- 作 者: "yun chen"
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Oxidation of nickel in solid oxide cells during electrochemical operation: Experimental evidence, theoretical analysis, and an alternative hypothesis on the nickel migrationJournal of Power Sources (IF 9.794) Pub Date : 2023-03-31 ,DOI:10.1016/j.jpowsour.2023.232991Tian-Le Cheng, Yinkai Lei, Yun Chen, Yueying Fan, Harry Abernathy, Xueyan Song, You-Hai WenSolid oxide cells with nickel/yttrium-stabilized zirconia (Ni/YSZ) cermet electrodes exhibit Ni migration which can cause severe cell performance degradation. The experimentally reported migration behavior of Ni is complicated, and the mechanisms remain under debate. This work discusses the possible mechanism of Ni migration related to the oxidation of Ni at the Ni-electrolyte interfaces under polarization ...
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Predicting the short-term electricity demand based on the weather variables using a hybrid CatBoost-PPSO modelJournal of Building Engineering (IF 7.144) Pub Date : 2023-03-30 ,DOI:10.1016/j.jobe.2023.106432Liangli Zhang, Yun Chen, Zhongzhen YanIn this study, by using the capabilities of the CatBoost model and meta-heuristic algorithms, as well as the hybridization technique, an attempt was made to improve the prediction of electricity demand on a short-term scale. For this purpose, the hybrid CatBoost-PPSO model was suggested in this study to predict electricity demand based on weather variables. Finally, by conducting a case study and comparing ...
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Reducing interfacial thermal resistance between epoxy and alumina via interfacial engineeringPhysica Status Solidi (A) - Applications and Materials Science (IF 2.17) Pub Date : 2023-03-30 ,DOI:10.1002/pssa.202200800Wei Yang, Mengtao Zhang, Kun Wang, Jian Qiao, Yun Chen, Fangyuan Sun, Kun Zheng, Yushun Zhao, Daili FengEpoxy composites are increasingly employed in the information industry fields, where the interfacial thermal resistance of polymer/nanofiller is considered to be one of the most important factors affecting the thermal conductivity of polymer composites. Here, the interfacial thermal resistance with different functionalized aluminas and epoxy is first investigated by molecular dynamics. The functional ...
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Constructed Tumor-Targeted and MMP-2 Biocleavable Antibody Conjugated Silica Nanoparticles for Efficient Cancer TherapyACS Omega (IF 4.132) Pub Date : 2023-03-29 ,DOI:10.1021/acsomega.2c07949Hao Wu, Xuefeng Ding, Yun Chen, Yanfei Cai, Zhaoqi Yang, Jian JinAntibody–drug conjugates (ADC) are an inevitable trend in the development of modern “precision medicine”. The goal of this work is to produce enzyme-responsive antibody nanoparticle-loaded medication (FMSN-Dox-H2-AE01) based on the EGFR antibody (AE01) and human serum albumin (HSA) shelled mesoporous silica nanoparticles. HSA and antibodies on the surface of the particlescan not only enhance the biocompatibility ...
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Design of BODIPY functional ZIF-90 towards enhanced visible-light driven antibacterial performanceNew Journal of Chemistry (IF 3.925) Pub Date : 2023-03-29 ,DOI:10.1039/d3nj00397cDong-Mei Chen, Guang-Qi He, Qiu-Yun Chen, Gaoji Wang, Cheng Chen, Ying Dong, Lingling QuDeveloping novel antibacterial materials and therapeutic strategy to combat multidrug-resistant bacteria are currently very active research area. Photoactivation nano-antibacterial agents have attracted more and more interest because of their multimodal antibacterial effect and no drug resistance. In this study, a novel visible light-activated antibacterial composite (BODIPY- ZIF-90) is synthetized ...
