- 作 者: "yu guo"
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Neural progenitor cells derived from fibroblasts induced by small molecule compounds under hypoxia for treatment of Parkinson's disease in rats.Neural Regeneration Research (IF 6.058) Pub Date : 2023-05-01 ,DOI:10.4103/1673-5374.355820Yu Guo,Yuan-Yuan Wang,Ting-Ting Sun,Jia-Jia Xu,Pan Yang,Cai-Yun Ma,Wei-Jun Guan,Chun-Jing Wang,Gao-Feng Liu,Chang-Qing Liu
Neural progenitor cells (NPCs) capable of self-renewal and differentiation into neural cell lineages offer broad prospects for cell therapy for neurodegenerative diseases. However, cell therapy based on NPC transplantation is limited by the inability to acquire sufficient quantities of NPCs. Previous studies have found that a chemical cocktail of valproic acid, CHIR99021, and Repsox (VCR) promotes
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Fixed time sliding mode control for disturbed robotic manipulatorJournal of Vibration and Control (IF 2.633) Pub Date : 2023-03-23 ,DOI:10.1177/10775463231165094Zeeshan Anjum, Hui Zhou, Saim Ahmed, Yu GuoIn this study, a new fixed-time sliding mode control approach for trajectory tracking control of robotic manipulator systems is devised, which provides fixed-time convergence, robust stabilization,... ...
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Prenatal exposure to corn oil, CMC-Na or DMSO affects physical development and multi-organ functions in fetal miceReproductive Toxicology (IF 3.421) Pub Date : 2023-03-22 ,DOI:10.1016/j.reprotox.2023.108366Kaiqi Chen, Xiaoqian Lu, Dan Xu, Yu Guo, Ying Ao, Hui WangCorn oil, sodium carboxymethyl cellulose (CMC-Na), and dimethyl sulfoxide (DMSO) are widely used as solvents or suspensions in animal experiments, but the effects of prenatal exposure to them on fetal development have not been reported. In this study, Kunming mice were given a conventional dose of corn oil (9.2 g/kg·d), CMC-Na (0.05 g/kg·d) or DMSO (0.088 g/kg·d) during gestation days 10-18, and the ...
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Recent Development of Self-Powered Tactile Sensors Based on Ionic HydrogelsGels Pub Date : 2023-03-22 ,DOI:10.3390/gels9030257Zhen Zhao, Yong-Peng Hu, Kai-Yang Liu, Wei Yu, Guo-Xian Li, Chui-Zhou Meng, Shi-Jie GuoHydrogels are three-dimensional polymer networks with excellent flexibility. In recent years, ionic hydrogels have attracted extensive attention in the development of tactile sensors owing to their unique properties, such as ionic conductivity and mechanical properties. These features enable ionic hydrogel-based tactile sensors with exceptional performance in detecting human body movement and identifying ...
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Tuning an efficient Escherichia coli whole-cell catalyst expressing l-pantolactone dehydrogenase for the biosynthesis of d-(−)-pantolactoneJournal of Biotechnology (IF 3.595) Pub Date : 2023-03-21 ,DOI:10.1016/j.jbiotec.2023.03.004Fang-Ying Zhu, Qing Yang, Min Cao, Ken Zheng, Xiao-Jian Zhang, Qi Shen, Xue Cai, Zhi-Qiang Liu, Yu-Guo Zhengd-(−)-Pantolactone (DPL) is a key intermediate for the production of d-(+)-pantothenate (vitamin B5). Deracemization of d,l-pantolactone (D,L-PL) through oxidizing l-(+)-pantolactone (LPL) to ketopantoyl lactone (KPL) and subsequently reducing KPL to DPL is a promising route for synthesizing DPL. Herein, a newly mined l-pantolactone dehydrogenase from Rhodococcus hoagie (RhoLPLDH) was used for the ...
