- 作 者: "Dixon, Darren"
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A Survey of the Operational Environment and Regulations of Hospital Owned Helipads at Level I Trauma CentersAir Medical Journal Pub Date : 2022-03-02 ,DOI:10.1016/j.amj.2021.08.018Amanda Ventura, Maggie O'Donnell, Doug Dixon, Darren BraudeIntroduction The Association of Air Medical Services (AAMS) estimates that 400,000 patients per year are transported by rotor wing aircraft. Despite the frequent utilization of air medical transport, little is known about the operational environment and regulations of hospital owned helipads. We sought to understand the environment and regulations of hospital helipads, hypothesizing that the majority ...
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Incidence of Paget's disease of bone in the UK: evidence of a continuing decline.Rheumatology (Oxford, England) Pub Date : 2021-12-01 ,DOI:10.1093/rheumatology/keab232Michael J Cook,Stephen R Pye,Mark Lunt,William G Dixon,Darren M Ashcroft,Terence W O'NeillOBJECTIVES To characterize the incidence of clinically diagnosed Paget's disease of bone in the UK during 1999-2015 and to determine variations in the incidence of disease by age, sex, geography and level of deprivation. METHODS Incident cases of Paget's disease occurring between 1999 and 2015 were identified from primary care records. Overall crude incidence and incidence stratified by age and sex ...
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Incidence of Paget’s disease of bone in the UK: evidence of a continuing declineRheumatology (IF 7.58) Pub Date : 2021-03-17 ,DOI:10.1093/rheumatology/keab232Michael J Cook, Stephen R Pye, Mark Lunt, William G Dixon, Darren M Ashcroft, Terence W O’NeillObjectives To characterize the incidence of clinically diagnosed Paget’s disease of bone in the UK during 1999–2015 and to determine variations in the incidence of disease by age, sex, geography and level of deprivation. Methods Incident cases of Paget’s disease occurring between 1999 and 2015 were identified from primary care records. Overall crude incidence and incidence stratified by age and sex ...
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Out-of-hospital extracorporeal membrane oxygenation cannulation for refractory ventricular fibrillation: A case report.Journal of the American College of Emergency Physicians open Pub Date : 2020-04-30 ,DOI:10.1002/emp2.12033Jon Marinaro,Sundeep Guliani,Todd Dettmer,Kimberly Pruett,Doug Dixon,Darren Braude
Out-of-hospital cardiac arrest survival continues to be dismal with the only recent improvement being that of extracorporeal cardiopulmonary resuscitation (E-CPR) or cardiopulmonary resuscitation (CPR), augmented by extracorporeal membrane oxygenation (ECMO). Minimizing time until initiation of E-CPR is critical to improve neurologically intact survival. Bringing E-CPR to the patient rather than requiring
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A qualitative analysis of patients’ reasons for choosing neobladder or ileal conduit after cystectomy for bladder cancerJournal of Clinical Urology Pub Date : 2016-07-08 ,DOI:10.1177/2051415816650841Lisa A Osborne, Catherine Dixon, Darren J Edwards, Rahima Begum, Ayman Younis, Malcolm Lucas, Phil Reed
Objective: Choice of reconstruction following bladder removal is often between neobladder or ileal conduit diversion. Identifying patient concerns about this little understood choice should provide better understanding of factors important in making surgical decisions. The current study used a qualitative technique to identify patient concerns and values influencing patient choice of bladder reconstruction
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THE BARIATRIC AIRWAY. It's not all about the intubation.JEMS : a journal of emergency medical services Pub Date : 2015-09-26 ,DOI:Douglas R Dixon,Darren BraudeIn airway procedures, preparation is 90% of success. For obese patients, positioning is 90% of this preparation. Other considerations include utilizing NIPPV and nasal cannula apneic oxygenation, utilizing multiple providers and airway adjuncts for BVM ventilation, correctly dosing medications based upon ideal, lean or total body weight, and having backup airway devices ready. ...