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Single-cell RNA sequencing depicts metabolic changes in children with aplastic anemiaFrontiers in Oncology (IF 5.738) Pub Date : 2023-03-29 ,DOI:10.3389/fonc.2023.1075408Qin Zhou, Lifen Huang, Yong Liu, Junbin Huang, Luping Wen, Jing Yang, Jintang Liang, Yun Chen, Chun Chen
IntroductionAplastic anemia (AA) is a bone marrow hematopoietic failure syndrome mediated by immune cells. The mechanism of this immune disorder is not well understood and therapeutic strategies still need to be improved.MethodsStudies have found that abnormalities in metabolisms promote the survival of AA cells. In recent years, an increasing number of studies have reported the immunosuppressive therapy
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Comprehensive ab initio study of effects of alloying elements on generalized stacking fault energies of Ni and Ni$_3$AlarXiv - PHYS - Materials Science Pub Date : 2023-03-29 ,DOI:arxiv-2303.16379Heyu Zhu, Jiantao Wang, Yun Chen, Mingfeng Liu, Hui Ma, Yan Sun, Peitao Liu, Xing-Qiu ChenExcellent high-temperature mechanical properties of Ni-based single crystal superalloys (NSCSs) are attributed to the yield strength anomaly of Ni$_{3}$Al that is intimately related to generalized stacking fault energies (GSFEs). Therefore, clarifying the effects of alloying elements on the GSFEs is of great significance for alloys design. Here, by means of ab initio density functional theory calculations ...
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Highly effective interlayer expanded MoS2 coupled with Bi2WO6 as p-n heterojunction photocatalyst for photodegradation of organic dye under LED white lightJournal of Alloys and Compounds (IF 6.371) Pub Date : 2023-03-28 ,DOI:10.1016/j.jallcom.2023.169834Magdeline Tze Leng Lai, Kian Mun Lee, Thomas Chung Kuang Yang, Chin Wei Lai, Chia-Yun Chen, Mohd Rafie Johan, Joon Ching JuanThe construction of a p-n heterojunction photocatalyst manage to conquer the setbacks of low photocatalytic activity caused by rapid charge recombination and precarious photo-response range. Herein, an interlayer of expanded MoS2 coupled with Bi2WO6 (BW-IEM) photocatalyst was synthesized for removal of Methylene Blue (MB) up to 97% (5.18 ×10-2 min-1) under irradiation of low power 1 W LED white light ...
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Status quo of the public’s knowledge of probiotics based on video-sharing platformsBMC Public Health (IF 4.135) Pub Date : 2023-03-28 ,DOI:10.1186/s12889-023-15456-7Chun-Hui Jiang, Jia-Jia Xu, Chao Xu, Shi-Yue Chen, Jia-Yun Chen, Jing-Song Xia, Zhuan Liao, Wen-Bin Zou, Xue FangProbiotics have been deemed multipotent and unprecedentedly applied in the health field recently. However, there are challenges in promoting credible and reliable resources while avoiding misinformation regarding probiotics for the public. This study analysed 400 eligible probiotic-related videos selected from YouTube, and the three most popular video-sharing platforms (Bilibili, Weibo and TikTok) ...
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Experimental Twin-Field Quantum Key Distribution Over 1000 km Fiber DistancearXiv - PHYS - Quantum Physics Pub Date : 2023-03-28 ,DOI:arxiv-2303.15795Yang Liu, Wei-Jun Zhang, Cong Jiang, Jiu-Peng Chen, Chi Zhang, Wen-Xin Pan, Di Ma, Hao Dong, Jia-Min Xiong, Cheng-Jun Zhang, Hao Li, Rui-Chun Wang, Jun Wu, Teng-Yun Chen, Lixing You, Xiang-Bin Wang, Qiang Zhang, Jian-Wei PanQuantum key distribution (QKD) aims to generate secure private keys shared by two remote parties. With its security being protected by principles of quantum mechanics, some technology challenges remain towards practical application of QKD. The major one is the distance limit, which is caused by the fact that a quantum signal cannot be amplified while the channel loss is exponential with the distance ...
