- 作 者: "fen du"
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Insight into the Compositional Features of Organic Matter in Xilinguole Lignite through Two Mass SpectrometersACS Omega (IF 4.132) Pub Date : 2022-12-05 ,DOI:10.1021/acsomega.2c05051Sheng Li, Fen-Fen Du, Zhi-Hao Ma, Li-Hong Zhang, Zhong-Qiu Liu, Tian-Sheng Zhao, Xian-Yong Wei, Mei-Ling Xu, Xing-shun CongEthanolysis of lignite is an effective approach for converting organic matter of lignite to liquid coal derivatives. Xilinguole lignite (XL) was reacted with ethanol at 320 °C. Then ethanol and isometric carbon disulfide/acetone mixture were used to extract the reaction mixture in a modified Soxhlet extractor to afford extractable portion 1 (EP1) and extractable portion 2 (EP2), respectively. According ...
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Interfacial Mechanical Behavior in Nacre of Red Abalone and Other Shells: A ReviewACS Biomaterials Science & Engineering (IF 5.395) Pub Date : 2022-08-12 ,DOI:10.1021/acsbiomaterials.2c00080Fen Du, Saleh Alghamdi, Jie Yang, Dryver Huston, Ting TanInterfaces between nacreous tablets are crucial to the outstanding mechanical properties of nacre in natural shells. Excellent research has been conducted to probe the effect of interfaces on strength and toughness of nacre, providing critical guidelines for the design of human-made laminated composites. This article reviews recent studies on interfacial mechanical behavior of nacre in red abalone ...
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A Preliminary Study on the Flexural Behavior of Nacre-Inspired Cementitious MaterialsJOM (IF 2.597) Pub Date : 2022-07-07 ,DOI:10.1007/s11837-022-05348-3Meshari Alsharif, Fen Du, Sami Althobaiti, Mohammed Alahmari, Hashem Alattas, Abdulrahman Aljahani, Ting Tan, Saleh AlghamdiThere exist numerous instances of natural materials with hierarchical and layered microstructures having superior mechanical and functional properties. An example of such a material is nacre, which is a tough natural composite found in the inner part of many seashells. This preliminary study aimed to obtain an understanding of the flexural strength and ductility of bio-inspired cementitious samples ...
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Three-Dimensional Trapping and Manipulation of a Mie Particle by Hybrid Acoustic Focused Petal BeamsPhysical Review Applied (IF 4.931) Pub Date : 2022-06-29 ,DOI:10.1103/physrevapplied.17.064059Yan-Chun Luo, Xin-Rui Li, Da-Jian Wu, Jie Yao, Xing-Feng Zhu, Liang-Fen Du, Xiao-Jun LiuAcoustic manipulations of microparticles have significant implications in physics, chemistry, biology, and biomedicine. For large Mie particles, both the scattering force and the gradient force affect the trapping and manipulation behaviors, and thus, a passive acoustic tweezer (AT) for three-dimensionally manipulating a Mie particle remains challenging. Here, a passive AT based on a hybrid acoustic ...
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Appropriate Soil Heat Treatment Promotes Growth and Disease Suppression of Panax notoginseng by Interfering with the Bacterial Community.Journal of Microbiology and Biotechnology (IF 3.277) Pub Date : 2022-02-17 ,DOI:10.4014/jmb.2112.12005Ying-Bin Li, Zhi-Ping Zhang, Ye Yuan, Hui-Chuan Huang, Xin-Yue Mei, Fen Du, Min Yang, Yi-Xiang Liu, Shu-Sheng ZhuIn our greenhouse experiment, soil heat treatment groups (50, 80, and 121°C) significantly promote growth and disease suppression of Panax notoginseng in consecutively cultivated soil (CCS) samples (p < 0.01), and 80°C is better than those at 50°C and 121°C (p < 0.01). Furthermore, we found that heat treatment at 80°C changes the microbial diversity in CCS, and the inhibition ratios of culturable microorganisms ...
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Flexural Behavior of Layered PVA Fiber/Steel Fiber Reinforced Cementitious Composite PlatesKSCE Journal of Civil Engineering (IF 2.115) Pub Date : 2021-12-17 ,DOI:10.1007/s12205-021-0350-0Guo, Aofei, Zhou, Fen, Du, Yunxing, Li, ChuntaoPolyvinyl alcohol (PVA) fiber reinforced cementitious composites (PFRCC) and steel fiber reinforced cementitious composites (SFRCC) were combined to develop two-layer cementitious composites (PF/SFRCC) with extraordinary strength and strain capacity. The flexural behavior of the PF/SFRCC plates was studied through the flexural test. The effects of the thickness of PFRCC and the loading face on the ...
