- 作 者: "ling he"
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Facile synthesis of KaCs1-aPbBr3@ molecular sieve SBA-15 composite with improved luminescence and wet/thermal stabilityColloids and Surfaces A: Physicochemical and Engineering Aspects (IF 4.539) Pub Date : 2022-05-21 ,DOI:10.1016/j.colsurfa.2022.129258Qizheng Dong, Binglong Tian, Wenbo Zhang, Ling HeCsPbX3 (X=Cl, Br, I) perovskite quantum dots (PeQDs) have excellent properties, which makes it the most promising optoelectronic materials for the next generation of light-emitting diodes (LEDs) and display devices fields. However, CsPbX3 PeQDs have poor-term stability and easily decompose in moist or heat conditions. In this paper, the KaCs1-aPbBr3@SBA-15 composite was prepared at room temperature ...
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Naoluo Xintong Decoction in the Treatment of Ischemic Stroke: A Network Analysis of the Mechanism of ActionFrontiers in Pharmacology (IF 5.81) Pub Date : 2022-05-20 ,DOI:10.3389/fphar.2022.809505Ni Wang, Furui Chu, Changyi Fei, Lingyu Pan, Yongzhong Wang, Weidong Chen, Daiyin Peng, Xianchun Duan, Ling HeThe mechanism of action of Naoluo Xintong decoction (NLXTD) for the treatment of ischemic stroke (IS) is unknown. We used network analysis and molecular docking techniques to verify the potential mechanism of action of NLXTD in treating IS. The main active components of NLXTD were obtained from the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database, and IS targets were collected from ...
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Enhancement of Dissolving Capacity and Reducing Gastric Mucosa Irritation by Complex Formation of Resibufogenin with β-Cyclodextrin or 2-Hydroxypropyl-β-cyclodextrinMolecules (IF 4.411) Pub Date : 2022-05-17 ,DOI:10.3390/molecules27103213Nan Liu, Huan-Ping Chen, Zi-Meng Yang, Ming-Yu Xia, Dong Wang, Ling-He Zang, Dong-Chun LiuResibufogenin (RBG) is a natural medicinal ingredient with promising cardiac protection and antitumor activity. However, poor solubility and severe gastric mucosa irritation restrict its application in the pharmaceutical field. In this study, the inclusion complex of RBG with β-cyclodextrin (β-CD) and 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) was prepared using the co-evaporation method, and the molar ...
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An improved numerical model of ski-jump flood discharge atomizationJournal of Mountain Science (IF 1.55) Pub Date : 2022-05-14 ,DOI:10.1007/s11629-021-7158-8Ji-jian Lian, Shu-guang Zhang, Jun-ling HeAtomizing rainfall caused by flood discharge of high dams poses a great threat to the safety of powerhouse and ecological environment. As an indispensable means, numerical calculation is widely used in the safety design of discharge structures. The distribution of rainfall intensity is closely related to the trajectory nappe shape, jet trajectory distances, the splashed water droplet diameter and its ...
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CircHIPK3 alleviates inflammatory response and neuronal apoptosis via regulating miR-382-5p/DUSP1 axis in spinal cord injuryTransplant Immunology (IF 1.708) Pub Date : 2022-04-29 ,DOI:10.1016/j.trim.2022.101612Ximeng Yin, Wei Zheng, Ling He, Shengkai Mu, Yongle Shen, Jingxu WangBackground Spinal cord injury (SCI) is one of the serious neurological diseases with high morbidity which may be treated with hematopoietic stem cell (HSC) transplants. Circular RNAs (circRNAs) play vital roles in SCI. The study aimed to reveal the function and mechanism of circRNA homeodomain interacting protein kinase 3 (HIPK3) in SCI. Methods SCI model in vitro was established by treating neuronal ...
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Expression-based Genome-Wide Association Study Links OPN and IL1-RA with Newly Diagnosed Type 1 Diabetes in Children.The Journal of clinical endocrinology and metabolism Pub Date : 2022-04-23 ,DOI:10.1210/clinem/dgac256Xiaofan Jia,Kyoko Toda,Ling He,Dongmei Miao,Satoru Yamada,Liping Yu,Keiichi KodamaCONTEXT Islet autoantibodies (IAbs) are currently most reliable indicators of islet autoimmunity. However, IAbs do not fully meet the need for the prediction and intervention of type 1 diabetes (T1D). Serological proteins should be great sources for biomarkers. OBJECTIVE Identify new proteomic biomarkers with the technology of expression-based genome-wide association study (eGWAS) in newly diagnosed ...