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Integrated high-sulfur-loading polysulfide/carbon cathode in lean-electrolyte cell toward high-energy-density lithium–sulfur cells with stable cyclabilityJournal of Materials Chemistry A (IF 14.511) Pub Date : 2023-03-27 ,DOI:10.1039/d3ta00210aYun-Chen Wu, Sheng-Heng ChungThe commercialization of high-energy-density lithium–sulfur batteries depends on the development of a high-sulfur-loading cathode with high electrochemical utilization and stability in lean-electrolyte cells. However, the desired cell-design parameters often exacerbate the sluggish conversion reaction between sulfur and sulfide and intensify polysulfide diffusion. This results in low specific capacity ...
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Variability of blood pressure and risk of postoperative acute kidney injury in patients undergoing surgery for acute aortic dissection: A 11-year single-center studyJournal of Clinical Hypertension (IF 2.885) Pub Date : 2023-03-27 ,DOI:10.1111/jch.14654Yan Li, Tingting Zheng, Jianfei Zhu, Yanjun Chen, Yun Chen, Shuai SunIn patients receiving surgery, increased blood pressure variability may contribute to the onset of acute kidney injury (AKI). However, the extent and significance of blood pressure variability in patients undergoing aortic dissection surgery have yet to be determined. The authors analyzed all patients operated for aortic dissection at Peking University Shenzhen Hospital from January 1, 2011 to December ...
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Frontier Review of the Molecular Mechanisms and Current Approaches of Stem Cell-Derived ExosomesCells (IF 7.666) Pub Date : 2023-03-26 ,DOI:10.3390/cells12071018Liang-Yun Chen, Ting-Wan Kao, Chang-Cyuan Chen, Noreen Niaz, Hsin-Lun Lee, Yu-Hsin Chen, Chia-Chun Kuo, Yao-An ShenExosomes are effective therapeutic vehicles that may transport their substances across cells. They are shown to possess the capacity to affect cell proliferation, migration, anti-apoptosis, anti-scarring, and angiogenesis, via the action of transporting molecular components. Possessing immense potential in regenerative medicine, exosomes, especially stem cell-derived exosomes, have the advantages of ...
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Development of NS2B-NS3 protease inhibitor that impairs Zika virus replication.Virus research Pub Date : 2023-03-23 ,DOI:10.1016/j.virusres.2023.199092Wen-Wei Lin,Yi-Jung Huang,Yen-Tseng Wang,Yun-Syuan Lin,Nonsikelelo Mazibuko,Chien-Shu Chen,Tian-Lu Cheng,Chih-Shiang Chang,Yu-Ling Leu,Chiao-Yun Chen,Chih-Hung ChuangZika virus (ZIKV) is a mosquito-borne flavivirus that causes severe neurological disorders, such as microcephaly in fetuses. Most recently, an outbreak of ZIKV started in Brazil in 2015. To date, no therapeutic agents have been approved to treat ZIKV infection in the clinic. Here, we screened a small molecule inhibitor that can inhibit the function of ZIKV non-structural protein 2B (NS2B)-NS3 protease ...