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Optimizing inhalation therapy in the aspect of peak inhalation flow rate in patients with chronic obstructive pulmonary disease or asthmaBMC Pulmonary Medicine (IF 3.32) Pub Date : 2021-09-24 ,DOI:10.1186/s12890-021-01674-5Hua, Jian-lan, Ye, Xiao-fen, Du, Chun-ling, Xie, Ning, Zhang, Jie-qing, Li, Man, Zhang, JingPressurized metered dose inhalers (pMDIs) and dry powder inhalers (DPIs) are commonly used drug-delivering devices for patients with chronic airway diseases. Appropriate peak inhalation flow rate (PIFR) and inhaler technique is essential for effective therapy. We aimed at optimizing inhalation therapy through the analysis of PIFRs in patients with chronic obstructive pulmonary disease (COPD) or asthma ...
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Influence of the Preparation Conditions on the Reaction Performance on Steam Reforming of Methanol in a Cu/Zn/Al model catalystChemRxiv Pub Date : 2021-08-31 ,DOI:10.33774/chemrxiv-2021-tjgfbZhao-shun, Zhang, Meng-qian, Li, Sen, Yao, Xing-yu, Li, Fen-fen, Du, Hao-ran, Shi, Xu-bin, Guan
The model Cu/Zn/Al catalysts with different calcination temperature were prepared by hydrothermal method. The catalysts were characterized by XRD, BET, SEM, CO2-TPD, H2-TPR, TG, CH3OH-TPD and CO2+H2-TPSR. The effect of different calcination temperature on structure, stability and catalytic performance for methanol steam reforming at the conditions of 200-320℃ was also represented. The results of present
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Hepatic lysosomal acid lipase drives the autophagy-lysosomal response and alleviates cholesterol metabolic disorder in ApoE deficient miceBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (IF 5.228) Pub Date : 2021-08-17 ,DOI:10.1016/j.bbalip.2021.159027Feifei Li, Xiaojie Zhao, Hao Li, Yu Liu, Yu Zhang, Xiaopeng Huang, Jia Cao, Fen Du, Dongfang Wu, Hong YuLysosomal acid lipase (LAL)-dependent lipolysis degrades cholesteryl ester (CE) and triglyceride in the lysosome. LAL deficiency in human and mice leads to hypercholesterolemia, hepatic CE deposition, and atherosclerosis. Despite its hepatocyte-specific deficiency leads to CE accumulation, the regulation of LAL in cholesterol metabolic disease remains elusive. For the in vitro study, the target gene ...
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VEGF-mediated angiogenesis in retinopathy of prematurity is co-regulated by miR-17-5p and miR-20a-5p.Biochemistry and Cell Biology (IF 3.73) Pub Date : 2021-07-28 ,DOI:10.1139/bcb-2020-0357Yan Guo,Fen Du,Yi-Lan Tan,Jun Luo,Dan Xiong,Wei-Tao SongThe microRNAs miR-17-5p and miR-20a-5p play important roles on angiogenesis; however, it is arguable whether they regulate the formation of retinal blood vessels in retinopathy of prematurity (ROP). We used a mouse model of oxygen-induced retinopathy (OIR) to simulate the development of retinas in mice suffering from ROP, and the expression levels of miR-20a-5p, miR-17-5p, hypoxia-inducible factor ...
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Dynamic Compressive Behavior of CTRC and ECC Layered Concrete under Impact LoadKSCE Journal of Civil Engineering (IF 2.115) Pub Date : 2021-07-21 ,DOI:10.1007/s12205-021-0188-5Guo, Aofei, Zhou, Fen, Du, Yunxing, Yan, RuiIn this study, carbon textile reinforced concrete (CTRC) and engineered cementitious composites (ECC), together with steel fibers, were combined to fabricate two-layer concrete, called CTRC-ECC concrete. The dynamic compressive behavior of CTRC-ECC concrete was studied through the quasi-static compressive test and the impact test using a split Hopkinson pressure bar (SHPB). The effects of the thickness ...
