- 作 者: ( "junmei chen" OR "jun-mei chen" )
-
A double serial concatenated code using CRC-aided error correction for highly reliable communicationComputer Networks (IF 5.493) Pub Date : 2022-08-06 ,DOI:10.1016/j.comnet.2022.109260Junmei Chen, Hao Chen, Zongpeng LiHighly Reliable Communication (HRC) is an emerging paradigm for meeting the quality of service requirements of new applications such as intelligent vehicle networking and industrial Internet. HRC brings challenges to channel coding and multiple access. Various channel coding techniques have been proposed to improve reliability, but often suffer from limited reliability and high decoding complexity ...
-
Reduced Proteolytic Cleavage of von Willebrand Factor Leads to Aortic Valve Stenosis and Load-Dependent Ventricular RemodelingJACC: Basic to Translational Science (IF 9.531) Pub Date : 2022-06-29 ,DOI:10.1016/j.jacbts.2022.02.021Koya Ozawa, Matthew A. Muller, Oleg Varlamov, Matthew W. Hagen, William Packwood, Terry K. Morgan, Aris Xie, Claudia S. López, Dominic Chung, Junmei Chen, José A. López, Jonathan R. Lindner
We hypothesized that excess endothelial-associated von Willebrand factor (vWF) and secondary platelet adhesion contribute to aortic valve stenosis (AS). We studied hyperlipidemic mice lacking ADAMTS13 (LDLR−/−AD13−/−), which cleaves endothelial-associated vWF multimers. On echocardiography and molecular imaging, LDLR−/−AD13−/− compared with control strains had increased aortic endothelial vWF and platelet
...
-
Microstructural evolution and mechanical behavior of additive manufactured 17-4 PH steel with a periodic layer structureMaterials Science and Engineering: A (IF 6.044) Pub Date : 2022-06-28 ,DOI:10.1016/j.msea.2022.143527Zhiyuan Yu, Ze Chai, Chun Yu, Junmei Chen, Jijin Xu, Hao LuMaterials produced by additive manufacturing experience a unique thermal history, and particularly, proper laser remelting (LR) can introduce additional austenite in the laser direct metal deposited 17-4 PH steels. Taking advantage of the LR process and subsequent aging, we designed periodic-layered 17-4 PH steels with different austenite distributions in this study. The evolution of microstructural ...
-
A numerical model-based deposition strategy for heat input regulation during plasma arc-based additive manufacturingAdditive Manufacturing (IF 11.632) Pub Date : 2022-06-18 ,DOI:10.1016/j.addma.2022.102986Yi Zheng, Zhiyuan Yu, Jingren Xie, Junmei Chen, Chun Yu, Jijin Xu, Hao LuHeat accumulation in metal additive manufacturing (AM) processes leads to the unstable molten pool size, nonuniform track morphology, excessive dilution, and even structural collapse. Therefore, appropriate heat input management to alleviate heat accumulation is critical for metal AM processes. In order to mitigate heat accumulation and achieve better geometric accuracy, this work develops an innovative ...
-
Comprehensive molecular evaluation of the histone methyltransferase gene family and their important roles in two-line hybrid wheatBMC Plant Biology (IF 5.26) Pub Date : 2022-06-13 ,DOI:10.1186/s12870-022-03639-0Sun, Renwei, Gong, Jie, Liu, Yongjie, Chen, Zhaobo, Zhang, Fengting, Gao, Jiangang, Cao, Junmei, Chen, Xianchao, Zhang, Shengquan, Zhao, Changping, Gao, Shiqing
Histone methylation usually plays important roles in plant development through post-translational regulation and may provide a new visual field for heterosis. The histone methyltransferase gene family has been identified in various plants, but its members and functions in hybrid wheat related in heterosis is poorly studied. In this study, 175 histone methyltransferase (HMT) genes were identified in
...