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The Effect of Various Fillers on the Properties of Methyl Vinyl Silicone RubberPolymers (IF 4.967) Pub Date : 2023-03-22 ,DOI:10.3390/polym15061584Yun Chen, Kun Wang, Chong Zhang, Wei Yang, Bo Qiao, Li Yin
Silicone rubber (SIR) has been widely used in electrical insulation fields, and the introduction of new materials is very important for the performance improvement of SIR composites. In this work, four different fillers, including aluminium hydroxide (ATH), yimonite (YMT), boron nitride (BN) and mica-filled SIR composites were prepared, and the vulcanization behavior, mechanical properties, insulation
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Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathwaysPsychopharmacology (IF 4.415) Pub Date : 2023-03-22 ,DOI:10.1007/s00213-023-06357-zDehua Liao, Danggang Shangguan, Yi Wu, Yun Chen, Ni Liu, Jingyi Tang, Dunwu Yao, Yingrui Shi
Background Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies. Oxidative stress has been validated as a critical event involved in DOX-induced neurotoxicity. As a selective autophagy adaptor protein, p62 is reported to regulate Keap1-Nrf2-ARE antioxidant pathway in response to oxidative stress. Curcumin (CUR) relieves depressive-like state through the mitigation of oxidative
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Structural Effects of Microcrystalline Cellulose-Derived Carbon Supports on Catalytic Performance of the Pd(OH)2/C Catalysts for the Hydrogenolytic Debenzylation of Hexanitrohexaazaisowurtzitane DerivativesCatalysts (IF 3.52) Pub Date : 2023-03-22 ,DOI:10.3390/catal13030637Yuling Wang, Yun Chen, Xinlei Ding, Jianwei Song, Gaixia Wei, Hengwei Dai, Hanyang Wang, Yadong Liu, Guangmei Bai, Wenge Qiu
In order to reduce the noble metal palladium dosage in the preparation of CL-20 so as to reduce its production cost, several carbon supports were prepared successfully using the hydrothermal carbonization method in the absence or presence of urea using microcrystalline cellulose (MC) as the carbon source, and the corresponding Pd(OH)2/C catalysts were fabricated using the deposition–precipitation method
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Real-time demonstration of a low-complexity PS scheme for 16QAM-DMT signals in an IM-DD systemOptics Express (IF 3.833) Pub Date : 2023-03-21 ,DOI:10.1364/oe.480741Long Zhang, Kaihui Wang, Chen Wang, Ming Chen, Junjie Ding, Bohan Sang, Junting Shi, Jiaxuan Liu, Mingxv Wang, Yi Wei, Yun Chen, Li Zhao, Wen Zhou, and Jianjun Yu
We experimentally demonstrated a low-complexity probabilistic shaping (PS) 16-ary quadrature amplitude modulation (16QAM) scheme based on intra-symbol bit-weighted distribution matching (Intra-SBWDM) for discrete multi-tone (DMT) symbols with field-programmable gate array implementation in an intensity modulation and direct detection (IM-DD) system. Different from the traditional PS scheme such as
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Real-time demonstration of a low-complexity PS scheme for 16QAM-DMT signals in an IM-DD systemOptics Express (IF 3.833) Pub Date : 2023-03-21 ,DOI:Long Zhang, Kaihui Wang, Chen Wang, Ming Chen, Junjie Ding, Bohan Sang, Junting Shi, Jiaxuan Liu, Mingxv Wang, Yi Wei, Yun Chen, Li Zhao, Wen Zhou, and Jianjun YuWe experimentally demonstrated a low-complexity probabilistic shaping (PS) 16-ary quadrature amplitude modulation (16QAM) scheme based on intra-symbol bit-weighted distribution matching (Intra-SBWDM) for discrete multi-tone (DMT) symbols with field-programmable gate array implementation in an intensity modulation and direct detection (IM-DD) system. Different from the traditional PS scheme such as ...
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Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelinationCell Reports (IF 9.995) Pub Date : 2023-03-21 ,DOI:10.1016/j.celrep.2023.112293Hou, Yingyue Zhou, Zhangying Cai, Marina Terekhova, Amanda Swain, Prabhakar S. Andhey, Rafaela M. Guimaraes, Alina Ulezko Antonova, Tian Qiu, Sanja Sviben, Gregory Strout, James A.J. Fitzpatrick, Yun Chen, Susan Gilfillan, Do-Hyun Kim, Steven J. Van Dyken, Maxim N. Artyomov, Marco ColonnaDemyelination is a hallmark of multiple sclerosis, leukoencephalopathies, cerebral vasculopathies, and several neurodegenerative diseases. The cuprizone mouse model is widely used to simulate demyelination and remyelination occurring in these diseases. Here, we present a high-resolution single-nucleus RNA sequencing (snRNA-seq) analysis of gene expression changes across all brain cells in this model ...