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Hepatic paraoxonase 1 ameliorates dysfunctional high-density lipoprotein and atherosclerosis in scavenger receptor class B type I deficient mice.Annals of Translational Medicine Pub Date : 2021-07-01 ,DOI:10.21037/atm-21-682Xiao-Jie Zhao,Liang-Chen Liu,Cui Guo,Wen-Wen Shen,Jia Cao,Fen Du,Dong-Fang Wu,Hong Yu
BACKGROUND High-density lipoprotein (HDL) plays an antiatherogenic role by mediating reverse cholesterol transport (RCT), antioxidation, anti-inflammation, and endothelial cell protection. Recently, series of evidence have shown that HDL can also convert to proatherogenic HDL under certain circumstances. Plasma paraoxonase 1 (PON1) as an HDL-bound esterase, is responsible for most of the antioxidant
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Recent Studies in Mechanical Properties of Selected Hard-Shelled Seeds: A ReviewJOM (IF 2.597) Pub Date : 2021-04-19 ,DOI:10.1007/s11837-021-04688-wFen Du, Ting TanSeeds and nuts not only serve as important food sources for human beings but also exhibit excellent mechanical properties resulting from their extraordinary shell structures. A literature review has been performed on selected hard-shelled seeds, including almond, brazil nut, chestnut, hazelnut, macadamia, pecan, pistachio, and walnut, for their geometrical, mechanical, and microstructural properties ...
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An N-heterocyclic carbene-catalyzed switchable reaction of 9-(trimethylsilyl)fluorene and aldehydes: chemoselective synthesis of dibenzofulvenes and fluorenyl alcoholsOrganic & Biomolecular Chemistry (IF 3.89) Pub Date : 2021-3-24 ,DOI:10.1039/d1ob00065aYu-Chuan Ma, Jin-Yun Luo, Shi-Chu Zhang, Shu-Hui Lu, Guang-Fen Du, Lin HeAn N-heterocyclic carbene-catalyzed synthesis of dibenzofulvenes and fluorenyl alcohols was developed. In the presence of 10 mol% NHC (1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) and 4 Å molecular sieves, 9-(trimethylsilyl)fluorene undergoes an olefination reaction with aldehydes to produce dibenzofulvenes in 43–99% yields. However, on reducing the NHC loading to 1 mol% and with the addition ...
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Organocatalytic aminocarbonylation of α,β-unsaturated ketones with N,N-dimethyl carbamoylsilaneNew Journal of Chemistry (IF 3.925) Pub Date : 2021-3-19 ,DOI:10.1039/d1nj00782cShou-Shan Yang, Ying-Zheng Ren, Yu-Yu Guo, Guang-Fen Du, Zhi-Hua Cai, Lin HeAn organic superbase-catalyzed aminocarbonylation reaction of α,β-unsaturated ketones was reported. Under the catalysis of 10 mol% Schwesinger's superbase t-Bu-P4, a variety of enones and ynones reacted with N,N-dimethyl carbamoylsilane to afford α-siloxyamides or α-hydroxyamides in 56–82% yields. ...
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Identification of potential serum biomarkers for simultaneously classifying lung adenocarcinoma, squamous cell carcinoma and small cell carcinomaCancer Biomarkers (IF 3.828) Pub Date : 2020-12-18 ,DOI:10.3233/cbm-201440Jiangqing Yu, Fen Du, Liping Yang, Ling Chen, Yuanxiang He, Ruijin Geng, Le Wu, Baogang XieBACKGROUND: Histological subtypes of lung cancer are crucial for making treatment decisions. However, multi-subtype classifications including adenocarcinoma (AC), squamous cell carcinoma (SqCC) and small cell carcinoma (SCLC) were rare in the previous studies. This study aimed at identifying and screening potential serum biomarkers for the simultaneous classification of AC, SqCC and SCLC. PATIENTS ...
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Measurement of stress-time avalanches inside polypropylene fiber reinforced concrete beams during flexureConstruction and Building Materials (IF 7.693) Pub Date : 2020-11-06 ,DOI:10.1016/j.conbuildmat.2020.121428Zhuang Liu, Robert Worley, Fen Du, Dryver Huston, Mandar Dewoolkar, Ting TanIn this work, we studied stress variations of loading histories on polypropylene fiber reinforced concrete beams during flexure. A new experimental system was created to collect the stress-time curves at 100 kHz sampling rate to reveal temporal profiles of stress drops in high resolution. Concrete beams prepared at the early age of seven days with different fiber volume fractions were loaded at various ...
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A study on avalanches of early age basalt fiber reinforced concrete beams during flexureJournal of Cleaner Production (IF 11.072) Pub Date : 2020-08-15 ,DOI:10.1016/j.jclepro.2020.123695Zhuang Liu, Robert Worley, Fen Du, Courtney D. Giles, Mandar Dewoolkar, Dryver Huston, Ting TanIn this work, stress variations during flexure of early age basalt fiber reinforced concrete beams were studied using high resolution temporal measurements. An experimental system was created to collect stress-time curves at 100 kHz sampling rate so that temporal profiles of stress variations were analyzed in detail. Stress drops were modeled as avalanches resulting from interactions between basalt ...