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Intensity-modulated radiotherapy with more than 60 Gy improved the survival of inoperable patients with locally advanced esophageal squamous cell carcinoma: A population-based real-world studyMedicine (IF 1.889) Pub Date : 2022-04-22 ,DOI:10.1097/md.0000000000029166Wei Zhang, Qing Xie, Bifa Zhu, Xiaokang Wang, Ling He, Yong ZhangDepartment of Radiation and Medical Oncology, Central Hospital of Xianning City, Tongji Xianning Hospital of Huazhong University of Science and Technology, Xianning, China.Intensity-modulated radiotherapy (IMRT) is widely applied during the treatment of esophageal squamous cell carcinoma (ESCC), but the optimal radiation dose still lacks a consensus. The aim of this study was to explore the optimal radiation dose for inoperable locally advanced ESCC patients treated with IMRT in a real-world clinical setting. A total of 90 inoperable ESCC patients with locally advanced ...
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Degree of constantly curved holomorphic 2-spheres in the complex Grassmannians G(2,n+2;C)arXiv - MATH - Differential Geometry Pub Date : 2022-04-18 ,DOI:arxiv-2204.08116Ling HeWe show that the degree of the linearly full constantly curved holomorphic 2-spheres in the complex Grassmannians G(2,n+2;C) is greater than or equal to n for general n and less than or equal to 2n for n=2,3. ...
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Degree of constantly curved holomorphic 2-spheres in the complex Grassmannians G(2,n+2;C)arXiv - MATH - Complex Variables Pub Date : 2022-04-18 ,DOI:arxiv-2204.08116Ling HeWe show that the degree of the linearly full constantly curved holomorphic 2-spheres in the complex Grassmannians G(2,n+2;C) is greater than or equal to n for general n and less than or equal to 2n for n=2,3. ...
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Design, synthesis, and evaluation of a novel series of mono-indolylbenzoquinones derivatives for the potential treatment of breast cancerEuropean Journal of Medicinal Chemistry (IF 6.514) Pub Date : 2022-04-16 ,DOI:10.1016/j.ejmech.2022.114375Jingjing Jia, Honglu Yin, Chen Chen, Mingli Hu, Qiu Zhong, Shilong Zheng, Wei Zhang, Haibo Li, Liang Xu, Guangdi Wang, Ling HeBreast cancer is one of the most common cancers in the world, and pro-apototic drugs activating the apoptotic pathway are a strategy for anticancer therapy. To explore new antineoplastic agents, a series of novel mono-indolylbenzoquinone derivatives have been designed and synthesized. Compared with the lead bis-indolylbenzoquinones, most of the novel mono-indolylbenzoquinone derivatives have significantly ...
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Analysis of Clinicopathological Factors Associated with Radiation-Induced Cystitis in Patients with Cervical CancerJournal of Healthcare Engineering (IF 2.682) Pub Date : 2022-04-15 ,DOI:10.1155/2022/6216072Ling He, Zhenyu Wang, Jianhui Chen, Ling Chen, Peijuan Chen, Wenzhi Cai
Objective. To analyze the clinicopathological characteristics associated with radiation-induced cystitis (RIC) in patients with cervical cancer treated with chemoradiotherapy (CRT) alone or postoperational (post-op) CRT. Methods. 107 patients with cervical cancer were retrospectively recruited into the study. The surgical status, FIGO staging, total and fractionated doses of radiotherapy (RT), and
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A novel ZnWO4/MgWO4 n-n heterojunction with enhanced sonocatalytic performance for the removal of methylene blue: Characterizations and sonocatalytic mechanismSurfaces and Interfaces (IF 4.837) Pub Date : 2022-04-15 ,DOI:10.1016/j.surfin.2022.101980Ling-Ling He, Xiao-Yan Li, Jing-Yi Bai, Song Li, Shuang Qi, Xin Wang, Yu LiA novel ZnWO4/MgWO4 n-n heterojunction (0.9% ZnWO4/MgWO4) was fabricated successfully and characterized by different techniques. The methylene blue (MB) was removed to confirm the sonocatalytic activity by the 0.9% ZnWO4/MgWO4 composite. The sonocatalytic removal ratio of MB using MgWO4 was 40.04±4.34(%). It was significantly increased to 93.82±3.44(%) in the presence of 0.9% ZnWO4/MgWO4 composite ...