-
Promoting oxygen reduction via coordination environment modulation through secondary metal-atom incorporationJournal of Materials Chemistry A (IF 14.511) Pub Date : 2022-05-25 ,DOI:10.1039/d2ta01962kHaozhou Yang, Tianyu Zhang, Xiao Chi, Xiaojiang Yu, Junmei Chen, Jiayi Chen, Chunfeng Li, Shengdong Tan, Qian He, Xun Wang, Lei WangFe-based single-atom catalysts (SACs) have been recognized as attractive candidates for the oxygen reduction reaction (ORR). However, several limitations such as unsatisfactory intrinsic activity and poor stability hinder their practical applications, motivating further optimization of Fe-SACs which requires precise control of their composition and coordination environment. Herein, we establish a facile ...
-
Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP.Blood (IF 25.476) Pub Date : 2022-04-21 ,DOI:10.1182/blood.2021012896Bojing Shao,Christopher Hoover,Huiping Shi,Yuji Kondo,Robert H Lee,Junmei Chen,Xindi Shan,Jianhua Song,J Michael McDaniel,Meixiang Zhou,Samuel McGee,Karen Vanhoorelbeke,Wolfgang Bergmeier,José A López,James N George,Lijun Xia
Microvascular thrombosis in patients with thrombotic thrombocytopenic purpura (TTP) is initiated by GPIbα-mediated platelet binding to von Willebrand factor (VWF). Binding of VWF to GPIbα causes activation of the platelet surface integrin αIIbβ3. However, the mechanism of GPIbα-initiated activation of αIIbβ3 and its clinical importance for microvascular thrombosis remain elusive. Deletion of platelet
...
-
Endothelial-derived von Willebrand factor accelerates fibrin clotting within engineered microvessels.Journal of Thrombosis and Haemostasis (IF 16.036) Pub Date : 2022-04-11 ,DOI:10.1111/jth.15714Samuel G Rayner,Zackary Scholl,Christian J Mandrycky,Junmei Chen,Karina N LaValley,Peter J Leary,William A Altemeier,W Conrad Liles,Dominic W Chung,José A López,Hongxia Fu,Ying ZhengBACKGROUND Von Willebrand factor (VWF) is classically associated with primary hemostasis and platelet-rich arterial thromboses, but recently has also been implicated in fibrin clotting and venous thrombosis. Direct interaction between fibrin and VWF may mediate these processes, although prior reports are conflicting. OBJECTIVES We combined two complementary platforms to characterize VWF-fibrin(ogen) ...
-
Endothelial-derived von Willebrand factor accelerates fibrin clotting within engineered microvesselsJournal of Thrombosis and Haemostasis (IF 16.036) Pub Date : 2022-03-28 ,DOI:10.1111/jth.15714Samuel G. Rayner, Zackary Scholl, Christian J. Mandrycky, Junmei Chen, Karina N. LaValley, Peter J. Leary, William A. Altemeier, W. Conrad Liles, Dominic W. Chung, José A. López, Hongxia Fu, Ying ZhengVon Willebrand factor (VWF) is classically associated with primary hemostasis and platelet-rich arterial thromboses, but recently has also been implicated in fibrin clotting and venous thrombosis. Direct interaction between fibrin and VWF may mediate these processes, although prior reports are conflicting. ...
-
A comprehensive analysis of ultrasonic pulse current reducing hot cracking in Inconel 718 weldsMaterials Characterization (IF 4.537) Pub Date : 2022-03-14 ,DOI:10.1016/j.matchar.2022.111840Yajie Wang, Xiaoqiang Zhang, Daqing Wang, Jieshi Chen, Chun Yu, Junmei Chen, Jijin Xu, Ping Zhu, Hao LuA novel self-induced ultrasonic tungsten inert gas (U-TIG) welding has been successfully applied to weld the Inconel 718 sheet with thickness of 2 mm to reduce hot cracking. The welding arc, weld formation, microstructure and micro-hardness distribution between TIG and U-TIG welding were analyzed systematically. The relationship between micro-hardness and characteristics of grain size, grain orientation ...