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Fabrication of recyclable magnetic Fe3O4–SiO2–Cu2O/Cu core–shell nano-catalyst for high-efficient reduction of aromatic nitro compoundJournal of Materials Science (IF 4.682) Pub Date : 2023-03-19 ,DOI:10.1007/s10853-023-08377-8Shanshan Sun, Zihao Zhang, Shuhan Li, Jinxun Le, Haixia Qian, Xiaoshuang Yin, Ying Liu, Wenzhong Yang, Yun ChenMagnetic core–shell nanomaterial Fe3O4–SiO2–Cu2O/Cu was first successfully synthesized using an economical strategy. Using Fe3O4 as a magnetic center for easy recycling and SiO2 as the connecting layer, Cu elements were evenly and steadily distributed on the surface of the Fe3O4–SiO2–Cu2O/Cu core–shell nanostructure. The magnetic catalyst performed outstanding catalytic reduction activity for 4-nitrophenol ...
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An equivalent analysis of non-linear flow along rough-walled fractures based on power spectrum and wavelet transformJournal of Hydrology (IF 6.708) Pub Date : 2023-03-17 ,DOI:10.1016/j.jhydrol.2023.129351Chunlei Ma, Yun Chen, Xiaoliang Tong, Guowei MaThe classical cubic law deviates from the estimation of the flow rate because of the surface roughness distributed along the fracture surface, which can be decomposed as the primary and the secondary roughness. A piecewise equivalent model is developed to characterise the relationship between primary and secondary roughness and flow rate inside the fracture, setting the fractal dimension 2.0 as the ...
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Corrigendum to “Co-folding of soy protein isolates and shellac by structural interplays to induce hydrogels” [Food Hydrocolloids 139 (2023) 108527]Food Hydrocolloids (IF 11.504) Pub Date : 2023-03-17 ,DOI:10.1016/j.foodhyd.2023.108686Yang Guo, Zhi-guo Zhang, Jing Cai, Wei-rong Li, Ling-yun Chen, Wei-cheng WuAbstract not available ...
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Chemometric-guided chemical marker selection: A case study of the heat-clearing herb Scrophularia ningpoensisFrontiers in Plant Science (IF 6.627) Pub Date : 2023-03-17 ,DOI:10.3389/fpls.2023.1153710Lung-Shuo Wang, Po-Jen Chen, Wen-Chi Cheng, Yu-Chia Chang, Mohamed El-Shazly, Lo-Yun Chen, Bo-Rong Peng, Chun-Han Su, Pei-Tzu Yen, Tsong-Long Hwang, Kuei-Hung Lai
The selection of medicinal plants’ chemical markers focuses on bioactivity as the primary goal, followed by the nature of secondary metabolites, their stability, and availability. However, herbal medicines are valued for their complex and holistic pharmacological effects. A correct chemical marker can be carefully selected by a systematic clarification of their chemical-biological relationships. In
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Triazine-based covalent organic framework/carbon nanotube fiber nanocomposites for high-performance supercapacitor electrodesPolymer (IF 4.432) Pub Date : 2023-03-16 ,DOI:10.1016/j.polymer.2023.125853Huan-Cheng Yang, Yi-Yun Chen, Shing-Yi Suen, Rong-Ho LeeIn this study we synthesized the triazine-based two-dimensional covalent organic frameworks (COFs) TPTP-COF and TPDA-COF through Schiff base (imine) condensations of 2,4,6-tris(4-formylphenyl)-1,3,5-triazine (TPT-3CHO) with 2,4,6-tris(4-aminophenyl)triazine (TPT-3NH2) and diaminoanthraquinone (DAAQ), respectively. Moreover, we used carbon nanotube fibers (f-CNFs) as a template to synthesize TPTP-COF@f-CNF ...