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Energetic material derivatives of insoluble 3,4,5-triamino-1-tetrazolyl-1,2,4-triazole (TATT)Journal of Molecular Structure (IF 3.196) Pub Date : 2022-04-15 ,DOI:10.1016/j.molstruc.2022.133099Chun-Mei Xu, Shuang-Long Wang, Wen-Li Yuan, Lei Zhang, Hangyu Liu, Guo-Hong Tao, Ling HeThe energetic derivatives of nitrogen-rich 3,4,5-triamino-1-tetrazolyl-1,2,4-triazolium (TATT) cation combined with nitrate (1), chloride (2) and perchlorate (3) anions were synthesized from the reaction of 3,4,5-triamino-1-tetrazolyl-1,2,4-triazole with various acids. All salts were characterized by IR, NMR and elemental analysis. Their structures were verified by single-crystal X-ray diffraction ...
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Comparative functional analysis of malate metabolism genes in Oenococcus oeni and Lactiplantibacillus plantarum at low pH and their roles in acid stress responseFood Research International (IF 6.475) Pub Date : 2022-04-14 ,DOI:10.1016/j.foodres.2022.111235Qiling Chen, Nan Hao, Lili Zhao, Xiangke Yang, Yuxin Yuan, Yuzhu Zhao, Fu Wang, Zuobing Qiu, Ling He, Kan Shi, Shuwen LiuOenococcus oeni and Lactiplantibacillus plantarum are major wine-associated lactic acid bacteria that positively influence wine by carrying out malolactic fermentation. O. oeni is the most widely used commercial starter in winemaking because of its fast and efficient malate metabolism capacity under harsh wine conditions. To date, very little is known about the specific molecular mechanism underlying ...
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Naoluo Xintong Decoction Ameliorates Cerebral Ischemia-Reperfusion Injury by Promoting Angiogenesis through Activating the HIF-1α/VEGF Signaling Pathway in RatsEvidence-based Complementary and Alternative Medicine (IF 2.629) Pub Date : 2022-04-11 ,DOI:10.1155/2022/9341466Pei-Pei Li, Ling He, Li-Miao Zhang, Xue-Mei Qin, Jian-Peng Hu
Background. Naoluo Xintong decoction (NLXTD) is a traditional Chinese medicine (TCM) formula which has been used to improve neuronal functional recovery after cerebral ischemic stroke. However, the molecular mechanism underlying NLXTD’s amelioration of ischemic stroke remains unclear. The present study was designed to explore the effect and mechanism of NLXTD on brain angiogenesis in a rat model with
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Pore-scale investigation on the multi-component gas adsorption and diffusion in carbon xerogel microporous structure using molecular simulation methodsMicroporous and Mesoporous Materials (IF 5.455) Pub Date : 2022-04-08 ,DOI:10.1016/j.micromeso.2022.111890Jia-Peng Dai, Dong Li, Ya-Ling He, Shen Du, Jun-Ning LiThe atomic model of carbon xerogel microporous structure is reconstructed by a modified virtual porous carbon (VPC) model. The physical parameters of the reconstructed model, especially the predicted nitrogen adsorption isotherm, agree well with the experimental data. Then, the adsorption and diffusion of the gas in carbon xerogel microporous structure are investigated at the pore-scale. The results ...
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Conspecific disturbance odors act as alarm cues to affect female mate choice in a treefrogBehavioral Ecology and Sociobiology (IF 2.98) Pub Date : 2022-04-08 ,DOI:10.1007/s00265-022-03164-yKe Deng, Ya Zhou, Hao-Di Zhang, Qiao-Ling He, Bi-Cheng Zhu, Tong-Liang Wang, Ji-Chao Wang, Wouter Halfwerk, Jian-Guo CuiAbstract Mate choice in frogs depends heavily on acoustic communication, and females in many species possess an inherent preference for longer and/or more complex calls. Recently, it has become clear that conspecific chemical cues can also be useful in attracting potential mates in anuran species. However, how conspecific chemical cues influence mate choice decisions when paired with acoustic signals ...
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Development and optimization of Lysis gene E as a counter-selection marker with high stringencyBiotechnology Journal (IF 4.677) Pub Date : 2022-04-04 ,DOI:10.1002/biot.202100423Wei Chen, Ruyi Chen, Ling He, Xiaotong WuSeamless modification of bacterial chromosomes is widely performed in both theoretical and practical research. For this purpose, excellent counter-selection marker genes with high stringency are needed. ...
