- 作 者: ( "dongcheng wu" OR "dong-cheng wu" )
-
Intravoxel incoherent motion imaging combined with diffusion kurtosis imaging to assess the response to radiotherapy in a rabbit VX2 malignant bone tumor modelCancer Imaging (IF 5.605) Pub Date : 2022-09-05 ,DOI:10.1186/s40644-022-00488-wGuo, Jia, Sun, Weikai, Dong, Cheng, Wu, Zengjie, Li, Xiaoli, Zhou, Ruizhi, Xu, Wenjian
To combine intravoxel incoherent motion (IVIM) imaging and diffusion kurtosis imaging (DKI) parameters for the evaluation of radiotherapy response in rabbit VX2 malignant bone tumor model. Forty-seven rabbits with bone tumor were prospectively enrolled and divided into pre-treatment, considerable effect and slight effect group. Treatment response was evaluated using IVIM-DKI. IVIM-based parameters
...
-
Human umbilical cord mesenchymal stem cells ameliorate acute liver failure by inhibiting apoptosis, inflammation and pyroptosis.Annals of Translational Medicine Pub Date : 2021-11-01 ,DOI:10.21037/atm-21-2885Mengting Liu,Jing He,Shuo Zheng,Ke Zhang,Yu Ouyang,Yaqi Zhang,Changyong Li,Dongcheng Wu
BACKGROUND Human umbilical cord mesenchymal stem cells (UC-MSCs) are multipotent progenitor cells representing an attractive therapeutic tool for tissue damage and inflammation owing to their unique immunomodulatory properties. This study was designed to determine the protective effects and underlying mechanisms of UC-MSCs on acute liver failure (ALF). METHODS ALF was induced in mice by intraperitoneal
...
-
Intra-articular injection of human umbilical cord mesenchymal stem cells ameliorates monosodium iodoacetate-induced osteoarthritis in rats by inhibiting cartilage degradation and inflammation.Bone & Joint Research (IF 4.41) Pub Date : 2021-3-20 ,DOI:10.1302/2046-3758.103.bjr-2020-0206.r2Quan Zhang, E Xiang, Wei Rao, Ya Qi Zhang, Cui Hong Xiao, Chang Yong Li, Bing Han, Dongcheng Wu
This study aimed to investigate whether human umbilical cord mesenchymal stem cells (UC-MSCs) can prevent articular cartilage degradation and explore the underlying mechanisms in a rat osteoarthritis (OA) model induced by monosodium iodoacetate (MIA).
...
-
Human Umbilical Cord Mesenchymal Stem Cells Improve Ovarian Function in Chemotherapy-Induced Premature Ovarian Failure Mice Through Inhibiting Apoptosis and Inflammation via a Paracrine MechanismReproductive Sciences (IF 2.924) Pub Date : 2021-03-09 ,DOI:10.1007/s43032-021-00499-1Taoran Deng, Jing He, Qingyun Yao, Linjing Wu, Liru Xue, Mingfu Wu, Dongcheng Wu, Changyong Li, Yufeng LiHuman umbilical cord mesenchymal stem cell (UC-MSC) application is a promising arising therapy for the treatment of premature ovarian failure (POF). However, little is known about the inflammation regulatory effects of human umbilical cord MSCs (UC-MSCs) on chemotherapy-induced ovarian damage, regardless of in vivo or in vitro. This study was designed to investigate the therapeutic effects of UC-MSC ...
-
Human Umbilical Cord Mesenchymal Stem Cells Improve Ovarian Function in Chemotherapy-Induced Premature Ovarian Failure Mice Through Inhibiting Apoptosis and Inflammation via a Paracrine Mechanism.Reproductive Sciences (IF 2.924) Pub Date : 2021-03-09 ,DOI:10.1007/s43032-021-00499-1Taoran Deng,Jing He,Qingyun Yao,Linjing Wu,Liru Xue,Mingfu Wu,Dongcheng Wu,Changyong Li,Yufeng LiHuman umbilical cord mesenchymal stem cell (UC-MSC) application is a promising arising therapy for the treatment of premature ovarian failure (POF). However, little is known about the inflammation regulatory effects of human umbilical cord MSCs (UC-MSCs) on chemotherapy-induced ovarian damage, regardless of in vivo or in vitro. This study was designed to investigate the therapeutic effects of UC-MSC ...
