- 作 者: "lei fu"
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Mechanical Properties under Compression and Microscopy Analysis of Basalt Fiber Reinforced Recycled Aggregate ConcreteMaterials (IF 3.748) Pub Date : 2023-03-22 ,DOI:10.3390/ma16062520Xianggang Zhang, Gaoqiang Zhou, Ping Xu, Lei Fu, Dapeng Deng, Xiaomei Kuang, Yuhui FanIn this study, the basalt fiber content (0%, 0.075%, and 0.15%) and replacement ratio of recycled coarse aggregate (0%, 50%, and 100%) were used as parameters, and the compressive strength of 15 cubes and 15 prisms was analyzed. The failure morphology of the specimens was characterized, and the cubic compressive strength, axial compressive strength, elastic modulus, Poisson’s ratio, and other mechanical ...
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Synthesis and Bioactivity Evaluation of a Myelin-Specific Contrast Agent for Magnetic Resonance Imaging of Myelination in Central Nervous SystemBioorganic & Medicinal Chemistry (IF 3.461) Pub Date : 2023-03-21 ,DOI:10.1016/j.bmc.2023.117257Bin Wei, Na Weng, Lei Fu, Yuxuan Li, Xu Wang, Ruijuan Yin, Tao JiangDemyelination exists in many neurological diseases of nervous system, such as stroke. Currently, magnetic resonance imaging (MRI) has been the main tool for diagnosing and monitoring the myelin related diseases. However, the conventional MRI unable to distinguish demyelinating lesions from other inflammatory lesions. To address this problem, we have designed and prepared a myelin specific magnetic ...
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2D Inorganic Framework with Self-Transforming Luminescence Centers for Multicolor EmissionACS Materials Letters (IF 11.17) Pub Date : 2023-03-17 ,DOI:10.1021/acsmaterialslett.3c00112Yabei Xia, Linyang Li, Haihui Lan, Yuxin Ma, Feifei Cao, Yu Ding, Luyang Wang, Xiaofei Zhu, Mengqi Zeng, Lei FuMulticolor luminescence is an attractive and emerging field for next-generation optoelectronic devices, including ultrathin displays, optical sensors, and wearable electronic devices. Currently, it is easy to achieve monochromatic emission, while the highly anticipated realization of multicolor luminescence in two-dimensional (2D) material is still blank. This is because the atomic thickness and structural ...
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Room-Temperature Magnetism in Two-Dimensional MnGa4-H Induced by Hydrogen InsertionAdvanced Materials (IF 32.086) Pub Date : 2023-03-10 ,DOI:10.1002/adma.202210828Nan Wei, Liangcheng He, Changwei Wu, Dabiao Lu, Ruohan Li, Haiwen Shi, Haihui Lan, Yao Wen, Jun He, Youwen Long, Xiao Wang, Mengqi Zeng, Lei FuTwo-dimensional (2D) room-temperature magnetic materials are of great importance in future spintronic devices while only very few have been reported. Herein, we exploit a plasma-enhanced chemical vapor deposition approach to construct the 2D room-temperature magnetic MnGa4-H single crystal with a thickness down to 2.2 nm. The employment of H2 plasma makes hydrogen atoms can be easily inserted into ...
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Efficacy of PBTZ169 and pretomanid against Mycobacterium avium, Mycobacterium abscessus, Mycobacterium chelonae, and Mycobacterium fortuitum in BALB/c mice modelsFrontiers in Cellular and Infection Microbiology (IF 6.073) Pub Date : 2023-03-07 ,DOI:10.3389/fcimb.2023.1115530Luyao Zheng, Xueting Qi, Weiyan Zhang, Hong Wang, Lei Fu, Bin Wang, Xi Chen, Xiaoyou Chen, Yu LuObjectives We aimed to evaluate the activity of PBTZ169 and pretomanid against non-tuberculous mycobacteriosis (NTM) in vitro and in vivo. Methods The minimum inhibitory concentrations (MICs) of 11 antibiotics, against slow-growing mycobacteria (SGMs) and rapid-growing mycobacteria (RGMs) were tested using the microplate alamarBlue assay. The in vivo activities of bedaquiline, clofazimine, moxifloxacin ...
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Analysis on displacement-based seismic design method of recycled aggregate concrete-filled square steel tube frame structuresStructural Concrete (IF 2.793) Pub Date : 2023-03-05 ,DOI:10.1002/suco.202200720Xianggang Zhang, Xuyan Liu, Songpeng Zhang, Junbo Wang, Lei Fu, Junna Yang, Yajun HuangRecycled aggregate concrete-filled square steel tube (S-RACFST) frame has the characteristics of high bearing capacity, good ductility, and superior seismic performance. To propose a displacement-based seismic design of S-RACFST frame, the validity of the design method was verified by a detailed calculation example. Based on the performance requirements, this design method divided the structural performance ...
