanism of heavy metals during ceramisite formation process was explored. Heavy metals in ceramisite pellet were concentrated and experienced the transportation among solids ...
-
Mixed methods evaluation of an oral health education program for pediatric dental, medical and nursing providersJournal of Dental Education (IF 2.313) Pub Date : 2023-03-21 ,DOI:10.1002/jdd.13199Francisco Ramos Gomez, Janni J. Kinsler, Laurie Love-Bibbero, Cambria Garell, Yan Wang, Nancy A. PikeTo evaluate the application of knowledge, attitudes, and skills learned in an oral health education program among pediatric dental and medical residents, and pediatric and family nurse practitioners (PNPs and FNPs). ...
-
Failure mechanisms and acoustic emission pattern recognition of all-CFRP cylindrical honeycomb sandwich shell under three-point bendingComposites Science and Technology (IF 9.879) Pub Date : 2023-03-21 ,DOI:10.1016/j.compscitech.2023.110003Zhibin Li, Ying Gao, Yan Wang, Pengcheng Xue, Cheng Gong, Wenyu Wang, Xingyu Wei, Jian XiongThe winding-based method is used for fabricating all carbon fiber reinforced plastic(CFRP) cylindrical honeycomb sandwich shell. The theoretical model of multi-failure modes of the cylindrical honeycomb sandwich shell is established under three-point bending. The multiple failure mechanisms of the honeycomb sandwich shell under three-point bending are revealed by the established three-dimensional failure ...
-
β-cyclodextrin-scaffolded crosslinked poly(ionic liquid)s for ultrafast removal of multiple pollutants: Insight into adsorption performance and mechanismChemical Engineering Journal (IF 16.744) Pub Date : 2023-03-21 ,DOI:10.1016/j.cej.2023.142526Jing Chen, Chunyang Bao, Mengshi Chen, Yan Wang, Xiaoling Xu, Tao Yang, Cenyao Shang, Qiang ZhangThe design of highly rapid and efficient cross-linked polymer materials is essential for developing adsorption of pollutant methods based on cyclodextrin to replace currently used slow trapping activated carbons. It is rarely possible to achieve rapid and complete adsorption at high concentrations, even though available adsorbents have developed high adsorption capacity. Herein, a beta-cyclodextrin ...
-
Rates of age verification for cigarette and e-cigarette purchases as a function of state T21 laws before and after implementation of the federal T21 law in the United States.Nicotine & Tobacco Research (IF 5.825) Pub Date : 2023-03-21 ,DOI:10.1093/ntr/ntad044Katelyn F Romm,Yan Wang,Nina C Schleicher,Alexandria Pannel,River Williams,Carla J Berg,Lisa HenriksenBACKGROUND This study examined the extent to which having a 21 minimum legal sales age for tobacco (T21) at the state level impacted age verification of cigarette and e-cigarette purchases among US young adults (ages 18-26) before and after federal T21 implementation. METHODS We analyzed data from cigarette and/or e-cigarette users (n=618 and n=864) in 6 metropolitan areas in 6 states. Participants ...
-
Stiff Extracellular Matrix Promotes Invasive Behaviors of Trophoblast CellsBioengineering Pub Date : 2023-03-21 ,DOI:10.3390/bioengineering10030384Jialing Cao, Hangyu Li, Hongyan Tang, Xuenan Gu, Yan Wang, Dongshi Guan, Jing Du, Yubo Fan
The effect of extracellular matrix (ECM) stiffness on embryonic trophoblast cells invasion during mammalian embryo implantation remains largely unknown. In this study, we investigated the effects of ECM stiffness on various aspects of human trophoblast cell behaviors during cell–ECM interactions. The mechanical microenvironment of the uterus was simulated by fabricating polyacrylamide (PA) hydrogels
...
-
Efficient Decision-based Black-box Patch Attacks on Video RecognitionarXiv - CS - Computer Vision and Pattern Recognition Pub Date : 2023-03-21 ,DOI:arxiv-2303.11917Kaixun Jiang, Zhaoyu Chen, Tony Huang, Jiafeng Wang, Dingkang Yang, Bo Li, Yan Wang, Wenqiang ZhangAlthough Deep Neural Networks (DNNs) have demonstrated excellent performance, they are vulnerable to adversarial patches that introduce perceptible and localized perturbations to the input. Generating adversarial patches on images has received much attention, while adversarial patches on videos have not been well investigated. Further, decision-based attacks, where attackers only access the predicted ...
-
Self-facial expression recognition training for children with autism spectrum disorders can improve their other-facial expression recognitionInternational Journal of Developmental Disabilities (IF 2.17) Pub Date : 2023-03-20 ,DOI:10.1080/20473869.2023.2190139Fuxin Lian, Yan Wang, Yun QinPrevious studies found that exposure to self-facial expressions (SFE) facilitated recognition of other-facial expressions (OFE) in typical individuals. However, this effect is unclear for individuals with autism spectrum disorder (ASD). This study designed an SFE recognition training curriculum and employed a nonconcurrent multiple probe-baseline design across participants to assess the effects of ...
