- 作 者: ( "yihong chen" OR "yi-hong chen" )
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Tourism research progress: comparing tourism literature reviews published in English WOS and Chinese CNKI language journalsTourism Review (IF 7.689) Pub Date : 2023-03-17 ,DOI:10.1108/tr-06-2022-0303Tao Hu, Yihong Chen, Huimin Chen, Yangyan ZhangPurpose This study aims to expand tourism knowledge by analysing literature review articles published in English Web of Science (WOS) and Chinese China National Knowledge Infrastructure (CNKI) language journals and reviewing their influence, interconnection and trends. Design/methodology/approach A three-stage method was designed to understand the tourism research progress. Performance analysis identified ...
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A single C-terminal residue controls SARS-CoV-2 spike trafficking and virion assemblybioRxiv - Biophysics Pub Date : 2023-03-10 ,DOI:10.1101/2023.03.09.531992Debajit Dey, Enya Qing, Yanan He, Yihong Chen, Benjamin Jennings, Whitaker Cohn, Suruchi Singh, Lokesh Gakhar, Nicholas J Schnicker, Brian G Pierce, Julian P Whitelegge, Balraj Doray, John P Orban, Tom Gallagher, S Saif Hasan
The spike (S) protein of SARS-CoV-2 is delivered to the virion assembly site in the ER-Golgi Intermediate Compartment (ERGIC) from both the ER and cis-Golgi in infected cells1-3. However, the relevance and modulatory mechanism of this bidirectional trafficking are unclear. Here, using structure-function analyses, we show that S incorporation into virions and viral fusogenicity are determined by coatomer-dependent
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Membrane filtration processing of infant milk formula alters protein digestion in young pigsFood Research International (IF 7.425) Pub Date : 2023-02-09 ,DOI:10.1016/j.foodres.2023.112577Yihong Chen, Hazel Rooney, Cathal Dold, Simona Bavaro, John Tobin, Michael J. Callanan, André Brodkorb, Peadar G. Lawlor, Linda GiblinReducing heat treatment (HT) during processing of infant milk formula (IMF) is desirable to produce a product that more closely resembles breast milk. By employing membrane filtration (MEM), we produced an IMF (60:40 whey to casein ratio) at pilot scale (250 kg). MEM-IMF had a significantly higher content of native whey (59.9 %) compared to HT-IMF (4.5 %) (p < 0.001). Pigs, at 28 days old, were blocked ...
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A Multi-Omics Analysis of NASH-Related Prognostic Biomarkers Associated with Drug Sensitivity and Immune Infiltration in Hepatocellular Carcinoma.Journal of Clinical Medicine (IF 4.964) Pub Date : 2023-02-06 ,DOI:10.3390/jcm12041286Yongting Liu,Zhaohui Jiang,Xin Zhou,Yin Li,Ping Liu,Yihong Chen,Jun Tan,Changjing Cai,Ying Han,Shan Zeng,Hong Shen,Ziyang Feng
Background: Nonalcoholic steatohepatitis (NASH)-driven hepatocellular carcinoma (HCC) is becoming a major health-related problem. The exploration of NASH-related prognostic biomarkers and therapeutic targets is necessary. Methods: Data were downloaded from the GEO database. The "glmnet" package was used to identify differentially expressed genes (DEGs). The prognostic model was constructed by the univariate
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Exosomes derived from BMSCs with miR-124-3p inhibitor protects against LPS-induced endometritis through regulation of DUSP6, p-p65 and p-ERKbioRxiv - Cell Biology Pub Date : 2023-02-02 ,DOI:10.1101/2023.02.02.526752Juambing Wei, Yihong Chen, Shan Zheng, Xiumei Zhao, Yi Zhang, Suchai Yu
Endometritis seriously affects women's normal life and work. It has been found that microRNA-123-3p (miR-124-3p) expression is abnormally high expression in the patients of chronic endometritis. However, the underlying mechanism for miR-124-3p regulation of endometritis development remains unclear. In our study, we treated human endometrial epithelial cells (HEECs) with LPS to simulate endometrial
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X-ray Insights into Formation of −O Functional Groups on MXenes: Two-Step Dehydrogenation of Adsorbed WaterNano Letters (IF 12.262) Pub Date : 2023-01-30 ,DOI:10.1021/acs.nanolett.2c04712Pengjun Zhang, Hongwei Shou, Yujian Xia, Changda Wang, Shiqiang Wei, Wenjie Xu, Yihong Chen, Zehua Liu, Xin Guo, Kefu Zhu, Yuyang Cao, Xiaojun Wu, Shuangming Chen, Li SongEngineered MXene surfaces with more −O functional groups are feasible for realizing higher energy density due to their higher theoretical capacitance. However, there have been only a few explorations of this regulation mechanism. Investigating the formation source and mechanism is conducive to expanding the adjustment method from the top-down perspective. Herein, for the first time, the formation dynamics ...