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Clinical Validation of the sFlt-1:PlGF Ratio as a Biomarker for Preeclampsia Diagnosis in a High-Risk Obstetrics Unit.The Journal of Applied Laboratory Medicine Pub Date : 2023-03-03 ,DOI:10.1093/jalm/jfad003Jessica J Miller,Victoria Higgins,Nir Melamed,Michelle Hladunewich,Liyan Ma,Paul M Yip,Lei FuBACKGROUND Preeclampsia is a multisystem disorder defined by new onset of hypertension with proteinuria after 20 weeks gestation. In part due to dysregulation of pro-angiogenic factors (e.g., placental growth factor [PlGF]) and anti-angiogenic factors (e.g., soluble fms-like tyrosine kinase 1 [sFlt-1]), preeclampsia results in decreased placental perfusion. An increased sFlt-1:PlGF ratio is associated ...
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Complete Genome Sequences of Mycoplasma ovipneumoniae Strains 150 and 274, Isolated from Different Regions in Bosnia and Herzegovina.Microbiology Resource Announcements Pub Date : 2023-02-27 ,DOI:10.1128/mra.00011-23Huafang Hao,Zinka Maksimović,Lina Ma,Maid Rifatbegović,Shengli Chen,Xinmin Yan,Lei Fu,Yuefeng Chu
Mycoplasma ovipneumoniae is an important pathogen in sheep, goats, and wild ruminants. We sequenced M. ovipneumoniae strains 150 and 274 from Bosnia and Herzegovina. Strain 150 has a circular genome of 1,053,380 bp with 29.15% GC content while strain 274 has 1,081,404 bp with 28.82% GC content.
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Joint space-based optimal measurement configuration determination method for Stewart platform kinematics calibrationMeasurement (IF 5.131) Pub Date : 2023-02-24 ,DOI:10.1016/j.measurement.2023.112646Lei Fu, Zhihua Liu, Chenguang Cai, Meng Tao, Ming Yang, Haihui HuangThe accuracy problem is one of the most concerning problems for the industrial application of a Stewart platform, and kinematic calibration is a feasible way to solve it. Although various calibration methods have been proposed, there is still room for improvement in the accuracy and robustness of these studies. In this article, a dimensionless error model is investigated, and the kinematic parame-ter ...
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Effects of social support on suicide-related behaviors in patients with severe mental illness: A systematic review and meta-analysis.Journal of affective disorders Pub Date : 2023-02-21 ,DOI:10.1016/j.jad.2023.02.070Fei-Hong Hu,Dan-Yan Zhao,Xue-Lei Fu,Wan-Qing Zhang,Wen Tang,Shi-Qi Hu,Wang-Qin Shen,Hong-Lin ChenOBJECTIVE Patients with severe mental illness have a high risk of suicide and frequently living eliminated from mainstream society, but the effects of social support on suicide-related behaviors among this crowd is inconclusive. The present study aimed to explore such effects among patients with severe mental illness. METHODS We implemented a meta-analysis and a qualitative analysis of relevant studies ...
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Comparison of water-caprock and CO2-water-caprock geochemical reactivity in the Triassic Heshanggou Formation of Ordos BasinInternational Journal of Greenhouse Gas Control (IF 4.4) Pub Date : 2023-02-18 ,DOI:10.1016/j.ijggc.2023.103860Xin Ma, Yujie Diao, Lei Fu, Jing Yan, Guodong Yang, Chenglong Zhang, Siyu Liu, Hanchuan Dong, Ying YuThis study investigates the influence of geochemical reactions among CO2, water and key minerals on caprock sealing using laboratory experiments and numerical simulations, based on mudstone caprock of the Triassic Heshanggou Formation at the Shenhua CCS demonstration project in Ordos Basin. The results show that there is an obvious dissolution occurring in caprock after long-term water-rock interactions ...