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Fast and Stable Charge Transfer at Lithium-Sulfide (Electrolyte) Interface via In-Situ Solidified Li+-Conductive InterlayerMaterials Chemistry Frontiers (IF 8.683) Pub Date : 2023-03-21 ,DOI:10.1039/d3qm00049dYa-Hui Wang, Xu-Sheng Zhang, Cai-Cai Li, Hao Zeng, Zhe Chen, Liang Zhang, Jin-Chi Zheng, Yuan Luo, Sen Xin, Yu-Guo GuoWith high Li+ conductivity and mechanical plasticity, sulfide electrolytes such as glassy 75Li2S-25P2S5 (LPS) have become promising solid electrolytes for building rechargeable lithium-metal batteries. However, the sulfide electrolyte usually shows unstable interfacial electrochemistry versus Li metal, which could invite parasitic reactions and dendrite formation and account for rapid performance fade ...
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Hydrogen isotope effects: A new path to high-energy aqueous rechargeable Li/Na-ion batterieseScience Pub Date : 2023-03-21 ,DOI:10.1016/j.esci.2023.100121Xue-Ting Li, Jia Chou, Yu-Hui Zhu, Wen-Peng Wang, Sen Xin, Yu-Guo GuoAqueous rechargeable Li/Na-ion batteries have shown promise for sustainable large-scale energy storage due to their safety, low cost, and environmental benignity. However, practical applications of aqueous batteries are plagued by water’s intrinsically narrow electrochemical stability window, which results in low energy density. In this perspective article, we review several strategies to broaden the ...
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Genomic rearrangements and evolutionary changes in 3D chromatin topologies in the cotton tribe (Gossypieae)BMC Biology (IF 7.364) Pub Date : 2023-03-20 ,DOI:10.1186/s12915-023-01560-yXiaochong Li, Jinbin Wang, Yanan Yu, Guo Li, Jinpeng Wang, Changping Li, Zixian Zeng, Ning Li, Zhibin Zhang, Qianli Dong, Yiyang Yu, Xiaofei Wang, Tianya Wang, Corrinne E. Grover, Bin Wang, Bao Liu, Jonathan F. Wendel, Lei GongAnalysis of the relationship between chromosomal structural variation (synteny breaks) and 3D-chromatin architectural changes among closely related species has the potential to reveal causes and correlates between chromosomal change and chromatin remodeling. Of note, contrary to extensive studies in animal species, the pace and pattern of chromatin architectural changes following the speciation of ...
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Effect of Wax on Cohesive Behavior of Gas Hydrate under High PressureEnergy & Fuels (IF 4.654) Pub Date : 2023-03-16 ,DOI:10.1021/acs.energyfuels.2c04379Shi-Dong Zhou, Zhen-Hao Ren, Yu Guo, Wen-Rui Zhou, Yang LiuIn the deep-sea crude oil pipeline, the formation of hydrates and the deposition of wax will cause pipeline blockage under adverse conditions. Moreover, the interaction of wax and hydrates will lead to a higher tendency of pipeline blockage, which will pose a huge threat to the transportation of crude oil on the sea floor. In order to clarify the effect of wax on cohesive behavior of gas hydrate, the ...
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Improving maritime traffic surveillance in inland waterways using the robust fusion of AIS and visual dataOcean Engineering (IF 4.372) Pub Date : 2023-03-16 ,DOI:10.1016/j.oceaneng.2023.114198Jingxiang Qu, Ryan Wen Liu, Yu Guo, Yuxu Lu, Jianlong Su, Peizheng LiTo guarantee vessel traffic safety in inland waterways, the automatic identification system (AIS) and shore-based cameras have been widely adopted to monitor moving vessels. The AIS data could provide the unique maritime mobile service identity (MMSI), position coordinates (i.e., latitude and longitude), course over ground, and speed over ground for the vessels of interest. In contrast, the cameras ...
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Space-Confined Electrochemical Reactions and Materials for High-Energy-Density BatteriesAccounts of Materials Research Pub Date : 2023-03-16 ,DOI:10.1021/accountsmr.3c00017Juan Zhang, Yi-Fan Tian, Sen Xin, Yu-Guo GuoLithium-ion batteries have demonstrated their profound impacts on global energy transition over the past few decades. Conventional Li-ion batteries operated based on topochemical Li+ intercalation in layered-structure electrode materials usually show highly stable and reversible electrode reactions yet limited energy-storage capability and cannot meet the increasing demands for electric cars and other ...