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Design and characterization of a protein fold switching networkNature Communications (IF 17.694) Pub Date : 2023-01-26 ,DOI:10.1038/s41467-023-36065-3Biao Ruan, Yanan He, Yingwei Chen, Eun Jung Choi, Yihong Chen, Dana Motabar, Tsega Solomon, Richard Simmerman, Thomas Kauffman, D. Travis Gallagher, John Orban, Philip N. Bryan
To better understand how amino acid sequence encodes protein structure, we engineered mutational pathways that connect three common folds (3α, β−grasp, and α/β−plait). The structures of proteins at high sequence-identity intersections in the pathways (nodes) were determined using NMR spectroscopy and analyzed for stability and function. To generate nodes, the amino acid sequence encoding a smaller
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Identifying the role of media discourse in tourism demand forecastingCurrent Issues in Tourism (IF 7.578) Pub Date : 2023-01-17 ,DOI:10.1080/13683500.2023.2165050Yihong Chen, Tao Hu, Peiying SongABSTRACT High-frequency and timely tourism demand forecasting of fine-grained attractions is an effective tool that helps tourism stakeholders make decisions and formulate strategies. However, there are limitations due to the external sensitivity of tourism demand. This research integrated news coverage with other psychosocial variables to comprehensively explore the impact of social unrest on tourism ...
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Discrete-velocity-direction models of BGK-type with minimum entropy: II. Weighted modelsarXiv - PHYS - Fluid Dynamics Pub Date : 2023-01-16 ,DOI:arxiv-2301.06332Yihong Chen, Qian Huang, Wen-An YongIn this series of works, we develop a discrete-velocity-direction model (DVDM) with collisions of BGK-type for simulating gas flows, where the molecular motion is confined to some prescribed directions but the speed is still a continuous variable in each orientation. In this article, we introduce a weighted function in each orientation when recovering the macroscopic parameters. Moreover, the internal ...
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Discrete-velocity-direction models of BGK-type with minimum entropy: II. Weighted modelsarXiv - PHYS - Computational Physics Pub Date : 2023-01-16 ,DOI:arxiv-2301.06332Yihong Chen, Qian Huang, Wen-An YongIn this series of works, we develop a discrete-velocity-direction model (DVDM) with collisions of BGK-type for simulating gas flows, where the molecular motion is confined to some prescribed directions but the speed is still a continuous variable in each orientation. In this article, we introduce a weighted function in each orientation when recovering the macroscopic parameters. Moreover, the internal ...
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Performance estimation for the memristor-based computing-in-memory implementation of extremely factorized network for real-time and low-power semantic segmentationNeural Networks (IF 9.657) Pub Date : 2023-01-13 ,DOI:10.1016/j.neunet.2023.01.008Shuai Dong, Zhen Fan, Yihong Chen, Kaihui Chen, Minghui Qin, Min Zeng, Xubing Lu, Guofu Zhou, Xingsen Gao, Jun-Ming LiuNowadays many semantic segmentation algorithms have achieved satisfactory accuracy on von Neumann platforms (e.g., GPU), but the speed and energy consumption have not meet the high requirements of certain edge applications like autonomous driving. To tackle this issue, it is of necessity to design an efficient lightweight semantic segmentation algorithm and then implement it on emerging hardware platforms ...