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Demographics and Clinical Outcomes of Culture-Positive versus Culture-Negative Pyogenic Liver Abscess in an Asian PopulationInfection and Drug Resistance (IF 4.177) Pub Date : 2023-02-16 ,DOI:10.2147/idr.s395428Yao Liu, Jinqing Liu, Lei Fu, Chuan Jiang, Shifang Peng
Objective: Despite its high case-fatality risk, pyogenic liver abscess (PLA) lacks clear management guidelines in patients with negative microbial cultures. Our aim was to evaluate differences in clinical characteristics between patients with culture-negative liver abscess (CNLA) and those with culture-positive liver abscess (CPLA), and identify differences in the main causative pathogen. Methods:
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Metabolome-wide association study of four groups of persistent organic pollutants and abnormal blood lipidsEnvironment International (IF 13.352) Pub Date : 2023-02-13 ,DOI:10.1016/j.envint.2023.107817Yiran Chen, Jiayun Lv, Lei Fu, Yan Wu, Si Zhou, Shiwei Liu, Linjie Zheng, Wenru Feng, Lin ZhangEnvironmental exposure increases the risk of dyslipidemia, which affects human health. Research has shown that persistent organic pollutants (POPs), including per- and polyfluoroalkyl substances (PFASs), polychlorinated biphenyls, polybrominated diphenyl ethers, and phthalate metabolites, are associated with a higher risk of abnormal blood lipid levels in humans. However, the key molecules involved ...
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A multidimensional sensory evaluation model to investigate the (dis)comfort of body parts in a supine sitting position during a lunch breakHeliyon (IF 3.776) Pub Date : 2023-02-11 ,DOI:10.1016/j.heliyon.2023.e13624You-Lei Fu, Ruoqi Dai, Xiaoshun Xie, Wu Song
Employees who work long hours frequently complain of muscle fatigue caused by prolonged sitting. As a result, products that assist them when resting in a chair in a reclining position, in order to relieve fatigue and improve comfort are required. To ensure that the new product works as intended, a usability test based on prototyping must be developed. The research process was divided into three stages:
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Role of inflammatory lipid and fatty acid metabolic abnormalities induced by plastic additives exposure in childhood asthmaJournal of Environmental Sciences Pub Date : 2023-02-10 ,DOI:10.1016/j.jes.2023.02.005Zhiyu Chen, Fang Li, Lei Fu, Yu Xia, Ying Luo, Ang Guo, Xiaona Zhu, Huifang Zhong, Qian LuoLipid metabolism play an essential role in occurrence and development of asthma, and it can be disturbed by phthalate esters (PAEs) and organophosphate flame retardants (OPFRs). As a chronic inflammatory respiratory disease, the occurrence risk of childhood asthma is increased by PAEs and OPFRs exposure, but it remains not entirely clear how PAEs and OPFRs contribute the onset and progress of the disease ...
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Identification of AKR1B10 as a key gene in primary biliary cholangitis by integrated bioinformatics analysis and experimental validationFrontiers in Molecular Biosciences (IF 6.113) Pub Date : 2023-02-09 ,DOI:10.3389/fmolb.2023.1124956Huiwen Wang, Jian Zhang, Jinqing Liu, Yongfang Jiang, Lei Fu, Shifang Peng
Background: Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease that eventually progresses to cirrhosis and hepatocellular carcinoma (HCC) in the absence of proper treatment. However, Gene expression and molecular mechanisms involved in the pathogenesis of PBC have not been completely elucidated.Methods: Microarray expression profiling dataset GSE61260 was downloaded from the Gene
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Optical solitons in birefringent fibers with the generalized coupled space–time fractional non-linear Schrödinger equationsFrontiers in Physics (IF 3.718) Pub Date : 2023-02-06 ,DOI:10.3389/fphy.2023.1108505Lei Fu, Jingjing Li, Hongwei Yang, Huanhe Dong, Xiaofeng Han
The nonlinear Schrödinger (NLS) equation is an ideal model for describing optical soliton transmission. This paper first introduces an integer-order generalized coupled NLS equation describing optical solitons in birefringence fibers. Secondly, the semi-inverse and fractional variational method is used to extend the integer‐order model to the space–time fractional order. Moreover, various nonlinear
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Observer-based event-triggered non-PDC control for networked T-S fuzzy systems under actuator failures and aperiodic DoS attacksInformation Sciences (IF 8.233) Pub Date : 2023-02-04 ,DOI:10.1016/j.ins.2023.01.140Siyi Guo, Yanan Xu, Yuechao Ma, Lei FuThis article addresses the observer-based event-triggered non-parallel distribution compensation (PDC) H∞ control issue for networked T-S fuzzy systems (TSFSs) under actuator failures and aperiodic denial-of-service (DoS) attacks. In order to alleviate the interference of network transmission, a fuzzy observer following the asynchronous premise variables as the system is constructed, and we design ...