-
Phenotypic analysis of erythrocytes in sickle cell disease using imaging flow cytometryCytometry Part A (IF 4.714) Pub Date : 2022-01-31 ,DOI:10.1002/cyto.a.24536Tahsin Özpolat, Tim C. Chang, Xiaoping Wu, Alexander E. St. John, Barbara A. Konkle, Junmei Chen, José A. LópezThe morphology and other phenotypic characteristics of erythrocytes in sickle cell disease (SCD) have been analyzed for decades in patient evaluation. This involves a variety of techniques, including microscopic analysis of stained blood films, flow cytometry, and cell counting. Here, we analyzed SCD blood using imaging flow cytometry (IFC), a technology that combines flow cytometry and microscopy ...
-
Ferroptosis Markers Predict the Survival, Immune Infiltration, and Ibrutinib Resistance of Diffuse Large B cell LymphomaInflammation (IF 4.657) Pub Date : 2022-01-22 ,DOI:10.1007/s10753-021-01609-6Weng, Junmei, Chen, Lian, Liu, Huicheng, Yang, Xiang-Ping, Huang, LiuDiffuse large B cell lymphoma (DLBCL) is the most common hematological malignancy in adults. Ferroptosis is an iron-dependent programmed cell death caused by lipid peroxidation. However, the potential functions of ferroptosis in the DLBCL prognosis, immune infiltration, and drug resistance remain unknown. Data of DLBCL patients were downloaded from public GEO databases and TCGA cohort. R software was ...
-
Characterization of histone deacetylases and their roles in response to abiotic and PAMPs stresses in Sorghum bicolorBMC Genomics (IF 4.547) Pub Date : 2022-01-06 ,DOI:10.1186/s12864-021-08229-2Du, Qiaoli, Fang, Yuanpeng, Jiang, Junmei, Chen, Meiqing, Fu, Xiaodong, Yang, Zaifu, Luo, Liting, Wu, Qijiao, Yang, Qian, Wang, Lujie, Qu, Zhiguang, Li, Xiangyang, Xie, Xin
Histone deacetylases (HDACs) play an important role in the regulation of gene expression, which is indispensable in plant growth, development, and responses to environmental stresses. In Arabidopsis and rice, the molecular functions of HDACs have been well-described. However, systematic analysis of the HDAC gene family and gene expression in response to biotic and abiotic stresses has not been reported
...
-
Elevated plasma von Willebrand factor levels are associated with subsequent ischemic stroke in persons with treated HIV infectionOpen Forum Infectious Diseases (IF 4.423) Pub Date : 2021-10-21 ,DOI:10.1093/ofid/ofab521Susan M Graham, Robin M Nance, Junmei Chen, Jennie Le, Dominic W Chung, Mark M Wurfel, David L Tirschwell, Joseph R Zunt, Christina M Marra, Emily L Ho, Andrew Huffer, Felicia C Chow, Jeffrey N Martin, Alice S Ryan, Heidi M Crane, José A López, W Conrad Liles
Background We assessed whether key biomarkers of endothelial activation and hemostasis/thrombosis were elevated in individuals receiving effective antiretroviral therapy (ART) in the year before ischemic stroke. Methods We conducted a case-control study nested in the CNICS cohort, comparing 42 adjudicated cases with ischemic stroke to 83 controls matched for ART regimen. Angiopoietin-1, angiopoietin-2
...
-
Screening and verification of CYP3A4 inhibitors from Bushen-Yizhi formula to enhance the bioavailability of osthole in rat plasmaJournal of Ethnopharmacology (IF 5.195) Pub Date : 2021-09-14 ,DOI:10.1016/j.jep.2021.114643Jin-man Liu, Jun-mei Chen, Ming-jun Lin, Fan-chang Wu, Cui-ru Ma, Xue Zuo, Wen-qian Yu, Ming-jun Huang, Jian-song Fang, Wei-rong Li, Qi Wang, Yong LiangEthnopharmacological relevance With the features of multiple-components and targets as well as multifunction, traditional Chinese medicine (TCM) has been widely used in the prevention and treatment of various diseases for a long time. During the application of TCM, the researches about bioavailability enhancement of the bioactive constituents in formula are flourishing. Bushen-Yizhi formula (BSYZ) ...