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Serine/threonine kinase TBK1 promotes cholangiocarcinoma progression via direct regulation of β-cateninOncogene (IF 8.756) Pub Date : 2023-03-16 ,DOI:10.1038/s41388-023-02651-4Chong-Qing Gao, Zhen-Zhen Chu, Di Zhang, Yang Xiao, Xing-Yan Zhou, Jun-Ru Wu, Hui Yuan, Yu-Chuan Jiang, Dong Chen, Ji-Chun Zhang, Nan Yao, Kai-Yun Chen, Jian Hong
Cholangiocarcinoma (CCA) is a highly heterogeneous and metastatic malignancy with a poor prognosis even after curative hepatectomy. Studies exploring its pathogenesis and identifying effective therapeutic targets are urgently needed. In this study, we found that TANK-binding kinase 1 (TBK1), a serine/threonine-protein kinase, showed a dynamic increase during the different stages of murine spontaneous
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Oral cavity-derived stem cells and preclinical models of jaw-bone defects for bone tissue engineeringStem Cell Research & Therapy (IF 8.079) Pub Date : 2023-03-16 ,DOI:10.1186/s13287-023-03265-zJie Zhao, Ying-Hui Zhou, Ya-Qing Zhao, Zheng-Rong Gao, Ze-Yue Ouyang, Qin Ye, Qiong Liu, Yun Chen, Li Tan, Shao-Hui Zhang, Yao Feng, Jing Hu, Marie Aimee Dusenge, Yun-Zhi Feng, Yue Guo
Jaw-bone defects caused by various diseases lead to aesthetic and functional complications, which can seriously affect the life quality of patients. Current treatments cannot fully meet the needs of reconstruction of jaw-bone defects. Thus, the research and application of bone tissue engineering are a “hot topic.” As seed cells for engineering of jaw-bone tissue, oral cavity-derived stem cells have
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Serine/threonine kinase TBK1 promotes cholangiocarcinoma progression via direct regulation of β-catenin.Oncogene Pub Date : 2023-03-16 ,DOI:10.1038/s41388-023-02651-4Chong-Qing Gao,Zhen-Zhen Chu,Di Zhang,Yang Xiao,Xing-Yan Zhou,Jun-Ru Wu,Hui Yuan,Yu-Chuan Jiang,Dong Chen,Ji-Chun Zhang,Nan Yao,Kai-Yun Chen,Jian HongCholangiocarcinoma (CCA) is a highly heterogeneous and metastatic malignancy with a poor prognosis even after curative hepatectomy. Studies exploring its pathogenesis and identifying effective therapeutic targets are urgently needed. In this study, we found that TANK-binding kinase 1 (TBK1), a serine/threonine-protein kinase, showed a dynamic increase during the different stages of murine spontaneous ...
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Remnant cholesterol and mild cognitive impairment: A cross-sectional studyFrontiers in Aging Neuroscience (IF 5.702) Pub Date : 2023-03-15 ,DOI:10.3389/fnagi.2023.1069076Qiaoyang Zhang, Shan Huang, Yin Cao, Guanzhong Dong, Yun Chen, Xuanyan Zhu, Wenwei Yun, Min Zhang
ObjectiveEmerging evidence suggests that elevated remnant cholesterol (RC) correlates with several health conditions. To explore the association of plasma RC with MCI incidence and the relationship between plasma RC and different domains of cognition in MCI patients.MethodsThirty-six MCI patients and 38 cognitively healthy controls (HC) were enrolled in the present cross-sectional study. Using total
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Anti-inflammatory cembrane-based diterpenoids isolated from the octocoral Sinularia querciformisPhytochemistry Letters (IF 1.873) Pub Date : 2023-03-15 ,DOI:10.1016/j.phytol.2023.03.004Te-An Kung, Lo-Yun Chen, Chia-Ying Li, Bo-Rong Peng, Tsong-Long Hwang, Ping-Jyun Sung, Kuei-Hung Lai, Hsu-Ming ChungThe exploration of Sinularia querciformis cembranoids afforded two new compounds, querciformolide G (1) and H (2), along with three known ones, sinulaparvalide (3), sinulariolone acetate (4), and 3,4:8,11-bisepoxy-7-hydroxycembra-15(17)-en-1,12-olide (5). The structural elucidation of these compounds was achieved by extensive spectroscopic (IR, ESIMS, 1D and 2D NMR data) analysis and by comparison ...
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