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Identification of circular RNAs expression pattern in caprine fetal fibroblast cells exposed to a chronic non-cytotoxic dose of graphene oxide-silver nanoparticle nanocompositesFrontiers in Bioengineering and Biotechnology (IF 6.064) Pub Date : 2023-03-16 ,DOI:10.3389/fbioe.2023.1090814Yu-Guo Yuan, Yi-Tian Xing, Song-Zi Liu, Ling Li, Abu Musa Md Talimur Reza, He-Qing Cai, Jia-Lin Wang, Pengfei Wu, Ping Zhong, Il-Keun KongThe widespread use of graphene oxide-silver nanoparticle nanocomposites (GO-AgNPs) in biomedical sciences is increasing the chances of human and animal exposure to its chronic non-toxic doses. Exposure to AgNPs-related nanomaterials may result in the negative effect on the dam, fetus and offspring. However, there are only little available information for profound understanding of the epigenetic alteration ...
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Head-to-head comparison of 6 plasma biomarkers in early multiple system atrophynpj Parkinson's Disease (IF 9.304) Pub Date : 2023-03-15 ,DOI:10.1038/s41531-023-00481-5Yu Guo, Xue-Ning Shen, Shu-Yi Huang, Shu-Fen Chen, Hui-Fu Wang, Wei Zhang, Ya-Ru Zhang, Wei Cheng, Mei Cui, Qiang Dong, Jin-Tai YuThere is a dire need for reliable biomarkers to solidify an early and accurate diagnosis of multiple system atrophy (MSA). We sought to compare the ability of emerging plasma markers in distinguishing MSA from its mimics and healthy controls in early disease stages, and to evaluate their performance in detecting disease severity and brain atrophy. Plasma neurofilament light (NfL), glial fibrillary ...
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AQP4 Aggravates Cognitive Impairment in Sepsis-Associated Encephalopathy through Inhibiting Nav1.6-Mediated Astrocyte AutophagyAdvanced Science (IF 17.521) Pub Date : 2023-03-15 ,DOI:10.1002/advs.202205862Dan-Dan Zhu, Yue-Lin Huang, Song-Yu Guo, Na Li, Xue-Wei Yang, Ao-Ran Sui, Qiong Wu, Yue Zhang, Yue Kong, Qi-Fa Li, Ting Zhang, Wen-Fei Zheng, Ai-Ping Li, Jian Yu, Tong-Hui Ma, Shao LiThe pathology of sepsis-associated encephalopathy (SAE) is related to astrocyte-inflammation associated with aquaporin-4 (AQP4). The aim here is to investigate the effects of AQP4 associated with SAE and reveal its underlying mechanism causing cognitive impairment. The in vivo experimental results reveal that AQP4 in peripheral blood of patients with SAE is up-regulated, also the cortical and hippocampal ...
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Experimental investigation of statistical characteristics of elastic mechanical parameters and strength indexes of rockfill particlesGranular Matter (IF 3.01) Pub Date : 2023-03-14 ,DOI:10.1007/s10035-022-01302-xYu Guo, Shichun Chi, Xiaofei Mi, Shihao YanRockfill is a common irregular granular material used in most dam construction projects. The purpose of this paper is to investigate the distribution and size-dependent properties of the mechanical parameters describing the elastic properties and crushing strength of rockfill particles. These statistics can be used as a reference to calibrate the input parameters of numerical models when studying the ...
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Fixed time robust control for tower cranes with unmatched disturbances and input saturationInternational Journal of Adaptive Control and Signal Processing (IF 3.369) Pub Date : 2023-03-14 ,DOI:10.1002/acs.3574Xiutao Gu, Yuanqi Li, Mengqing Hong, Song Ye, Yu GuoTo address the challenging problem of fixed-time anti-sway and positioning control for tower cranes with uncertain disturbances and input saturation, a novel fixed-time anti-saturation robust algorithm is proposed. First, on the basis of a newly designed fixed-time convergence system, a fixed-time disturbance observer (FTDO) is developed to estimate the matched and unmatched disturbances. Then, an ...