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Regional Spectral Characteristics Derived Using the Generalized Inversion Technique and Applications to Stochastic Simulation of the 2021 Mw 6.1 Yangbi EarthquakeBulletin of the Seismological Society of America (IF 3.14) Pub Date : 2023-02-01 ,DOI:10.1785/0120220088Lei Fu, Su Chen, Jiangyi Li, Libao Zhang, Junju Xie, Xiaojun LiIn this study, 334 accelerograms of 42 small‐to‐moderate earthquakes recorded at 36 strong‐motion stations were used to investigate the ground‐motion characteristics of the southwestern margin of the Sichuan–Yunnan rhombic block (SWM‐SYRB), one of the most active seismic regions in China. The high‐frequency attenuation parameter was estimated using the spectral decay method, and the site component ...
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Chemical Potential-Modulated Ultrahigh-Phase-Purity Growth of Ultrathin Transition-Metal Boride Single CrystalsJournal of the American Chemical Society (IF 16.383) Pub Date : 2023-01-27 ,DOI:10.1021/jacs.2c11139Jingjing Si, Jinqiu Yu, Haihui Lan, Lixin Niu, Jingrui Luo, Yantao Yu, Linyang Li, Yu Ding, Mengqi Zeng, Lei FuTwo-dimensional (2D) transition-metal borides (TMBs) are especially expected to exhibit excellent performance in various fields among electricity, superconductivity, magnetism, mechanics, biotechnology, battery, and catalysis. However, the synthesis of ultrathin TMB single crystals with ultrahigh phase purity was deemed extremely challenging and has not been realized till date. That is because TMBs ...
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Multi-omics profiling and digital image analysis reveal the potential prognostic and immunotherapeutic properties of CD93 in stomach adenocarcinomaFrontiers in Immunology (IF 8.786) Pub Date : 2023-01-25 ,DOI:10.3389/fimmu.2023.984816Baokang Wu, Lei Fu, Xingqi Guo, Huixin Hu, Yang Li, Yu Shi, Yizhou Zhang, Shukun Han, Chao Lv, Yu Tian
BackgroundRecent evidence highlights the fact that immunotherapy has significantly improved patient outcomes. CD93, as a type I transmembrane glycoprotein, was correlated with tumor-associated angiogenesis; however, how CD93 correlates with immunotherapy in stomach adenocarcinoma (STAD) remains unclear.MethodsTCGA, GTEx, GEO, TIMER2.0, HPA, TISIDB, TCIA, cBioPortal, LinkedOmics, and ImmuCellAI public
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LINC01004-SPI1 axis-activated SIGLEC9 in tumor-associated macrophages induces radioresistance and the formation of immunosuppressive tumor microenvironment in esophageal squamous cell carcinomaCancer Immunology, Immunotherapy (IF 6.63) Pub Date : 2023-01-23 ,DOI:10.1007/s00262-022-03364-5Fen Zhao, Hui Tian, Yungang Wang, Jianbo Zhang, Fang Liu, Lei Fu
Radioresistance and immunosuppression remain the major obstacles in the anti-cancer treatments. This work studies the functions of sialic acid binding Ig like lectin 9 (SIGLEC9) and its related molecules in radioresistance and immunosuppression in esophageal squamous cell carcinoma (ESCC). The single-cell analysis showed that SIGLEC9 was mainly expressed on tumor-associated macrophages (TAMs). Monocytes-derived
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Guiding Drug Repositioning for Cancers Based on Drug Similarity Networks.International Journal of Molecular Sciences (IF 6.208) Pub Date : 2023-01-23 ,DOI:10.3390/ijms24032244Shimei Qin,Wan Li,Hongzheng Yu,Manyi Xu,Chao Li,Lei Fu,Shibin Sun,Yuehan He,Junjie Lv,Weiming He,Lina Chen
Drug repositioning aims to discover novel clinical benefits of existing drugs, is an effective way to develop drugs for complex diseases such as cancer and may facilitate the process of traditional drug development. Meanwhile, network-based computational biology approaches, which allow the integration of information from different aspects to understand the relationships between biomolecules, has been
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Hydrodynamic Performance of A Dual-Floater Integrated System Combining Hybrid WECs and Floating BreakwatersChina Ocean Engineering (IF 0.835) Pub Date : 2023-01-19 ,DOI:10.1007/s13344-022-0085-9Lei Fu, Yong ChengThe high investment and low return of wave energy converters (WECs) seriously hamper their large-scale commercial application. The integration of WECs and floating breakwaters is conducive to enhance the competitiveness of wave energy conversion. The objective of this paper is to investigate the hydrodynamic performance of a WEC-breakwater integrated system combining an upstream oscillating water column ...