-
Human Umbilical Cord Mesenchymal Stem Cells Improve Ovarian Function in Chemotherapy-Induced Premature Ovarian Failure Mice Through Inhibiting Apoptosis and Inflammation via a Paracrine Mechanism.Reproductive Sciences (IF 2.924) Pub Date : 2021-03-09 ,DOI:10.1007/s43032-021-00499-1Taoran Deng,Jing He,Qingyun Yao,Linjing Wu,Liru Xue,Mingfu Wu,Dongcheng Wu,Changyong Li,Yufeng LiHuman umbilical cord mesenchymal stem cell (UC-MSC) application is a promising arising therapy for the treatment of premature ovarian failure (POF). However, little is known about the inflammation regulatory effects of human umbilical cord MSCs (UC-MSCs) on chemotherapy-induced ovarian damage, regardless of in vivo or in vitro. This study was designed to investigate the therapeutic effects of UC-MSC ...
-
Duration and quality of sleep during pregnancy are associated with preterm birth and small for gestational age: A prospective studyInternational Journal of Gynecology & Obstetrics (IF 4.447) Pub Date : 2021-01-09 ,DOI:10.1002/ijgo.13584Run Li, Ju Zhang, Yan Gao, Yiqi Zhang, Xi Lan, Hongli Dong, Cheng Wu, Chengwei Yu, Min Peng, Guo ZengTo explore the associations of duration and quality of sleep during pregnancy with preterm birth and small for gestational age (SGA). ...
-
Identification of Primary and Metastatic Lung Cancer-Related lncRNAs and Potential Targeted Drugs Based on ceRNA NetworkFrontiers in Oncology (IF 5.738) Pub Date : 2020-12-21 ,DOI:10.3389/fonc.2020.628930Siyao Dong, Cheng Wu, Chengyan Song, Baocui Qi, Lu Liu, Yan Xu
Lung cancer metastasis is the leading cause of poor prognosis and death for patients. Long noncoding RNAs (lncRNAs) have been validated the close correlation with lung cancer metastasis, but few comprehensive analyses have reported the specific association between lncRNA and cancer metastasis, especially via both competing endogenous RNA (ceRNA) regulatory relationships and functional regulatory networks
...
-
[Comparison of four methods for extracting extracellular vesicles from human umbilical cord mesenchymal stem cells].Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology Pub Date : 2020-10-01 ,DOI:Jing He,Taoran Deng,Changyong Li,Yufeng Li,Dongcheng Wu,Mingfu WuObjective To compare the efficiency of four methods for extracting extracellular vesicles (EVs) from human umbilical cord mesenchymal stem cells(hUCMSCs). Methods EVs were isolated from the conditioned medium of hUCMSCs by ultracentrifugation (group A), or ultrafiltration combined with ultracentrifugation (group B), or ultrafiltration combined with polyethylene glycol precipitation (group C), or ultrafiltration ...
-
Intrauterine transplantation of autologous menstrual blood stem cells increases endometrial thickness and pregnancy potential in patients with refractory intrauterine adhesion.The Journal of Obstetrics and Gynaecology Research (IF 1.697) Pub Date : 2020-08-27 ,DOI:10.1111/jog.14449Hailan Ma,Mengting Liu,Yufeng Li,Wei Wang,Keqin Yang,Lanying Lu,Mei He,Taoran Deng,Meiling Li,Dongcheng WuThis study was designed to evaluate the effects of intrauterine transplantation of menstrual blood stem cells (MenSCs) on endometrial thickness and pregnancy outcomes in patients with refractory intrauterine adhesion (IUA). ...