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Ring-Opening Polymerization of a Seven-Membered Lactone toward a Biocompatible, Degradable, and Recyclable Semi-aromatic PolyesterMacromolecules (IF 6.057) Pub Date : 2023-03-14 ,DOI:10.1021/acs.macromol.2c02172Mao-Qin Li, Zi-Xuan Luo, Xiao-Yan Yu, Guo-Qiang Tian, Gang Wu, Si-Chong Chen, Yu-Zhong WangThe widespread use of polymer materials and their improper disposal have resulted in significant environmental pollution and wastage of resources. Therefore, the design of chemically recyclable, environmentally compatible, and applicable polymers represents a new approach for a green and circular polymer economy, and it has become a major focus worldwide. Herein, we efficiently synthesized a seven-membered ...
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Assessment of integrated patterns of human-animal-environment health: a holistic and stratified analysisInfectious Diseases of Poverty (IF 10.485) Pub Date : 2023-03-14 ,DOI:10.1186/s40249-023-01069-0Zhao-Yu Guo, Jia-Xin Feng, Lin Ai, Jing-Bo Xue, Jing-Shu Liu, Xiao-Xi Zhang, Chun-Li Cao, Jing Xu, Shang Xia, Xiao-Nong Zhou, Jin Chen, Shi-Zhu Li
Data-driven research is a very important component of One Health. As the core part of the global One Health index (GOHI), the global One Health Intrinsic Drivers index (IDI) is a framework for evaluating the baseline conditions of human-animal-environment health. This study aims to assess the global performance in terms of GOH-IDI, compare it across different World Bank regions, and analyze the relationships
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Sophisticated Prediction of Carotid-Plaque Vulnerability by Nanocluster Sensitized Vessel-Wall-Imaging Profile in RabbitmedRxiv - Radiology and Imaging Pub Date : 2023-03-13 ,DOI:10.1101/2023.03.09.23287077Yan Gong, Menglin Wu, Dingwei Fu, Yu Guo, Xiudi Lu, Ying Zou, Xiang Zhang, Jinxia Zhu, Xianchang Zhang, Xue Li, Shuang Xia
OBJECTIVE: To innovatively developed a macrophage-target nanoparticle based contrast-enhanced high-resolution magnetic resonance vessel wall imaging (HR-VWI) strategy to characterize the plaques vulnerable features on rabbits. BACKGROUND: Lacking of sensitive and specific image-marker of HR-VWI leads this technique depending upon the plaque morphological characteristics. Nanoparticle-based contrast
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Helicobacter pylori multiplex serology and risk of non-cardia and cardia gastric cancer: a case-cohort study and meta-analysisInternational Journal of Epidemiology (IF 9.685) Pub Date : 2023-03-13 ,DOI:10.1093/ije/dyad007Pang Yao, Christiana Kartsonaki, Julia Butt, Rima Jeske, Catherine de Martel, Martyn Plummer, Yu Guo, Sarah Clark, Robin G Walters, Yiping Chen, Daniel Avery, Jun Lv, Canqing Yu, Hao Wang, Michael Hill, Richard Peto, Liming Li, Tim Waterboer, Zhengming Chen, Iona Y Millwood, Ling Yang
Background Helicobacter pylori infection is a major cause of non-cardia gastric cancer (NCGC), but uncertainty remains about the associations between sero-positivity to different H. pylori antigens and risk of NCGC and cardia gastric cancer (CGC) in different populations. Methods A case-cohort study in China included ∼500 each of incident NCGC and CGC cases and ∼2000 subcohort participants. Sero-positivity
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Preparation and electrothermal performance of onion-like carbon/carbon nanofibre composite filmChemical Physics Letters (IF 2.719) Pub Date : 2023-03-11 ,DOI:10.1016/j.cplett.2023.140429Ze-yu Guo, He-Dong Huang, Ding Nan, Yong-Fei Ren, Fan-jie Meng, Xin-yue Liang, Hao Pu, Hai-yang Jia, Zhong-ran Zhou, Peng Chen, Jie WuAn onion-like carbon/carbon nanofibre composite film was prepared by electrospinning. Its precursor application, and the effect of the amount of onion-like carbon additive and carbonization temperature on the physical and chemical properties of onion-like carbon/carbon nanofibre composite film was investigated. The results showed the non-woven fabric obtained by electrospinning solution reagent and ...