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Clinical features and prognostic analysis of posterior reversible encephalopathy syndrome in childrenInternational Journal of Developmental Neuroscience (IF 2.457) Pub Date : 2022-04-04 ,DOI:10.1002/jdn.10184Ting Deng, Xinyu Zhang, Xiaoling Peng, Hailun Peng, Ling He, Yue HuWe aimed to investigate the clinical features and prognosis of posterior reversible encephalopathy syndrome (PRES) in children. ...
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Clinical features and prognostic analysis of posterior reversible encephalopathy syndrome in children.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience Pub Date : 2022-04-04 ,DOI:10.1002/jdn.10184Ting Deng,Xinyu Zhang,Xiaoling Peng,Hailun Peng,Ling He,Yue HuBACKGROUND We aimed to investigate the clinical features and prognosis of posterior reversible encephalopathy syndrome (PRES) in children. METHODS Clinical data of children with PRES diagnosed at the Children's Hospital of Chongqing Medical University from June 2015 to May 2019 were retrospectively analyzed. RESULTS The study enrolled 47 patients with a mean age at diagnosis of 8.79 ± 3.72 years (range ...
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Bidentate Ligand-Induced Oriented Transformation of CsPbBr3 Perovskite Nanocrystals into Nanowires for X-ray PhotodetectorsACS Applied Nano Materials (IF 5.097) Pub Date : 2022-03-29 ,DOI:10.1021/acsanm.2c00642Chunyu Zhao, Zaozhen He, Peihua Wangyang, Jie Tan, Chengyu Shi, Aizhao Pan, Ling He, Yi LiuShape and dimensionality control by ligands is an efficient way to fabricate high-quality perovskite nanocrystals (NCs) with optoelectronic properties. Herein, to realize oriented transformations between different morphologies of CsPbBr3 nanocrystals, we conceived of the use of defects and bidentate ligands to synergistically drive the reorientation of CsPbBr3 nanocrystals into CsPbBr3 nanowires (NWs) ...
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Research progress on antineoplastic, antibacterial, and anti-inflammatory activities of seven-membered heterocyclic derivatives.Current Medicinal Chemistry (IF 4.53) Pub Date : 2022-03-28 ,DOI:10.2174/0929867329666220328123953Bin Li,Chen Chen,Jingjing Jia,Ling HeDepartment of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, ChinaSeven-membered heterocyclic compounds are important drug scaffolds, because of their unique chemical structures. They widely exist in natural products and show a variety of biological activities. They have commonly been used in central nervous system drugs in the past 30 years. In the past decade, there are many studies on the activities of antitumor, antibacterial, etc. Herein, we summarize the research ...
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Clinical significance of high mobility group box 1/toll-like receptor 4 in obese diabetic patientsEndocrine Journal (IF 2.349) Pub Date : 2022-03-28 ,DOI:10.1507/endocrj.ej21-0381Shuai Liu, Xianchun Wang, Yue Kai, Chenrui Tian, Sheng Guo, Ling He, Desheng Zhai, Xiangfeng Song
High mobility group box 1 (HMGB1) is an alarmin that may link to obesity and type 2 diabetes mellitus (T2DM). The present study analyzed the correlation between HMGB1/ Toll-like receptor 4 (TLR4) and certain biochemical parameters in obese (OB) diabetic patients. 40 normal glucose tolerant subjects (NGT) and 40 patients with newly diagnosed T2DM were enrolled. All patients were further divided into
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Urinary galectin-3 binding protein (G3BP) as a biomarker for disease activity and renal pathology characteristics in lupus nephritisArthritis Research & Therapy (IF 5.156) Pub Date : 2022-03-28 ,DOI:10.1186/s13075-022-02763-4Ding, Huihua, Shen, Yiwei, Lin, Cheng, Qin, Ling, He, Shijun, Dai, Min, Okitsu, Shinji L., DeMartino, Julie A., Guo, Qiang, Shen, Nan
There is an urgent need to identify novel biomarkers of LN to reflect renal histological changes. This study aims to investigate urinary G3BP levels in LN patients and their association with renal disease activity both clinically and pathologically. This is a cross-sectional study. A total of 119 lupus nephritis patients were recruited. Thirty patients with chronic kidney diseases (CKD) and 27 healthy
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The Mechanism of Particle Impact-Assisted Rock Cutting in Hard Brittle GraniteArabian Journal for Science and Engineering (IF 2.334) Pub Date : 2022-03-26 ,DOI:10.1007/s13369-022-06723-7Xiaohua Zhu, Ling He, Weiji Liu, Shiqiang Wang, Yunxu LuoThe deep rocks generally present high strength, plasticity and abrasiveness, which greatly limit the efficient drilling of the bit. Particle impact drilling (PID) technology is a new and efficient drilling method, but its rock-breaking mechanism is still unclear. In present study, a numerical model which truly reflects the mineral composition and granule diameter distribution of granite is established ...