-
Intrauterine transplantation of autologous menstrual blood stem cells increases endometrial thickness and pregnancy potential in patients with refractory intrauterine adhesionJournal of Obstetrics and Gynaecology Research Pub Date : 2020-08-27 ,DOI:10.1111/jog.14449Hailan Ma, Mengting Liu, Yufeng Li, Wei Wang, Keqin Yang, Lanying Lu, Mei He, Taoran Deng, Meiling Li, Dongcheng WuThis study was designed to evaluate the effects of intrauterine transplantation of menstrual blood stem cells (MenSCs) on endometrial thickness and pregnancy outcomes in patients with refractory intrauterine adhesion (IUA). ...
-
Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis.Stem Cell Research & Therapy (IF 8.079) Pub Date : 2020-08-03 ,DOI:10.1186/s13287-020-01852-yE Xiang,Bing Han,Quan Zhang,Wei Rao,Zhangfan Wang,Cheng Chang,Yaqi Zhang,Chengshu Tu,Changyong Li,Dongcheng Wu
Diabetic nephropathy (DN) is one of the most serious complications of diabetes and the leading cause of end-stage chronic kidney disease. Currently, there are no effective drugs for treating DN. Therefore, novel and effective strategies to ameliorate DN at the early stage should be identified. This study aimed to explore the effectiveness and underlying mechanisms of human umbilical cord mesenchymal
...
-
Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorate Nephrocyte Injury and Proteinuria in a Diabetic Nephropathy Rat Model.Journal of Diabetes Research (IF 4.061) Pub Date : 2020-04-29 ,DOI:10.1155/2020/8035853Lian Chen,E Xiang,Changyong Li,Bing Han,Quan Zhang,Wei Rao,Cuihong Xiao,Dongcheng Wu
Mesenchymal stem cells (MSCs) are shown to alleviate renal injury of diabetic nephropathy (DN) in rats. However, the underlying mechanism of this beneficial effect is not fully understood. The aims of this study are to evaluate effects of umbilical cord-derived mesenchymal stem cells (UC-MSCs) on renal cell apoptosis in streptozotocin- (STZ-) induced diabetic rats and explore the underlying mechanisms
...
-
Multiple umbilical cord-derived MSCs administrations attenuate rat osteoarthritis progression via preserving articular cartilage superficial layer cells and inhibiting synovitis.Journal of Orthopaedic Translation (IF 4.889) Pub Date : 2020-04-23 ,DOI:10.1016/j.jot.2020.03.007Wei Tong,Xiaoguang Zhang,Quan Zhang,Jiarui Fang,Yong Liu,Zengwu Shao,Shuhua Yang,Dongcheng Wu,Xiaoming Sheng,Yingze Zhang,Hongtao Tian
Background/objectives Articular cartilage erosion probably plays a substantial role in osteoarthritis (OA) initiation and development. Studies demonstrated that umbilical cord–derived mesenchymal stem cells (UCMSCs) could delay chondrocytes apoptosis and ameliorate OA progression in patients, but the detailed mechanisms are largely uncharacterised. In this study, we aimed to study the effects of UCMSCs
...
-
Wnt10b-overexpressing umbilical cord mesenchymal stem cells promote critical size rat calvarial defect healing by enhanced osteogenesis and VEGF-mediated angiogenesis.Journal of Orthopaedic Translation (IF 4.889) Pub Date : 2020-03-28 ,DOI:10.1016/j.jot.2020.02.009Yong Liu,Jiarui Fang,Quan Zhang,Xiaoguang Zhang,Yulin Cao,Wei Chen,Zengwu Shao,Shuhua Yang,Dongcheng Wu,Man Hung,Yingze Zhang,Wei Tong,Hongtao Tian
Background/objectives Accelerating the process of bone regeneration is of great interest for surgeons and basic scientists alike. Recently, umbilical cord mesenchymal stem cells (UCMSCs) are considered clinically applicable for tissue regeneration due to their noninvasive harvesting and better viability. Nonetheless, the bone regenerative ability of human UCMSCs (HUCMSCs) is largely unknown. This study
...