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A pilot study on lengthening potentials and biomechanical effects of double and triple hemisection on tendon with slide lengtheningScientific Reports (IF 4.996) Pub Date : 2023-03-09 ,DOI:10.1038/s41598-023-30791-wT. Wang, H. Yu, Guo-fu Tian, Rui-xiang Zhao
The current study explored the slide-lengthening potentials of double and triple hemisections and the biomechanical effects of different inter-hemisection distances. Forty-eight porcine flexor digitorum profundus tendons were divided into double- and triple-hemisection groups (Groups A and B) and a control group (Group C). Group A was divided into Group A1 (distance between hemisections were the same
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Polarization-diverse soliton transitions and deterministic switching dynamics in strongly-coupled and self-stabilized microresonator frequency combsarXiv - PHYS - Optics Pub Date : 2023-03-07 ,DOI:arxiv-2303.03687Wenting Wang, Heng Zhou, Xinghe Jiang, Tristan Melton, Abhinav Kumar Vinod, Mingbin Yu, Guo-Qiang Lo, Dim-Lee Kwong, Chee Wei WongDissipative Kerr soliton microcombs in microresonators has enabled fundamental advances in chip scale precision metrology, communication, spectroscopy, and parallel signal processing. Here we demonstrate polarization diverse soliton transitions and deterministic switching dynamics of a self stabilized microcomb in a strongly coupled dispersion-managed microresonator driven with a single pump laser ...
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Polarization-diverse soliton transitions and deterministic switching dynamics in strongly-coupled and self-stabilized microresonator frequency combsarXiv - PHYS - Applied Physics Pub Date : 2023-03-07 ,DOI:arxiv-2303.03687Wenting Wang, Heng Zhou, Xinghe Jiang, Tristan Melton, Abhinav Kumar Vinod, Mingbin Yu, Guo-Qiang Lo, Dim-Lee Kwong, Chee Wei WongDissipative Kerr soliton microcombs in microresonators has enabled fundamental advances in chip scale precision metrology, communication, spectroscopy, and parallel signal processing. Here we demonstrate polarization diverse soliton transitions and deterministic switching dynamics of a self stabilized microcomb in a strongly coupled dispersion-managed microresonator driven with a single pump laser ...
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Integration of multi-omics data reveals a novel hybrid breast cancer subtype and its biomarkersFrontiers in Oncology (IF 5.738) Pub Date : 2023-03-06 ,DOI:10.3389/fonc.2023.1130092Zhen-zhen Wang, Xu-hua Li, Xiao-ling Wen, Na Wang, Yu Guo, Xu Zhu, Shu-heng Fu, Fei-fan Xiong, Jing Bai, Xiao-ling Gao, Hong-jiu WangTumor heterogeneity in breast cancer hinders proper diagnosis and treatment, and the identification of molecular subtypes may help enhance the understanding of its heterogeneity. Therefore, we proposed a novel integrated multi-omics approach for breast cancer typing, which led to the identification of a hybrid subtype (Mix_Sub subtype) with a poor survival prognosis. This subtype is characterized by ...