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SMD-Net: Siamese Multi-Scale Difference-Enhancement Network for Change Detection in Remote SensingRemote Sensing (IF 4.848) Pub Date : 2022-03-25 ,DOI:10.3390/rs14071580Xiangrong Zhang, Ling He, Kai Qin, Qi Dang, Hongjie Si, Xu Tang, Licheng Jiao
Change detection, as an important task of remote sensing image processing, has a wide range of applications in many aspects such as land use and natural disaster assessment. Recent change detection methods have achieved good results. However, due to the environmental difference between the bi-temporal images and the complicated imaging condition, there are usually problems such as missing small objects
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Application of Quantitative Susceptibility Mapping in the Assessment of Iron Content in Brain Regions in Normal Children.Current Medical Imaging (IF 0.858) Pub Date : 2022-03-25 ,DOI:10.2174/1573405618666220325090655Shilong Tang,Guanping Zhang,Xianfan Liu,Zhuo Chen,Ling HePURPOSE We evaluated brain iron content in a healthy pediatric population using quantitative susceptibility mapping (QSM). METHODS From June 2018 to December 2019, healthy subjects aged 2-18 years old (200 males, 200 females) with no anatomical abnormalities were assessed. All of the children underwent 3D T1 anatomical MRIs in addition to the sequence scans of enhanced T2 star-weighted angiography ...
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Hematological changes in neonatal mice with phlebotomy-induced anemiaPediatric Research (IF 3.756) Pub Date : 2022-03-23 ,DOI:10.1038/s41390-022-02023-wYerin Chung, Suneetha Desiraju, Kopperuncholan Namachivayam, Pierre Guzman, Ling He, Krishnan MohanKumarBackground Anemia is a nearly universal diagnosis in preterm infants, caused by phlebotomy, and exacerbated by the underlying erythropoietic immaturity. Newborn infants are exposed to the unique stressor of fetal-to-neonatal transition, which requires significant adaptation ex utero. Accordingly, the preterm infant’s response to anemia may alter the ability to confront underlying illness. This study ...
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Seminal plasma piRNA array analysis and identification of possible biomarker piRNAs for the diagnosis of asthenozoospermia.Experimental and Therapeutic Medicine (IF 2.447) Pub Date : 2022-03-23 ,DOI:10.3892/etm.2022.11275Ling He, Xingwu Wu, Rongye Wu, Ping Guo, Wenfeng He, Wanlei Sun, He ChenAsthenozoospermia (AZS) is characterized by reduced sperm motility and its pathogenesis remains poorly understood. Piwi-interacting RNAs (piRNAs) have been indicated to serve important roles in spermatogenesis. However, little is known about the correlation of piRNA expression with AZS. In the present study, small RNA sequencing (small RNA-seq) was performed on sperm samples from AZS patients and fertile ...
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Implantable Polyurethane Scaffolds Loading with PEG-Paclitaxel Conjugates for the Treatment of Glioblastoma MultiformeChinese Journal of Polymer Science (IF 3.603) Pub Date : 2022-03-21 ,DOI:10.1007/s10118-022-2695-3He-Cheng Wu, Yuan Feng, Xing-Ying Song, Chun-Yang Song, Jin-Lin Chen, Yan-Chao Wang, Xue-Ling He, Rui-Chao Liang, Jie-Hua Li, Hong TanImprovement of the treatment for Glioblastoma multiforme (GBM) especially the development of in situ controllable drug release is still a major concern. In this study, we developed waterborne biodegradable polyurethane (WBPU) scaffolds incorporated with redox-sensitive and RGD-decorated paclitaxel (PTX) polymer-drug conjugates (PDCs) for targeted GBM therapy in situ. The drug scaffolds could be implanted ...
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