-
Interleukin-1 causes CNS inflammatory cytokine expression via endothelia-microglia bi-cellular signalingBrain, Behavior, and Immunity (IF 19.227) Pub Date : 2019-10-01 ,DOI:10.1016/j.bbi.2019.06.026Zhu, Xiaoyu Liu, Daniel P. Nemeth, Damon J. DiSabato, Kristina G. Witcher, Daniel B. Mckim, Braedan Oliver, Xi Le, Gowthami Gorantla, Olimpia Berdysz, Jiaoni Li, Aishwarya D. Ramani, Zhibiao Chen, Dongcheng Wu, Jonathan P. Godbout, Ning Quan
As a major producer of the inflammatory cytokine interleukin-1 (IL-1), peripheral macrophages can augment IL-1 expression via type 1 IL-1 receptor (IL-1R1) mediated autocrine self-amplification. In the CNS, microglial cells are the major producers of inflammatory cytokines, but express negligible levels of IL-1R1. In the present study, we showed CNS IL-1 induced microglial proinflammatory cytokine
...
-
Correction to: CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized miceRetrovirology (IF 3.768) Pub Date : 2019-07-23 ,DOI:10.1186/s12977-019-0482-1Qiaoqiao Xiao, Shuliang Chen, Qiankun Wang, Zhepeng Liu, Shuai Liu, Huan Deng, Wei Hou, Dongcheng Wu, Yong Xiong, Jiafu Li, Deyin Guo
Following publication of their article [1], the authors realized that they inadvertently omitted the contribution of Dr. Li Wu (Ohio State University) who commented on the manuscript at the early stage of the manuscript preparation and provided one plasmid related to this work.
...
-
CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized miceRetrovirology (IF 3.768) Pub Date : 2019-06-11 ,DOI:10.1186/s12977-019-0477-yQiaoqiao Xiao, Shuliang Chen, Qiankun Wang, Zhepeng Liu, Shuai Liu, Huan Deng, Wei Hou, Dongcheng Wu, Yong Xiong, Jiafu Li, Deyin Guo
BackgroundThe chemokine receptor CCR5, which belongs to the superfamily of G protein-coupled receptors, is the major co-receptor for HIV-1 entry. Individuals with a homozygous CCR5Δ32 mutation have a long lasting and increased resistance to HIV-1 infection. Therefore, CCR5 represents an optimal target for HIV-1/AIDS gene therapy. The CRISPR/Cas9 system has been developed as one of the most efficacious
...
-
Differential expression of adipokines in the synovium and infrapatellar fat pad of osteoarthritis patients with and without metabolic syndrome.Connective Tissue Research (IF 3.342) Pub Date : 2019-05-29 ,DOI:10.1080/03008207.2019.1620221Bo Liu,Yu-Hang Gao,Ning Dong,Cheng-Wu Zhao,Yi-Fan Huang,Jian-Guo Liu,Xin QiObjective: To evaluate the expression levels of adipokines in the synovium and infrapatellar fat pad (IPFP) in osteoarthritis (OA) patients with and without metabolic syndrome (MetS). Methods: 120 female patients with OA were enrolled, and 60 healthy women matched body mass index, age, and sex, served as controls. Adipokines levels were measured using a sandwich enzyme-linked immunosorbent assay of ...
-
Alterations in expression levels of genes in p53-related pathways determined using RNA-Seq analysis in patients with breast cancer following CIK therapy.Oncology Letters (IF 3.111) Pub Date : 2018-01-19 ,DOI:10.3892/ol.2017.7205Zuowei Hu,Xiaoye Zhang,Hang Yang,Shuanglai Qin,Yaqi Liu,Wei Xiong,Bing Yuan,Liping Li,Weiqi Yao,Dongcheng Wu
The present study aimed at investigating the underlying molecular mechanisms for patients following cytokine-induced killer (CIK) therapy, particularly involving the alterations in p53-associated signaling pathways, to elucidate whether CIK therapy serves a function in cancer treatment. Samples of blood were collected from patients with breast cancer prior to and following CIK therapy. Two group samples
...