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Avalanches during flexure of early-age steel fiber reinforced concrete beamsMaterials and Structures (IF 4.285) Pub Date : 2020-06-29 ,DOI:10.1617/s11527-020-01520-wZhuang Liu, Robert Worley, Fen Du, Courtney D. Giles, Mandar Dewoolkar, Dryver Huston, Ting TanIn this work, we studied stress variations occurring during flexure of early-age steel fiber reinforced concrete beams. By preparing beams with different fiber volume ratios, four-point bending tests were performed to evaluate the specimens at different loading rates. A new experimental system was created to collect the stress-time curves collected at 100 kHz sampling rate so that temporal profiles ...
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Sliding Avalanches Between Nacreous Tablets.Nano Letters (IF 12.262) Pub Date : 2020-06-08 ,DOI:10.1021/acs.nanolett.0c01148Saleh Alghamdi,Zhuang Liu,Fen Du,Jie Yang,Karin A Dahmen,Ting TanNacre, also known as mother of pearl, possesses extraordinary mechanical properties resulting from its intriguing hierarchical brick-and-mortar microstructures. Despite prior studies, interactions between nanoasperities during sliding still need to be elucidated. In this study, we measure slip events between nanograins of microlayers at high temporal resolution during torsion-induced sliding. We model ...
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Tensile and shear behavior of microscale growth layers between nacre in red abaloneJournal of the Mechanics and Physics of Solids (IF 5.582) Pub Date : 2020-02-29 ,DOI:10.1016/j.jmps.2020.103928Saleh Alghamdi, Fen Du, Jie Yang, George Pinder, Ting TanThe microscale growth layers between nacre possess distinctive aragonite structures, including columns, spherulites and organic matrices. High temporal resolution experiments were performed to elucidate the tensile and shear behavior of growth layers under dry and hydrated conditions. For a comparison, pure nacre was tested in corresponding conditions. For both nacre and growth layers, the presence ...
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FGFR1 Induces Acquired Resistance Against Gefitinib By Activating AKT/mTOR Pathway In NSCLC.OncoTargets and Therapy (IF 4.345) Pub Date : 2019-11-18 ,DOI:10.2147/ott.s220462Dan Zhang,Li-Li Han,Fen Du,Xiao-Meng Liu,Jin Li,Hui-Hui Wang,Ming-Hui Song,Zeng Li,Guo-Yin Li
OBJECTIVE As an epidermal growth factor, receptor-tyrosine kinase inhibitor (EGFR-TKI), gefitinib demonstrates a good therapeutic effect in patients with EGFR-mutant non-small-cell lung cancer (NSCLC). However, an overwhelming majority of these patients inevitably develop resistance against gefitinib. Unfortunately, the mechanism underlying this phenomenon is still not fully understood. Here we aim
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[Effects of combined red, blue and white LED light on the quality of eggplant seedlings and fruit peels.]Ying yong sheng tai xue bao = The journal of applied ecology Pub Date : 2019-09-19 ,DOI:10.13287/j.1001-9332.201909.027Yu Fen DU,Zhi Gao,Qing Hua DI,Feng Juan Yang,Xiu Feng Wang,Min Wei,Qing Hua Mi,Yan LiThe effects of red/blue=3/1 [R/B=3/1(9/3), as control, CK1], white light (W, as control, CK2), and combined light of red, blue and white [R/B/W=3/1/1 (9/3/3), T1; R/B/W=9/3/8, T2; R/B/W=3/1/6 (9/3/18), T3; R/B/W=3/1/16 (9/3/48), T4] on the growth, root development, quality and yield of eggplants were examined to provide theoretical and technical support for intensive and high-efficient light supplement ...
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An experimental study on the fracture of a unidirectional carbon fiber-reinforced composite under quasistatic torsionComposites Part B: Engineering (IF 11.322) Pub Date : 2019-09-01 ,DOI:10.1016/j.compositesb.2019.05.080Fen Du,Saleh Alghamdi,Brian Riabbans,Ting TanAbstract Carbon fiber-reinforced composites exhibit excellent mechanical properties for a variety of applications. Using the spirally notched specimens, we demonstrate how unidirectional carbon fiber-reinforced polymeric composite specimens with different fiber orientations fail under quasistatic torsion. By collecting data at 200,000 points per second, type I specimens exhibited limited fluctuations ...