-
Micro-CT characterization on pore structure evolution of low-permeability sandstone under acid treatmentApplied Geochemistry (IF 3.841) Pub Date : 2023-03-20 ,DOI:10.1016/j.apgeochem.2023.105633Sinan Liu, Liwei Zhang, Xuebin Su, Lixin Zhao, Yan WangPermeability enhancement via acid has drawn broad attention in mining and oil industries to treat low-permeability formations to increase the resource recovery rate. In this study, experiments including static acid permeability enhancement tests, flooding acid permeability enhancement tests, and micro-CT scanning were conducted to investigate the mechanism of permeability enhancement and changes in ...
-
Nanoporous Mixed-Phase In2O3 Nanoparticle Homojunctions for Formaldehyde SensingACS Applied Nano Materials (IF 6.14) Pub Date : 2023-03-20 ,DOI:10.1021/acsanm.3c00058Cong Qin, Yongjie Zhang, Yan Wang, Yan Zhang, Jianliang CaoDesigning a reliable sensor for indoor formaldehyde (HCHO) with high sensitivity and selectivity is crucial for environmental and health protection. This study reported HCHO sensors based on a nanoporous mixed-phase In2O3 nanoparticle. A combined cubic and orthorhombic phase In(OH)3/InOOH [c-In(OH)3/o-InOOH] precursor, synthesized through a facile solvothermal route at different temperatures, was annealed ...
-
Covalent binding modes between BMP-2-derived peptides and graphene in 3D scaffolds determine their osteoinductivity and capacity for calvarial defect repair in vivoInternational Journal of Biological Macromolecules (IF 8.025) Pub Date : 2023-03-20 ,DOI:10.1016/j.ijbiomac.2023.124077Zhiwei Xu, Cunyang Wang, Guiqin Song, Yan Wang, Xiaoyun Zhang, Xiaoming LiCovalent introduction of bioactive molecules is one of main strategies to significantly enhance the biological activities of bone repair materials. In this study, three most-commonly used chemical groups were respectively introduced on graphene (GP), followed by covalent binding with bone morphogenetic protein-2 (BMP-2) -derived peptides, ensuring that the same molar mass of peptides was bound to different ...
-
Leptin and leptin receptor expression as biomarkers for breast cancer: a retrospective studyBMC Cancer (IF 4.638) Pub Date : 2023-03-20 ,DOI:10.1186/s12885-023-10617-8Yan Wang, Lili Du, Jiexian Jing, Xianwen Zhao, Xing Wang, Shenghuai Hou
Effective screening and treatment have reduced the number of women dying from breast cancer (BC). However, the long-term sequelae of BC treatment and psychosocial factors seriously affect the life quality of BC patients and survivors. Therefore, the discovery and application of targeted biomarkers to improve the functional outcome and life quality of BC patients is necessary. To explore the impact
...
-
Identification of potential molecular mechanisms and candidate drugs for radiotherapy- and chemotherapy-induced mucositisSupportive Care in Cancer (IF 3.359) Pub Date : 2023-03-20 ,DOI:10.1007/s00520-023-07686-7Siyuan Hao, Yixin Jin, Yue Yu, Jiantao Wang, Jing Zou, Yan WangBackground Radiotherapy-induced oral mucositis (RIOM) and chemotherapy-induced oral mucositis (CIOM) are common complications in cancer patients, leading to negative clinical manifestations, reduced quality of life, and unsatisfactory treatment outcomes. Objective The present study aimed to identify potential molecular mechanisms and candidate drugs by data mining. Methods We obtained a preliminary ...
-
Abscopal effect triggered by radiation sequential mono-immunotherapy resulted in a complete remission of PMMR sigmoid colon cancerFrontiers in Immunology (IF 8.786) Pub Date : 2023-03-20 ,DOI:10.3389/fimmu.2023.1139527Pu Zhou, Yan Wang, Si Qin, Yan Han, Yumeng Yang, Liang Zhao, Quan Zhou, Wenlei Zhuo
BackgroundRadiation therapy combined with immune checkpoint inhibitors (ICIs) has recently turned into an appealing and promising approach to enhance the anti-tumor immunity and efficacy of immunological drugs in many tumors. Abscopal effect induced by radiation is a phenomenon that often leads to an efficient immunity response. In this study, we investigated whether the combination of the immunogenic
...
-
Mechanistic role of Mn heterogeneity in austenite decomposition and stabilization in a commercial quenching and partitioning steelActa Materialia (IF 9.209) Pub Date : 2023-03-20 ,DOI:10.1016/j.actamat.2023.118869Ran Ding, Chaofan Zhang, Yan Wang, Chenxi Liu, Yingjie Yao, Jun Zhang, Zhigang Yang, Chi Zhang, Yongchang Liu, Hao ChenManipulating chemical heterogeneity, which could substantially alter austenite decomposition behavior upon cooling, has recently proven to be very effective in tailoring retained austenite and architecting novel microstructures in steels. However, the mechanistic role of chemical heterogeneity in austenite decomposition and stabilization has not been fully understood, and its potential in microstructural ...