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The effect of position of (-)-menthyl on the mesomorphic and photoisomerization behavior in azobenzene chiral liquid crystalsJournal of Molecular Structure (IF 3.841) Pub Date : 2023-03-03 ,DOI:10.1016/j.molstruc.2023.135282Tuan-Yu Guo, Zhang-Pei Chen, Jiao-Fen Lin, Zhen-Zhen Cai, Hong-Lu Xie, Aikebaier Reheman, Ying-Gang JiaAs the mesomorphic type of liquid crystals could be largely altered by the molecular chirality, we herein explored the effect of position of chiral (-)-menthyl on the mesomorphic and photoisomerization behavior in azobenzene liquid crystals. By modifying the position of chiral (-)-menthyl in the menthol based liquid crystal compounds through gradually increasing the alkyl chain length of the dicarboxylic ...
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Genome-wide survival study identifies PARL as a novel locus for clinical progression and neurodegeneration in Alzheimer’s diseaseBiological Psychiatry (IF 12.81) Pub Date : 2023-03-03 ,DOI:10.1016/j.biopsych.2023.02.992Shi-Dong Chen, Wei Zhang, Yi-Wei Feng, Bang-Sheng Wu, Liu Yang, Ya-Ru Zhang, Hui-Fu Wang, Yu Guo, Yue-Ting Deng, Jian-Feng Feng, Wei Cheng, Qiang Dong, Jin-Tai YuBackground Variability exists in trajectories of Alzheimer’s disease (AD). We aimed to identify genetic modulators of clinical progression in AD. Methods We conducted the first genome-wide survival study on AD using a two-stage approach. The discovery and replication stage separately included 1,158 and 211,817 non-demented individuals from Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the ...
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Efficacy and safety of Tuina for chronic nonspecific low back pain: A PRISMA-compliant systematic review and meta-analysis.Medicine (IF 1.817) Pub Date : 2023-3-3 ,DOI:10.1097/md.0000000000033018Juan Yang, Xuan Zhou, Qingyu Ma, Jeffrey T Woods, Arya B Mohabbat, Alexander Do, Jeffrey S Brault, Mark A Jensen, Kyung-Min Shin, Longbin Shen, Canghuan Zhao, Kwok Chee Philip Cheong, Kejie He, Yu Guo, Zhuoming Chen, Shujie Tang, Yong Tang, Celia Ia Choo Tan, Jiaxu Chen, Brent A Bauer
Chronic nonspecific low back pain (CNLBP) is a serious medical and social problem resulting in functional decline and decreased work ability. Tuina, a form of manual therapy, has been sparsely used to treat patients with CNLBP. To systematically assess the efficacy and safety of Tuina for patients with CNLBP.
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Endovascular treatment achieves better outcomes than best medical management in patients with M2 occlusion and high stroke severity: a meta-analysisJournal of Neurology (IF 6.682) Pub Date : 2023-03-02 ,DOI:10.1007/s00415-023-11653-xYu Guo, Hao Wu, Tian-yi Zhang, Yu-ping Li, Jin-cai Yang, Ming-fei Yang, Yi-qiao Hu, Heng-zhu ZhangBackground The lack of randomized evidence makes it difficult to establish reliable treatment recommendations for patients with M2 occlusion. This study aims to compare the efficacy and safety of endovascular treatment (EVT) with best medical management (BMM) in patients with M2 occlusion, and to investigate whether the optimal treatment varies according to stroke severity. Methods Comprehensive literature ...
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Preservation status and microbial community of waterlogged archaeological woods over 7800 years old at the Jingtoushan Site, ChinaWood Science and Technology (IF 2.898) Pub Date : 2023-03-02 ,DOI:10.1007/s00226-023-01463-9Yang Lu, Lichao Jiao, Guoping Sun, Jie Wang, Shoujia Liu, Ren Li, Yonggang Zhang, Yu Guo, Juan Guo, Xiaomei Jiang, Yafang YinThe Jingtoushan Site (8300–7800 BP), located in Ningbo City, Zhejiang Province, is of great value for the in-depth understanding of China’s prehistoric coastal culture. At this site, numerous valuable wooden relics showing past human civilization have been discovered. Multiple approaches were taken, including wood anatomy and physicochemical analyses, to assess the preservation state of waterlogged ...
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