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Relationship between gray matter structure and age in children and adolescents with high-functioning autism spectrum disorderFrontiers in Human Neuroscience (IF 3.473) Pub Date : 2023-01-06 ,DOI:10.3389/fnhum.2022.1039590Fenfen Sun, Yue Chen, Yingwen Huang, Jing Yan, Yihong Chen
ObjectiveThe present study used magnetic resonance imaging to investigate the difference in the relationship between gray matter structure and age in children and adolescents with autism spectrum disorder (ASD) and typically developing (TD) subjects.MethodsAfter screening T1 structural images from the Autism Brain Imaging Data Exchange (ABIDE) database, 111 children and adolescents (7–18 years old)
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PvML1 suppresses bacterial infection by recognizing LPS and regulating AMP expression in shrimpFrontiers in Immunology (IF 8.786) Pub Date : 2022-12-28 ,DOI:10.3389/fimmu.2022.1088862Yue Wang, Li-Guo Yang, Guang-Peng Feng, Zong-Li Yao, Shou-Hu Li, Jun-Fang Zhou, Wen-Hong Fang, Yi-Hong Chen, Xin-Cang Li
Toll and Toll-like receptors (TLRs) play essential roles in the innate immunity of Drosophila and mammals. Recent studies have revealed the presence of Toll-mediated immune signaling pathways in shrimp. However, the recognition and activation mechanism of Toll signaling pathways in crustaceans remain poorly understood due to the absence of key recognition molecules, such as peptidoglycan recognition
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Mini-Model Adaptation: Efficiently Extending Pretrained Models to New Languages via Aligned Shallow TrainingarXiv - CS - Machine Learning Pub Date : 2022-12-20 ,DOI:arxiv-2212.10503Kelly Marchisio, Patrick Lewis, Yihong Chen, Mikel ArtetxePrior work has shown that it is possible to expand pretrained Masked Language Models (MLMs) to new languages by learning a new set of embeddings, while keeping the transformer body frozen. Despite learning a small subset of parameters, this approach is not compute-efficient, as training the new embeddings requires a full forward and backward pass over the entire model. In this work, we propose mini-model ...
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Mini-Model Adaptation: Efficiently Extending Pretrained Models to New Languages via Aligned Shallow TrainingarXiv - CS - Computation and Language Pub Date : 2022-12-20 ,DOI:arxiv-2212.10503Kelly Marchisio, Patrick Lewis, Yihong Chen, Mikel ArtetxePrior work has shown that it is possible to expand pretrained Masked Language Models (MLMs) to new languages by learning a new set of embeddings, while keeping the transformer body frozen. Despite learning a small subset of parameters, this approach is not compute-efficient, as training the new embeddings requires a full forward and backward pass over the entire model. In this work, we propose mini-model ...
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Robust solvatochromic carbon quantum dots for selective detection of water and Sn4+ and specific lipid imagingJournal of Hazardous Materials (IF 14.224) Pub Date : 2022-11-21 ,DOI:10.1016/j.jhazmat.2022.130456Zihan Wang, Yumin Hao, Yihong Chen, Wenjuan Dong, Yang Liu, Jing Li, Hong Gao, Xu Wang, Shaomin Shuang, Chuan Dong, Xiaojuan GongDeveloping carbon quantum dots (CQDs) with the solvatochromic effect and exploring multifunctional applications remains challenging. Herein, robust solvatochromic carbon quantum dots (RS-CQDs) with emission shift up to ∼62 nm from yellow to red was fabricated by the hydrothermal method. The RS-CQDs was used to detect water and Sn4+ in the linear ranges and limits of detection of 2.0–97.6% and 0.14% ...
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Visual function and disability are associated with microcystic macular edema, macular and peripapillary vessel density in patients with neuromyelitis optica spectrum disorderFrontiers in Neurology (IF 4.086) Pub Date : 2022-11-14 ,DOI:10.3389/fneur.2022.1019959Jin Li, Yihong Chen, Ying Zhang, Zhiyong He, Huankai Yu, Ce Shi, Meixiao Shen, Fan Lu
PurposeTo assess macular and peripapillary vessel density and neurodegeneration in eyes with and without microcystic macular edema (MME) in neuromyelitis optica spectrum disorder (NMOSD) patients while investigating their association with visual impairment and disease disability.MethodsThis is a cross-sectional study. A total of 52 eyes from 29 NMOSD patients were recruited, including 8 eyes with MME
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Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancerCell Death & Disease (IF 9.685) Pub Date : 2022-11-08 ,DOI:10.1038/s41419-022-05397-1Yi-Hong Chen, Nan-Zhu Xu, Chang Hong, Wen-Qi Li, Yi-Qiong Zhang, Xin-Yi Yu, Yue-Le Huang, Jue-Yu Zhou