-
Analysis of the Mechanism Underlying Diabetic Wound Healing Acceleration by Calycosin-7-glycoside Using Network Pharmacology and Molecular DockingPhytomedicine (IF 6.656) Pub Date : 2023-03-20 ,DOI:10.1016/j.phymed.2023.154773Jia Chen, Huike Ma, Yujiao Meng, Qingwu Liu, Yan Wang, Yan Lin, Danyang Yang, Wentao Yao, Yazhuo Wang, Xiujuan He, Ping LiBackground Diabetic wounds represent a severe clinical challenge in which impaired M2 macrophage polarization and continuous macrophage glycolysis play crucial roles. Calycosin-7-glucoside (CG) is an isoflavone component in Astragali Radix (AR), which has become a research focus for treating diabetic wounds following reports indicating that it has anti-inflammatory effects. However, the mechanism through ...
-
Nab-paclitaxel and gemcitabine plus camrelizumab and radiotherapy versus nab-paclitaxel and gemcitabine alone for locally advanced pancreatic adenocarcinoma: a prospective cohort studyJournal of Hematology & Oncology (IF 23.168) Pub Date : 2023-03-20 ,DOI:10.1186/s13045-023-01422-8Shuling Chen, Jiaxin Li, Aoran Dong, Zelong Liu, Meiyan Zhu, Meng Jin, Guangyan Wei, Shuang Wu, Yan Wang, Yong Chen, Zhenwei PengTreatment options specifically for patients with locally advanced pancreatic adenocarcinoma (LAPC) are scare and chemotherapy alone delivers limited efficacy. Immunotherapy and radiotherapy are potential effective treatments for LAPC, and both of them may synergize with chemotherapy. Therefore, in this prospective cohort study, we compared the efficacy and safety of nab-paclitaxel plus gemcitabine ...
-
VIMI: Vehicle-Infrastructure Multi-view Intermediate Fusion for Camera-based 3D Object DetectionarXiv - CS - Computer Vision and Pattern Recognition Pub Date : 2023-03-20 ,DOI:arxiv-2303.10975Zhe Wang, Siqi Fan, Xiaoliang Huo, Tongda Xu, Yan Wang, Jingjing Liu, Yilun Chen, Ya-Qin ZhangIn autonomous driving, Vehicle-Infrastructure Cooperative 3D Object Detection (VIC3D) makes use of multi-view cameras from both vehicles and traffic infrastructure, providing a global vantage point with rich semantic context of road conditions beyond a single vehicle viewpoint. Two major challenges prevail in VIC3D: 1) inherent calibration noise when fusing multi-view images, caused by time asynchrony ...
-
The PRMT6/PARP1/CRL4B Complex Regulates the Circadian Clock and Promotes Breast TumorigenesisAdvanced Science (IF 17.521) Pub Date : 2023-03-20 ,DOI:10.1002/advs.202202737Tianshu Yang, Wei Huang, Tianyu Ma, Xin Yin, Jingyao Zhang, Miaomiao Huo, Ting Hu, Tianyang Gao, Wei Liu, Die Zhang, Hefen Yu, Xu Teng, Min Zhang, Hao Qin, Yunkai Yang, Baowen Yuan, Yan WangCircadian rhythms, as physiological systems with self-regulatory functions in living organisms, are controlled by core clock genes and are involved in tumor development. The protein arginine methyltransferase 6 (PRMT6) serves as an oncogene in a myriad of solid tumors, including breast cancer. Hence, the primary aim of the current study is to investigate the molecular mechanisms by which the PRMT6 ...
-
Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLYNature Communications (IF 17.694) Pub Date : 2023-03-20 ,DOI:10.1038/s41467-023-37279-1Shivesh Kumar, Yan Wang, Ye Zhou, Lucas Dillard, Fay-Wei Li, Carly A. Sciandra, Ning Sui, Rodolfo Zentella, Emily Zahn, Jeffrey Shabanowitz, Donald F. Hunt, Mario J. Borgnia, Alberto Bartesaghi, Tai-ping Sun, Pei Zhou
SPINDLY (SPY) in Arabidopsis thaliana is a novel nucleocytoplasmic protein O-fucosyltransferase (POFUT), which regulates diverse developmental processes. Sequence analysis indicates that SPY is distinct from ER-localized POFUTs and contains N-terminal tetratricopeptide repeats (TPRs) and a C-terminal catalytic domain resembling the O-linked-N-acetylglucosamine (GlcNAc) transferases (OGTs). However
...
广告：喜“文”乐“荐”|邀请好友使用Taylor & Francis Editing Services编辑润色服务，共享专属优惠！推荐人数无限制！
共有超过10000个结果符合您的查询条件，只显示了前300个，请优化您的查询条件，以获取更精确的结果。
高级搜索
我的搜索条件
京公网安备 11010802027423号