-
ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation.Journal of Cellular Biochemistry (IF 4.48) Pub Date : 2017-10-24 ,DOI:10.1002/jcb.26428Yuhong Ma,Sen Yuan,Xuezhang Tian,Shanchuan Lin,Shangmou Wei,Tongtong Hu,Shiyou Chen,Xueqing Li,Shuliang Chen,Dongcheng Wu,Min Wang,Deyin GuoABIN1, an important immune regulator, has been shown to be involved in various cellular functions, such as immunity, development, tissue homeostasis, and tumor progression. It inhibits TNF- and TLR-induced NF-κB signaling activation and the consequent gene expression. Despite its functional significance, the mechanism of ABIN1 in the regulation of various cellular functions remains unclear. In this ...
-
Retinoids Regulate Adipogenesis Involving the TGFβ/SMAD and Wnt/β-Catenin Pathways in Human Bone Marrow Mesenchymal Stem Cells.International Journal of Molecular Sciences (IF 6.208) Pub Date : 2017-04-20 ,DOI:10.3390/ijms18040842Jun Cao,Yuhong Ma,Weiqi Yao,Xiaoye Zhang,Dongcheng Wu
Retinoids may regulate cell differentiation as ligands of retinoic acid receptors (RARs) and/or retinoid X receptors (RXRs). We showed that RAR agonists promoted adipogenesis by upregulating the expression of CCAAT/enhancer-binding protein β (C/EBPβ) in the early stages, but blocked adipogenesis at a later stage in human bone marrow mesenchymal stem cells (hBMSCs). RXR agonists promoted adipogenesis
...
-
Retinoids Regulate Adipogenesis Involving the TGFβ/SMAD and Wnt/β-Catenin Pathways in Human Bone Marrow Mesenchymal Stem CellsInternational Journal of Molecular Sciences (IF 4.556) Pub Date : 2017-04-15 ,DOI:10.3390/ijms18040842Jun Cao, Yuhong Ma, Weiqi Yao, Xiaoye Zhang, Dongcheng Wu
Retinoids may regulate cell differentiation as ligands of retinoic acid receptors (RARs) and/or retinoid X receptors (RXRs). We showed that RAR agonists promoted adipogenesis by upregulating the expression of CCAAT/enhancer-binding protein β (C/EBPβ) in the early stages, but blocked adipogenesis at a later stage in human bone marrow mesenchymal stem cells (hBMSCs). RXR agonists promoted adipogenesis
...
-
An Energy-Efficient ECC Processor of UHF RFID Tag for Banknote Anti-CounterfeitingIEEE Access (IF 3.476) Pub Date : 2017-01-01 ,DOI:10.1109/access.2016.2615003Xi Tan, Mianxiong Dong, Cheng Wu, Kaoru Ota, Junyu Wang, Daniel W. Engels
In this paper, we present the design and analysis of an energy-efficient 163-b elliptic curve cryptographic (ECC) processor suitable for passive ultrahigh frequency (UHF) radio frequency identification (RFID) tags that are usable for banknote authentication and anti-counterfeiting. Even partial public key cryptographic functionality has long been thought to consume too much power and to be too slow
...
-
Long non-coding RNA AK058003, as a precursor of miR-15a, interacts with HuR to inhibit the expression of γ-synuclein in hepatocellular carcinoma cells.Oncotarget Pub Date : 2016-12-31 ,DOI:10.18632/oncotarget.14276Xiaoqin He,Yongfa Zheng,Yuefeng Zhang,Yuanyuan Gan,Yujie Zhou,Huilin Liang,Dongcheng Wu,Wei Ge,Junjian Deng,Ximing Xu
Long non-coding RNAs (lncRNAs) have been identified as critical players in multiple cancers and lncRNAs are tightly linked to cancer progression. However, only little amount of lncRNAs have been identified to participate in the molecular mechanisms of the progression of hepatocellular carcinoma. In this study, we found that lncRNA-AK058003 is down-regulated in hepatocellular carcinoma tissues and it
...