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Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor.FEBS letters. Pub Date : 2014 Jun 1 ,DOI:10.1016/j.febslet.2014.04.049Deenadayalan Bakthavatsalam,Roh Hun Soung,David J. Tweardy,Wah Chiu,Richard A.F. Dixon,Darren G. Woodside
Lectin-like oxidized low-density lipoprotein receptor (LOX-1) is a scavenger receptor that binds oxidized low-density lipoprotein (OxLDL) and has a role in atherosclerosis development. The N-terminus intracellular region (cytoplasmic domain) of LOX-1 mediates receptor internalization and trafficking, potentially through intracellular protein interactions. Using affinity isolation, we identified 6 of
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Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptorFEBS Letters (IF 4.124) Pub Date : 2014-05-17 ,DOI:10.1016/j.febslet.2014.04.049Deenadayalan Bakthavatsalam, Roh Hun Soung, David J. Tweardy, Wah Chiu, Richard A.F. Dixon, Darren G. Woodside
Lectin‐like oxidized low‐density lipoprotein receptor (LOX‐1) is a scavenger receptor that binds oxidized low‐density lipoprotein (OxLDL) and has a role in atherosclerosis development. The N‐terminus intracellular region (cytoplasmic domain) of LOX‐1 mediates receptor internalization and trafficking, potentially through intracellular protein interactions. Using affinity isolation, we identified 6 of
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miR‐1 and miR‐301a Overexpression Impairs Collagen Gel Contraction in Human Mesenchymal Stem CellsThe FASEB Journal (IF 5.191) Pub Date : 2012-04-01 ,DOI:10.1096/fasebj.26.1_supplement.lb681Jessica Rae Klassen,Shannon Neumann,Mina Guirgis,Melanie Ngo,Yun Li,Ian Dixon,Darren FreedSt. Boniface Research CenterWinnipegMBCanada
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All one-loop maximally helicity violating gluonic amplitudes in QCDPhysical Review D (IF 5.296) Pub Date : 2007-01-24 ,DOI:10.1103/physrevd.75.016006Carola F. Berger, Zvi Bern, Lance J. Dixon, Darren Forde, David A. Kosower
We use on-shell recursion relations to compute analytically the one-loop corrections to maximally-helicity-violating n-gluon amplitudes in QCD. The cut-containing parts have been computed previously; our work supplies the remaining rational parts for these amplitudes, which contain two gluons of negative helicity and the rest positive, in an arbitrary color ordering. We also present formulae specific
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Bootstrapping one-loop QCD amplitudes with general helicitiesPhysical Review D (IF 5.296) Pub Date : 2006-08-31 ,DOI:10.1103/physrevd.74.036009Carola F. Berger, Zvi Bern, Lance J. Dixon, Darren Forde, David A. Kosower
The recently developed on-shell bootstrap for computing one-loop amplitudes in non-supersymmetric theories such as QCD combines the unitarity method with loop-level on-shell recursion. For generic helicity configurations, the recursion relations may involve undetermined contributions from non-standard complex singularities or from large values of the shift parameter. Here we develop a strategy for
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Homography-based visual servo regulation of mobile robots.IEEE transactions on systems, man, and cybernetics. Part B, Cybernetics : a publication of the IEEE Systems, Man, and Cybernetics Society Pub Date : 2005-10-26 ,DOI:10.1109/tsmcb.2005.850155Yongchun Fang,Warren E Dixon,Darren M Dawson,Prakash ChawdaInstitute of Robotics and Automatic Information System, Nankai University, Tianjin, China.
A monocular camera-based vision system attached to a mobile robot (i.e., the camera-in-hand configuration) is considered in this paper. By comparing corresponding target points of an object from two different camera images, geometric relationships are exploited to derive a transformation that relates the actual position and orientation of the mobile robot to a reference position and orientation. This
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A 2,3-butanedione protected chiral glycine equivalent--a new building block for the stereoselective synthesis of enantiopure N-protected alpha-amino acids.Chemical Communications (IF 6.222) Pub Date : 2003 Feb 2 ,DOI:Dixon, Darren J, Harding, Christopher I, Ley, Steven V, Tilbrook, D Matthew GA new chiral glycine equivalent 7 has been synthesised from glycidol using a chiral memory protocol, and its use in the synthesis of N-Z protected alpha-amino acids was demonstrated in a series of diasteroselective lithium enolate alkylation reactions and subsequent acid hydrolyses. ...
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Synthesis, structure revision, and absolute configuration of (+)-didemniserinolipid B, a serinol marine natural product from a tunicate Didemnum sp.Organic Letters (IF 6.005) Pub Date : 2002 Sep 1 ,DOI:Kiyota, Hiromasa, Dixon, Darren J, Luscombe, Christine K, Hettstedt, Stephan, Ley, Steven V[structure: see text] En route to proving the absolute and relative stereochemistry, through synthesis, of (+)-didemniserinolipid B (1), the first natural serinolipid isolated from a tunicate Didemnum sp., it was discovered that the isolated natural product was in fact the 31-sulfate configured 8R,9R,10R,13S,30S. This structural reassignment was only possible after the development of a microwave-assisted ...
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Total synthesis of polycephalin C and determination of the absolute configurations at the 3",4" ring junction.Angewandte Chemie International Edition (IF 15.336) Pub Date : 2002 Aug 2 ,DOI:10.1002/1521-3773(20020802)41:15<2786::aid-anie278Longbottom, Deborah A, Morrison, Angus J, Dixon, Darren J, Ley, Steven V
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The total synthesis of the annonaceous acetogenin, muricatetrocin C.Chemistry - A European Journal (IF 5.236) Pub Date : 2002 Apr 2 ,DOI:Dixon, Darren J, Ley, Steven V, Reynolds, Dominic JThe total synthesis of the potential antitumour agent muricatetrocin C has provided an ideal stage for the exploitation and development of new chemistry. A convergent synthetic strategy has been realised incorporating three distinct pieces of methodology, these include a highly diastereoselective hetero-Diels-Alder reaction to construct the butenolide terminus, an oxygen to carbon rearrangement to ...
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Consecutive Three- and Four-Component Coupling Reactions with Anions Generated from a Butane Diacetal Desymmetrized Glycolic Acid Derivative We gratefully acknowledge financial support from the EPSRC (to D.J.D.), the EU (Marie Curie Fellowship to F.R.), and the Novartis Research Fellowship (to S.V.L.). We are also indebted to Dr. John E. Davis for the X-ray crystal structure determinations.Angewandte Chemie International Edition (IF 15.336) Pub Date : 2001 Dec 1 ,DOI:Dixon, Darren J., Ley, Steven V., Rodriguez, Felix
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Butane-2,3-Diacetal-Desymmetrized Glycolic Acid-A New Building Block for the Stereoselective Synthesis of Enantiopure alpha-Hydroxy Acids We thank the EU (Marie Curie Fellowship to E.D.), the EPSRC (to D.J.D.), the Novartis Research Fellowship (to S.V.L.), and Pfizer Gobal Research and Development, Groton, USA, for financial support.Angewandte Chemie International Edition (IF 15.336) Pub Date : 2001 Aug 3 ,DOI:Diez, Elena, Dixon, Darren J., Ley, Steven V.
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