Myosin 1b (Myo1b) is an important single-headed membrane-associated motor of class I myosins that participate in many critical physiological and pathological processes. Mounting evidence suggests that the dysregulation of Myo1b expression has been extensively investigated in the development and progression of several tumors. However, the functional mechanism of Myo1b in CRC angiogenesis and autophagy
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Highly Efficient and Selective Photocatalytic Nonoxidative Coupling of Methane to Ethylene over Pd-Zn Synergistic Catalytic Sites.Research (IF 11.036) Pub Date : 2022-11-07 ,DOI:10.34133/2022/9831340Yanduo Liu,Yihong Chen,Wenbin Jiang,Tingting Kong,Pedro H C Camargo,Chao Gao,Yujie Xiong
Photocatalytic nonoxidative coupling of CH4 to multicarbon (C2+) hydrocarbons (e.g., C2H4) and H2 under ambient conditions provides a promising energy-conserving approach for utilization of carbon resource. However, as the methyl intermediates prefer to undergo self-coupling to produce ethane, it is a challenging task to control the selective conversion of CH4 to higher value-added C2H4. Herein, we
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Hsa_Circ_0066351 Acts as a Prognostic and Immunotherapeutic Biomarker in Colorectal CancerFrontiers in Immunology (IF 8.786) Pub Date : 2022-11-02 ,DOI:10.3389/fimmu.2022.927811Yan Gao, Yulai Zhou, Le Wei, Ziyang Feng, Yihong Chen, Ping Liu, Yinghui Peng, Qiaoqiao Huang, Le Gao, Yongting Liu, Ying Han, Hong Shen, Changjing Cai, Shan Zeng
Circular RNA (circRNA), a novel class of non-coding RNA, has been reported in various diseases, especially in tumors. However, the key signatures of circRNA-competitive endogenous RNA (ceRNA) network are largely unclear in colorectal cancer (CRC). We first characterized circRNAs profile by using circRNA-seq analysis from real-word dataset. The expression level of hsa_circ_0066351 in CRC tissues and
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Design and characterization of a protein fold switching networkbioRxiv - Biochemistry Pub Date : 2022-10-27 ,DOI:10.1101/2022.10.26.513944Biao Ruan, Yanan He, Yingwei Chen, Eun Jung Choi, Yihong Chen, Dana Motabar, Tsega Solomon, RIchard Simmerman, Thomas Kauffman, D. Travis Gallagher, John P. Orban, Philip N Bryan
Protein sequences encoding three common small folds (3α, β-grasp, and α/β-plait) were connected in a network with high-identity intersections, termed nodes. The structures of proteins around nodes were determined using NMR spectroscopy and analyzed for stability and binding function. To generate nodes, the amino acid sequence encoding a shorter fold (3α or β-grasp) is embedded in the structure of the
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Transcriptome analysis reveals the effects of dietary lipid level on growth performance and immune response in golden pompano (Trachinotus ovatus)Aquaculture (IF 5.135) Pub Date : 2022-10-23 ,DOI:10.1016/j.aquaculture.2022.738959Fei Song, Yawen Qin, Chaoqun He, Haoyu Geng, Peng Yang, Wenqiang Wang, Yihong ChenPresent study was conducted to accurately evaluate the optimal dietary lipid level in golden pompano (Trachinotus ovatus) diets combining phenotypic responses and transcriptomics analysis. Fish with initial body weight 27.65 g ± 0.17 g were fed diets with six lipid levels (9.13%, 10.59%, 12.12%, 14.98%, 16.25%, 19.26%), respectively. Results showed that dietary lipid levels significantly altered the ...
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Bimolecular Self-Trapped Exciton Formation in Bismuth VanadateThe Journal of Physical Chemistry Letters (IF 6.888) Pub Date : 2022-10-13 ,DOI:10.1021/acs.jpclett.2c02596Jinzhong Zhang, Jueli Shi, Yihong Chen, Kelvin H. L. Zhang, Ye YangBismuth vanadate (BiVO4) is a promising photoanode material for solar-driven water splitting, and knowledge of the photocarrier dynamics in BiVO4 could offer guidance to propel the development of the photoanode performance. Herein, we uncovered the nature of various photogenerated transient species in BiVO4 and extracted their respective dynamics. We found spectral and dynamic evidence that the electrons ...
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Preliminary study of the intranuclear function of Sma and Mad related protein 5 gene in Litopenaeus vannameiDevelopmental & Comparative Immunology (IF 3.605) Pub Date : 2022-10-08 ,DOI:10.1016/j.dci.2022.104564Bin-Bin Li, Jin-Quan Fan, Qian-Ming Hong, Xin-Jun Yang, Ze-Yu Yan, Wen Huang, Yi-Hong ChenLitopenaeus vannamei Smad5 (LvSmad5) in cytoplasm has been proved to be involved in environmental stress response. As LvSmad5 could also locate in nucleus under specific stress, it was conjectured that LvSmad5 might participate in environmental stress response. While, the experimental evidence is still lacking. In this study, cytosolic LvSmad5 mutant or nuclear LvSmad5 mutant was expressed in Drosophila ...