-
Heterogeneous mechanical properties along the building direction in direct laser deposited 17-4 PH steelMaterials Science and Engineering: A (IF 6.044) Pub Date : 2021-08-19 ,DOI:10.1016/j.msea.2021.141936Chuanfeng Wu, Junmei Chen, Zhiyuan Yu, Chun Yu, Jijin Xu, Hao LuShanghai Key Laboratory of Materials Laser Processing and Modification, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, ChinaThe present work thoroughly investigated the heterogeneous mechanical properties along the building direction in a direct laser deposited 17-4 PH part by tensile tests. From top to bottom (1# - 5#) in the as-built cuboid, the yield strength enhanced from ~729 MPa to ~1050 MPa, while the elongation decreased from ~4.69% to ~1.50%. The microstructure of samples was composed of main martensite, reversed ...
-
Achieving high strength and ductility in 17-4 PH steel with a periodic layer structure by laser direct metal depositing and agingMaterials Science and Engineering: A (IF 6.044) Pub Date : 2021-07-24 ,DOI:10.1016/j.msea.2021.141787Zhiyuan Yu, Ze Chai, Jijin Xu, Jieshi Chen, Junmei Chen, Chun Yu, Hao LuA periodic layer (PL) structure characterized with interval distribution of austenite for 17-4 PH steel is achieved by the laser direct metal deposition and aging. The synergism of strain partitioning hardening and austenitic transformation-induced plasticity contributes crucially to the excellent strength-ductility combination in the PL structured 17-4 PH steel. ...
-
Insights into oral bioavailability enhancement of therapeutic herbal constituents by cytochrome P450 3A inhibitionDrug Metabolism Reviews (IF 6.984) Pub Date : 2021-04-27 ,DOI:10.1080/03602532.2021.1917598Junmei Chen, Jinman Liu, Yueyue Huang, Ruoyu Li, Cuiru Ma, Beiping Zhang, Fanchang Wu, Wenqian Yu, Xue Zuo, Yong Liang, Qi WangAbstract Herbal plants typically have complex compositions and diverse mechanisms. Among them, bioactive constituents with relatively high exposure in vivo are likely to exhibit therapeutic efficacy. On the other hand, their bioavailability may be influenced by the synergistic effects of different bioactive components. Cytochrome P450 3A (CYP3A) is one of the most abundant CYP enzymes, responsible ...
-
Arterial Platelet Adhesion in Atherosclerosis‐Prone Arteries of Obese, Insulin‐Resistant Nonhuman PrimatesJournal of the American Heart Association (IF 6.106) Pub Date : 2021-04-21 ,DOI:10.1161/jaha.120.019413Eran Brown, Koya Ozawa, Federico Moccetti, Amanda Vinson, James Hodovan, The Anh Nguyen, Lindsay Bader, José A. López, Paul Kievit, Gray D. Shaw, Dominic W. Chung, Warren Osborn, Xiaoyun Fu, Junmei Chen, Jonathan R. Lindner
BackgroundPlatelet–endothelial interactions are thought to contribute to early atherogenesis. These interactions are potentiated by oxidative stress. We used in vivo molecular imaging to test the hypothesis that platelet–endothelial interactions occur at early stages of plaque development in obese, insulin‐resistant nonhuman primates, and are suppressed by NADPH‐oxidase‐2 inhibition.Methods and ResultsSix
...
-
Plasma proteomic profile associated with platelet dysfunction after traumaJournal of Thrombosis and Haemostasis (IF 16.036) Pub Date : 2021-03-28 ,DOI:10.1111/jth.15316Alexander St. John, Yi Wang, Junmei Chen, Warren Osborn, Xu Wang, Esther Lim, Dominic Chung, Susan Stern, Nathan White, Xiaoyun Fu, José LópezCoagulopathic bleeding is a major cause of mortality after trauma, and platelet dysfunction contributes to this problem. The causes of platelet dysfunction are relatively unknown, but a great deal can be learned from the plasma environment about the possible pathways involved. ...