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Compressive deformation and failure of trabecular structures in a turtle shell.Acta Biomaterialia (IF 10.633) Pub Date : 2019-07-13 ,DOI:10.1016/j.actbio.2019.07.023Edward Ampaw,Tunji Adetayo Owoseni,Fen Du,Nelson Pinilla,John Obayemi,Jingjie Hu,Pierre-Marie Nigay,Ange Nzihou,Vanessa Uzonwanne,Martiale Gaetan Zebaze-Kana,Mandar Dewoolkar,Ting Tan,Winston SoboyejoTurtle shells comprising of cortical and trabecular bones exhibit intriguing mechanical properties. In this work, compression tests were performed using specimens made from the carapace of Kinixys erosa turtle. A combination of imaging techniques and mechanical testing were employed to examine the responses of hierarchical microstructures of turtle shell under compression. Finite element models produced ...
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Stereoselective synthesis of α-fluoroacrylonitriles via organocatalytic cyanation of gem-difluoroalkenes and TMSCN†New Journal of Chemistry (IF 3.925) Pub Date : 2019-06-19 ,DOI:10.1039/c9nj02370dYu-Chuan Ma,Yang Zhang,Cheng-Zhi Gu,Guang-Fen Du,Lin HeAn organocatalytic cyanation reaction of gem-difluoroalkenes was developed. Under the catalysis of 10 mol% DBU, gem-difluoroalkenes undergo a nucleophilic addition-β-elimination reaction with trimethylsilyl cyanide to provide α-fluoroacrylonitriles in 50–98% yields with excellent Z/E selectivity. ...
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Modeling and thermodynamic cycle analysis of condensation-induced depressurizationVacuum (IF 4.11) Pub Date : 2019-06-01 ,DOI:10.1016/j.vacuum.2019.02.052Bo Zhang, Fen Du, Guangyu Guo, Chao Zhu, Zhiming Ji, Chao-Hsin LinAbstract A condensation-induced depressurization and steam purging technology has been recently developed to drive a continuous gas flow at a sub-atmospheric pressure. The technology is based on a continuous regeneration of depressurization by a system of two or multiple alternatively-operated chambers with steam condensation and refilling. Comparing with traditional methods, this new vacuum generation ...
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N-Heterocyclic carbene-catalyzed diastereoselective synthesis of sulfenylated indanes via sulfa-Michael–Michael (aldol) cascade reactionsOrganic & Biomolecular Chemistry (IF 3.89) Pub Date : 2019-04-12 ,DOI:10.1039/c9ob00210cZe-Nan Feng,Jin-Yun Luo,Yang Zhang,Guang-Fen Du,Lin HeN-Heterocyclic carbene (NHC)-catalyzed diastereoselective synthesis of multisubstituted sulfenylated indanes has been developed. In the presence of 1 mol% NHC, various thiols underwent the sulfa-Michael–Michael cascade reaction with benzenedi(enones) efficiently to form the carbon–sulfur bond and construct sulfenylated indanes in good to excellent yields with high diastereoselectivity. In addition ...
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Expression profile of microRNAs in porcine alveolar macrophages after Toxoplasma gondii infection.Parasites & Vectors (IF 4.047) Pub Date : 2019-01-31 ,DOI:10.1186/s13071-019-3297-ySenyang Li,Jing Yang,Luyao Wang,Fen Du,Junlong Zhao,Rui Fang
BACKGROUND Toxoplasma gondii is an apicomplexan protozoan parasite that can cause serious clinical illnesses in both humans and animals. microRNAs (miRNAs) are non-protein-coding RNAs that can regulate the expression of target genes. A previous study found that many miRNAs were differentially expressed after T. gondii infection and exert significant effects and revealed that both host survival and
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Cost-effectiveness of Teriflunomide Compared to Interferon Beta-1b for Relapsing Multiple Sclerosis Patients in China.Clinical Drug Investigation (IF 3.58) Pub Date : 2019-01-27 ,DOI:10.1007/s40261-019-00750-3Yan Xu,Ningying Mao,Viktor Chirikov,Fen Du,Yu-Chen Yeh,Li Liu,Ruiqi Liu,Xin Gao
BACKGROUND AND OBJECTIVE Teriflunomide is a once-daily oral immunomodulatory agent approved in 80 countries for the treatment of patients with relapsing multiple sclerosis (RMS). The study objective was to estimate the cost effectiveness of teriflunomide (14 mg tablet, daily) versus interferon beta-1b (250 mcg subcutaneous injection, every other day) among RMS patients from the Chinese healthcare system
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