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The optimal first-line treatment for patients with left-sided RAS wild-type metastatic colorectal cancer: Double-drug regimen or triple-drug regimen therapyFrontiers in Pharmacology (IF 5.988) Pub Date : 2022-09-30 ,DOI:10.3389/fphar.2022.1015510Changjing Cai, Qingqing Luo, Yihan Liu, Yinghui Peng, Xiangyang Zhang, Zhaohui Jiang, Ziyang Feng, Yaru Qi, Yan Gao, Yongting Liu, Ping Liu, Yihong Chen, Cao Guo, Hong Shen, Shan Zeng, Ying Han
There are many treatments for metastatic colorectal cancer (mCRC). Among them, uncertainty remains especially concerning the clinical benefit of different regimens for left-sided RAS wild-type (WT) mCRC in the triple-drug therapy era. No studies have been conducted to answer this critical clinical issue. We performed a comprehensive analysis of published data and real-world data. First, we conducted
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A genetic linkage map of the Pacific white shrimp (Litopenaeus vannamei): QTL mapping for low-temperature tolerance and growth-related traits and identification of the candidate genesAquaculture (IF 5.135) Pub Date : 2022-09-15 ,DOI:10.1016/j.aquaculture.2022.738834Huijie Lu, Wei Chen, Fengkun Liu, Minwei Huang, Kai Peng, Jichen Zhao, Xiaoying Chen, Yuping Sun, Chaozheng Li, Yihong Chen, Zhenxing Liu, Huo Li, Wen HuangLow water temperature is a prevailing abiotic stress which adversely impacts global shrimp growth and production. In this study, a high-density genetic linkage map of L. vannamei was constructed using double-digest restriction site-associated DNA sequencing (ddRAD-seq) with an F1 full-sib family mapping panel comprising 148 progenies and 2 parents. A total of 2528 single-nucleotide polymorphisms (SNPs) ...
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Check and Link: Pairwise Lesion Correspondence Guides Mammogram Mass DetectionarXiv - CS - Computer Vision and Pattern Recognition Pub Date : 2022-09-13 ,DOI:arxiv-2209.05809Ziwei Zhao, Dong Wang, Yihong Chen, Ziteng Wang, Liwei WangDetecting mass in mammogram is significant due to the high occurrence and mortality of breast cancer. In mammogram mass detection, modeling pairwise lesion correspondence explicitly is particularly important. However, most of the existing methods build relatively coarse correspondence and have not utilized correspondence supervision. In this paper, we propose a new transformer-based framework CL-Net ...
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PointScatter: Point Set Representation for Tubular Structure ExtractionarXiv - CS - Computer Vision and Pattern Recognition Pub Date : 2022-09-13 ,DOI:arxiv-2209.05774Dong Wang, Zhao Zhang, Ziwei Zhao, Yuhang Liu, Yihong Chen, Liwei WangThis paper explores the point set representation for tubular structure extraction tasks. Compared with the traditional mask representation, the point set representation enjoys its flexibility and representation ability, which would not be restricted by the fixed grid as the mask. Inspired by this, we propose PointScatter, an alternative to the segmentation models for the tubular structure extraction ...
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MTFR2 shapes a barrier of immune microenvironment in hepatocellular carcinomaiScience (IF 6.107) Pub Date : 2022-09-10 ,DOI:10.1016/j.isci.2022.105095Qiaoqiao Huang, Ying Han, Edward Shen, Ziyang Feng, Yinghui Peng, Le Gao, Yan Gao, Yongting Liu, Wei Li, Ping Liu, Yihong Chen, Cao Guo, Shan Zeng, Changjing Cai, Hong Shen
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death in the world. Mitochondrial fission regulator 2 (MTFR2) is involved in the development of various cancers. However, the roles of MTFR2 in HCC remain unknown. In this study, we conducted a comprehensive analysis of MTFR2 in HCC, which was generated from integrative MTFR2 analyses of eight HCC cell lines, and three datasets (public
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Prognostic stratification based on m5C regulators acts as a novel biomarker for immunotherapy in hepatocellular carcinoma.Frontiers in Immunology (IF 8.786) Pub Date : 2022-09-09 ,DOI:10.3389/fimmu.2022.951529Ping Liu,Ziqing Zhu,Jiayao Ma,Le Wei,Ying Han,Edward Shen,Xiao Tan,Yihong Chen,Changjing Cai,Cao Guo,Yinghui Peng,Yan Gao,Yongting Liu,Qiaoqiao Huang,Le Gao,Yin Li,Zhaohui Jiang,Wantao Wu,Yihan Liu,Shan Zeng,Wei Li,Ziyang Feng,Hong Shen
Background Immunotherapy is a promising anti-cancer strategy in hepatocellular carcinoma (HCC). However, a limited number of patients can benefit from it. There are currently no reliable biomarkers available to find the potential beneficiaries. Methylcytosine (m5C) is crucial in HCC, but its role in forecasting clinical responses to immunotherapy has not been fully clarified. Methods In this study
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