-
Simultaneously enhanced strength and ductility of TIG welds in Inconel 718 super-alloy via ultrasonic pulse currentMaterials Science and Engineering: A (IF 6.044) Pub Date : 2021-02-05 ,DOI:10.1016/j.msea.2021.140894Yajie Wang, Weihua Liu, Daqing Wang, Chun Yu, Jijin Xu, Hao Lu, Junmei ChenThis paper presents a novel self-induced ultrasonic arc welding (U-TIG) with high-efficient, which improves tensile strength and ductility of TIG welds in Inconel 718 super-alloy simultaneously. The effects of ultrasonic frequencies on arc shape, weld forming and weld penetration characteristics were systematically studied by high-speed camera and optical microscope. The characteristics of grains and ...
-
Ductility Anisotropy Induced by Ferrite in Direct Laser Deposited 17-4 PH Steel: Combined Microstructure and Dislocation Density SimulationActa Metallurgica Sinica-English Letters (IF 3.024) Pub Date : 2021-01-02 ,DOI:10.1007/s40195-020-01172-3Chuanfeng Wu, Junmei Chen, Zhiyuan Yu, Hao Lu, Chun Yu, Jijin XuThe anisotropic ductility of a direct laser deposited 17-4 PH cubic part was investigated. Anisotropic elongations in the specimens from varied surfaces of the part were obtained: ~ 6.2%, ~ 1.5%, and ~ 4.5% in XY, YZ, and XZ samples, respectively. Furthermore, various orientations of ferrite were found in different specimens, taking the loading direction as reference. A finite element analysis depending ...
-
Ductility Anisotropy Induced by Ferrite in Direct Laser Deposited 17-4 PH Steel: Combined Microstructure and Dislocation Density SimulationActa Metallurgica Sinica (English Letters) Pub Date : 2021-01-02 ,DOI:10.1007/s40195-020-01172-3Chuanfeng Wu, Junmei Chen, Zhiyuan Yu, Hao Lu, Chun Yu, Jijin XuThe anisotropic ductility of a direct laser deposited 17-4 PH cubic part was investigated. Anisotropic elongations in the specimens from varied surfaces of the part were obtained: ~ 6.2%, ~ 1.5%, and ~ 4.5% in XY, YZ, and XZ samples, respectively. Furthermore, various orientations of ferrite were found in different specimens, taking the loading direction as reference. A finite element analysis depending ...
-
Prognostic Biomarkers for Thrombotic Microangiopathy after Acute Graft-versus-Host Disease: A Nested Case-Control Study.Transplantation and Cellular Therapy Pub Date : 2020-12-16 ,DOI:10.1016/j.jtct.2020.12.010Ang Li,Pavan K Bhatraju,Junmei Chen,Dominic W Chung,Tristan Hilton,Katie Houck,Emily Pao,Noel S Weiss,Stephanie J Lee,Chris Davis,Martin J Schmidt,Jose A Lopez,W Conrad Liles,Jing-Fei Dong,Sangeeta R Hingorani
Transplantation-associated thrombotic microangiopathy (TA-TMA) is a complication of allogeneic hematopoietic cell transplantation (HCT) that often occurs following the development of acute graft-versus-host disease (aGVHD). In this study, we aimed to identify early TMA biomarkers among patients with aGVHD. We performed a nested-case-control study from a prospective cohort of allogeneic HCT recipients
...
-
Human Platelets Stored at Room Temperature Demonstrate Diminished Resistance to Oxidative Stress Compared to Those Stored at 4°CBlood (IF 25.476) Pub Date : 2020-11-05 ,DOI:10.1182/blood-2020-143190Xiaoyun Fu,Warren Osborn,Yu Shen,Yi Wang,Jeffrey Miles,Lydia Fang,Barbara Osborne,Junmei Chen,José A. López,Moritz Stolla
Background: Current blood banking practices dictate that platelets can only be stored at room temperature (RT) for up to seven days because of functional decline and risk of bacterial overgrowth. A lower storage temperature has the potential to slow platelet metabolism and reduce oxidative damage during storage. In the current study, we quantified by mass spectrometry small molecule thiols and disulfides
...