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MiR-526b targets lncRNA SLC16A1-AS1 to suppress cell proliferation in triple-negative breast cancerJournal of Biochemical and Molecular Toxicology (IF 3.568) Pub Date : 2023-01-18 ,DOI:10.1002/jbt.23247Xingjuan Zhao, Lei Fu, Liqin Zhai, Xuan Yang, Runfang GaoThe present study investigated the potential interaction between miR-526b and lncRNA SLC16A1-AS1 in triple-negative breast cancer (TNBC). Expression of miR-526b and SLC16A1-AS1 in TNBC tumor tissues and paired nontumor tissues from 60 TNBC patients was detected by real-time polymerase chain reaction (RT-qPCR). The interaction between miR-526b and SLC16A1-AS1 was evaluated with overexpression experiments ...
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Biomarkers of hepatocellular synthesis in patients with decompensated cirrhosisHepatology International (IF 9.029) Pub Date : 2023-01-18 ,DOI:10.1007/s12072-022-10473-xBerivan Gurbuz, Nurdan Guldiken, Philipp Reuken, Lei Fu, Katharina Remih, Christian Preisinger, Radan Brůha, Martin Leníček, Jaromír Petrtýl, Johanna Reissing, Mahmoud Aly, Malin Fromme, Biaohuan Zhou, Isabel Karkossa, Kristin Schubert, Martin von Bergen, Andreas Stallmach, Tony Bruns, Pavel Strnad
Background and aim Since hepatocytes produce majority of serum proteins, patients with cirrhosis display substantial alterations in the serum proteome. The aim of the current study was to characterize these changes and to study the prognostic utility of hepatocellular proteins available in routine clinical testing. Methods Sera from 29 healthy controls and 43 patients with cirrhosis were subjected
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Automated deep-learning system in the assessment of MRI-visible prostate cancer: comparison of advanced zoomed diffusion-weighted imaging and conventional techniqueCancer Imaging (IF 5.605) Pub Date : 2023-01-17 ,DOI:10.1186/s40644-023-00527-0Hu, Lei, Fu, Caixia, Song, Xinyang, Grimm, Robert, von Busch, Heinrich, Benkert, Thomas, Kamen, Ali, Lou, Bin, Huisman, Henkjan, Tong, Angela, Penzkofer, Tobias, Choi, Moon Hyung, Shabunin, Ivan, Winkel, David, Xing, Pengyi, Szolar, Dieter, Coakley, Fergus, Shea, Steven, Szurowska, Edyta, Guo, Jing-yi, Li, Liang, Li, Yue-hua, Zhao, Jun-gong
Deep-learning-based computer-aided diagnosis (DL-CAD) systems using MRI for prostate cancer (PCa) detection have demonstrated good performance. Nevertheless, DL-CAD systems are vulnerable to high heterogeneities in DWI, which can interfere with DL-CAD assessments and impair performance. This study aims to compare PCa detection of DL-CAD between zoomed-field-of-view echo-planar DWI (z-DWI) and full-field-of-view
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Passive Fault-Tolerant Control for NCSs Using Event-Triggered ApproachIEEE Access (IF 3.476) Pub Date : 2023-01-09 ,DOI:10.1109/access.2023.3235350Lei Fu, Jiachang Shi, Fei Li
In this paper, the passive event-triggered control problem for networked control systems with actuator faults is of concern. A sufficient condition is proposed by a Lyapunov-Krasovskii functional, under which such type continuous-time Networked control systems with actuator faults are asymptotically stable and passive. The designing method of controller is developed by using Wirtinger inequality and
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Efficacy of Replacing Linezolid with OTB-658 in Anti-Tuberculosis Regimens in Murine ModelsAntimicrobial Agents and Chemotherapy (IF 5.938) Pub Date : 2023-01-09 ,DOI:10.1128/aac.01399-22Haiting Liu, Hui Zhu, Lei Fu, Weiyan Zhang, Xi Chen, Bin Wang, Shaochen Guo, Yangming Ding, Ning Wang, Dongshuo Li, Yu Lu aDepartment of Pharmacology, Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, People’s Republic of ChinaAntimicrobial Agents and Chemotherapy, Ahead of Print. ...
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Structure modulation of two-dimensional transition metal chalcogenides: recent advances in methodology, mechanism and applicationsChemical Society Reviews (IF 60.615) Pub Date : 2023-01-05 ,DOI:10.1039/d1cs01016fYao Xiao, Chengyi Xiong, Miao-Miao Chen, Shengfu Wang, Lei Fu, Xiuhua ZhangTogether with the development of two-dimensional (2D) materials, transition metal dichalcogenides (TMDs) have become one of the most popular series of model materials for fundamental sciences and practical applications. Due to the ever-growing requirements of customization and multi-function, dozens of modulated structures have been introduced in TMDs. In this review, we present a systematic and comprehensive ...
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