-
Long non-coding RNA AK058003, as a precursor of miR-15a, interacts with HuR to inhibit the expression of γ-synuclein in hepatocellular carcinoma cellsOncotarget Pub Date : 2016-12-27 ,DOI:10.18632/oncotarget.14276Xiaoqin He, Yongfa Zheng, Yuefeng Zhang, Yuanyuan Gan, Yujie Zhou, Huilin Liang, Dongcheng Wu, Wei Ge, Junjian Deng, Ximing Xu
Long non-coding RNAs (lncRNAs) have been identified as critical players in multiple cancers and lncRNAs are tightly linked to cancer progression. However, only little amount of lncRNAs have been identified to participate in the molecular mechanisms of the progression of hepatocellular carcinoma. In this study, we found that lncRNA-AK058003 is down-regulated in hepatocellular carcinoma tissues and it
...
-
Tissue factor is strongly expressed in pericarcinomatous tissue in patients with laryngeal carcinoma.International journal of clinical and experimental pathology Pub Date : 2016-01-02 ,DOI:Bin Wang,Sufang Xiong,Qingquan Hua,Chen Chen,Hua Liao,Liu Chen,Weiqi Yao,Dongcheng Wu,Zezhang TaoOBJECTIVE This study aimed to understand the relationship between tissue factor (TF) and laryngeal carcinoma. METHODS Differences in TF expression between pericarcinomatous and carcinomatous tissues were studied in patients with laryngeal carcinoma; the potential clinical significance of the observed differences is discussed. Immunohistochemical, western blot, and RT-PCR analyses were performed to ...
-
Human adipose-derived mesenchymal stem cells repair cisplatin-induced acute kidney injury through antiapoptotic pathways.Experimental and Therapeutic Medicine (IF 2.751) Pub Date : 2015-12-02 ,DOI:10.3892/etm.2015.2505Weiqi Yao,Qinyong Hu,Yuhong Ma,Wenping Xiong,Tingting Wu,Jun Cao,Dongcheng Wu
Cisplatin has been hypothesized to induce nephrotoxicity through triggering the apoptosis of tubular cells; however, the drug remains widely administered for the treatment of tumors. Recently, mesenchymal stem cells (MSCs) have been demonstrated to protect the kidney from the adverse effects induced by cisplatin. The aim of the present study was to investigate the mechanisms underlying the protective
...
-
A Two-stage Clustered Multi-Task Learning method for operational optimization in Chemical Mechanical PolishingJournal of Process Control (IF 3.951) Pub Date : 2015-11-01 ,DOI:10.1016/j.jprocont.2015.06.005Yunqiang Duan, Min Liu, Mingyu Dong, Cheng WuAbstract Operational optimization of Chemical Mechanical Polishing, which sets the proper polishing time, is very important for improving the production efficiency of semiconductor manufacturing processes. However, usual operational optimization methods based on Run-to-Run strategies have not been suitable for the mixed-product processing mode of CMP. Also, under the mode, it is very difficult to model ...
-
Integrated cavity output spectroscopy by using a sub-centimeter short optical cavity combined with a free-running Fabry–Perot diode laserApplied Physics B (IF 2.171) Pub Date : 2015-09-09 ,DOI:10.1007/s00340-015-6214-xXiutao Lou, Yongkang Dong, Dongcheng Wu, Jiatian Wei, Zhiwei LuIn integrated cavity output spectroscopy (ICOS), a long optical cavity is often required for suppressing mode structure, which, however, blocks its application for fabricating compact gas sensors requiring gas cells with the volume at milliliter level or less. In this paper, we demonstrate that low-cost free-running Fabry–Perot diode lasers have intrinsic capability for promoting suppression of cavity ...
广告：喜“文”乐“荐”|邀请好友使用Taylor & Francis Editing Services编辑润色服务，共享专属优惠！推荐人数无限制！
高级搜索
我的搜索条件
京公网安备 11010802027423号