-
Targeted Proteomics Reveals That the Dominant Mechanism of Gpibα Loss during Platelet Storage Depends on Temperature of StorageBlood (IF 25.476) Pub Date : 2020-11-05 ,DOI:10.1182/blood-2020-143077Moritz Stolla,Yi Wang,Jeffrey Miles,Barbara Osborne,Yu Shen,Lydia Fang,Shawn Lawrence Bailey,Warren Osborn,Junmei Chen,Jose A. Lopez,Xiaoyun Fu
Background: Platelet transfusion is a potentially lifesaving procedure, used for both prophylactic and therapeutic indications. Platelets can be stored at room temperature (RT) for up to 7 days in air-permeable bags. Platelet function diminishes during storage, a phenomenon known as the storage lesion. We and others have shown that platelets can be stored for extended periods of time at 4°C and still
...
-
Plasma Proteomic Profile Associated with Platelet Dysfunction after TraumaBlood (IF 25.476) Pub Date : 2020-11-05 ,DOI:10.1182/blood-2020-141361Alexander E St. John,Yi Wang,Junmei Chen,Warren Osborn,Xu Wang,Esther Lim,Dominic W. Chung,Susan Stern,Nathan White,Xiaoyun Fu,Jose A. Lopez
Background. Coagulopathic bleeding is a major cause of mortality after trauma, and platelet dysfunction contributes to this problem. The causes of platelet dysfunction are unknown, but a great deal can be learned from the plasma environment after injury, which may directly alter platelet function. Studying the changes in plasma using untargeted proteomics would provide unbiased insight into the presence
...
-
Effect of laser remelting processing on microstructure and mechanical properties of 17-4 PH stainless steel during laser direct metal depositionJournal of Materials Processing Technology (IF 6.162) Pub Date : 2020-10-01 ,DOI:10.1016/j.jmatprotec.2020.116738Zhiyuan Yu, Yi Zheng, Junmei Chen, Chuanfeng Wu, Jijin Xu, Hao Lu, Chun YuAbstract Laser direct metal deposition (DMD) is an efficient and flexible additive manufacturing technique which has broad application prospects, but it is also limited due to defects and mechanical anisotropy. Laser remelting (LR) is a process that after each layer is deposited, re-scan the deposition layer with the same slice data but without powder deliver, and it is often used during selective ...
-
Research status and future perspectives on ultrasonic arc welding techniqueJournal of Manufacturing Processes (IF 5.684) Pub Date : 2020-09-14 ,DOI:10.1016/j.jmapro.2020.09.005Yajie Wang, Chun Yu, Hao Lu, Junmei ChenIn recent years, ultrasonic arc welding technology, a novel and promising welding process, has been widely applied in the welding of steel, aluminum alloy, titanium alloy, nickel base alloy and composite materials to improve the welding efficiency and quality of the welded joints. This paper reviews the research status of ultrasonic arc welding technology, systematically classifies and summarizes the ...
-
Comparison of the Stress Corrosion Cracking Behaviour of AISI 304 Pipes Welded by TIG and LBWActa Metallurgica Sinica-English Letters (IF 3.024) Pub Date : 2020-09-01 ,DOI:10.1007/s40195-020-01126-9Ji-Jin Xu, Shuai Wang, Ze Chai, Chun Yu, Jun-Mei Chen, Hao LuThe stress corrosion cracking (SCC) behaviour of AISI 304 pipe girth welds which were welded by a single-pass laser beam welding (LBW) and a multi-pass tungsten inert gas welding (TIG), respectively, was studied by the slow strain rate tests combined with the electrochemical corrosion tests. The results show that fracture of both the TIG joint and LBW joint occurs in the heat-affected zone (HAZ). According ...
高级搜索
我的搜索条件
京公网安备 11010802027423号