- 作 者: "lin cheng"
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Sphingosine 1-phosphate receptor 1 regulates blood-brain barrier permeability in epileptic mice.Neural Regeneration Research (IF 6.058) Pub Date : 2023-08-01 ,DOI:10.4103/1673-5374.360263Li-Xiang Yang,Yuan-Yuan Yao,Jiu-Rong Yang,Hui-Lin Cheng,Xin-Jian Zhu,Zhi-Jun ZhangDestruction of the blood-brain barrier is a critical component of epilepsy pathology. Several studies have demonstrated that sphingosine 1-phosphate receptor 1 contributes to the modulation of vascular integrity. However, its effect on blood-brain barrier permeability in epileptic mice remains unclear. In this study, we prepared pilocarpine-induced status epilepticus models and pentylenetetrazol-induced ...
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Clinical Outcome and Safety of Lumboperitoneal Shunt in the Treatment of Non-Obstructive HydrocephalusClinical Interventions in Aging (IF 3.829) Pub Date : 2023-03-23 ,DOI:10.2147/cia.s401116Ning-Ping Foo, Yang Chien Tun, Che Chao Chang, Hung-Lin Lin, Cheng-Hsin Cheng, Hao-Yu ChuangObjective: This study aimed to evaluate the functional outcomes of lumboperitoneal (LP) shunt for the treatment of non-obstructive hydrocephalus. Methods: We retrospectively studied the clinical surgical results of 172 adult patients with hydrocephalus who underwent LP shunt surgery between June 2014 and June 2019. Data regarding the following were collected: pre- and postoperative symptom status, ...
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Efficient numerical approach to high-fidelity phase-modulated gates in long chains of trapped ionsPhysical Review E (IF 2.707) Pub Date : 2023-03-22 ,DOI:10.1103/physreve.107.035304Sheng-Chen Liu, Lin Cheng, Gui-Zhong Yao, Ying-Xiang Wang, Liang-You PengAlmost every quantum circuit is built with two-qubit gates in the current stage, which are crucial to the quantum computing in any platform. The entangling gates based on Mølmer-Sørensen schemes are widely exploited in the trapped-ion system, with the utilization of the collective motional modes of ions and two laser-controlled internal states, which are served as qubits. The key to realize high-fidelity ...
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High-Performance Aqueous Zinc-Ion Hybrid Capacitors based on 3D Printed Metal-Organic Framework CathodesChemical Engineering Journal (IF 16.744) Pub Date : 2023-03-21 ,DOI:10.1016/j.cej.2023.142544Noelle R. Catarineu, Dun Lin, Cheng Zhu, Diego I. Oyarzun, Yat LiThe zinc-ion hybrid capacitor is a promising energy storage device, but current overall capacity is limited by the capacitance of the carbon cathode. We produced a hierarchically porous, nitrogen-doped carbon cathode with good cycling and mechanical stability by 3D printing and pyrolysis of the zinc-based metal-organic framework ZIF-8. When incorporated into a zinc-ion hybrid capacitor, we achieved ...
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Enhanced Direct Degradation of Photogenerated Holes Induced by Dissolved O2 Chemisorbed on Oxygen-deficient Nano-TiO2Materials Today Sustainability (IF 7.244) Pub Date : 2023-03-21 ,DOI:10.1016/j.mtsust.2023.100391A. Shan, Yunfei Lu, Lin Cheng, Zebin Hou, Dege Xili, Yan Li, Juming Liu, Huiyan Ma, Jucai YangDue to the high electronegativity, dissolved O2 molecules can form strong chemisorption on oxygen-deficient nano-TiO2, which can alter the photocatalytic degradation process. Regarding this point, there is a lack of sufficient investigation so far, although there have been many reports on oxygen-deficient nano-TiO2. Here, we make the dissolved O2 adsorbed on the oxygen-deficient nano-TiO2 by simply ...
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Molecular Cloning and Expression Analysis of Lipoprotein Lipase (LPL) From Pampus ArgenteusThalassas: An International Journal of Marine Sciences (IF 0.951) Pub Date : 2023-03-20 ,DOI:10.1007/s41208-022-00475-9Shun Zhang, Mengdi Liu, Xiaojing Zhu, Chuangyuan Lin, Cheng Zhang, Xuemei Yan, Danli Wang, Shanliang XuTo investigate lipoprotein lipase (LPL) genes in lipid metabolism and their functional relationship, as well as the relationship between LPL mRNA expression and muscle and liver fat accumulation in different growth stages. Full-length cDNA sequences encoding LPL were obtained from Pampus argenteus by homologous clone and RACE methods. The sequence analysis showed that the complete cDNA sequence of ...
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Highly efficient and rapid generation of human pluripotent stem cells by chemical reprogrammingCell Stem Cell (IF 25.269) Pub Date : 2023-03-20 ,DOI:10.1016/j.stem.2023.02.008Shijia Liuyang, Guan Wang, Yanglu Wang, Huanjing He, Yulin Lyu, Lin Cheng, Zhihan Yang, Jingyang Guan, Yao Fu, Jialiang Zhu, Xinxing Zhong, Shicheng Sun, Cheng Li, Jinlin Wang, Hongkui DengWe recently demonstrated the chemical reprogramming of human somatic cells to pluripotent stem cells (hCiPSCs), which provides a robust approach for cell fate manipulation. However, the utility of this chemical approach is currently hampered by slow kinetics. Here, by screening for small molecule boosters and systematically optimizing the original condition, we have established a robust, chemically ...
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Eco-friendly and facile modified superhydrophobic melamine sponge by molybdenum sulfide for oil/water separationJournal of Applied Polymer Science (IF 3.057) Pub Date : 2023-03-18 ,DOI:10.1002/app.53875Lei Li, Rui Chen, Fengyu Wen, Yashu He, Lin Cheng, Jierun Ma, Jianxin MuOily wastewater has caused serious damage to the human health and ecological environment. It is urgent to develop novel materials for high performance oil/water separation. Porous melamine sponges (MS) are considered as an ideal matrix material for oil/water separation. Herein, molybdenum sulfide (MoS2) modified with tannic acid (TA) and octadecylamine (ODA) was attached to MS framework via a facile ...
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Adaptive colored noise multi-rate Kalman filter and its application in coseismic deformationsGeophysical Journal International (IF 3.352) Pub Date : 2023-03-18 ,DOI:10.1093/gji/ggad117Changxin Chen, Xu Lin, Wei Li, Lin Cheng, Hongyue Wang, Qingqing Zhang, Zhen WangSummary The accuracy and sampling rate of a coseismic displacement and velocity waveform can be improved by fusing Global Navigation Satellite System (GNSS) and strong motion (SM) sensor data with a multi-rate Kalman filter. However, many studies have shown that the noise in GNSS coseismic waveforms includes colored noise, and it is challenging to obtain proper GNSS and SM fusion results if the GNSS ...
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Theoretical studies of sliding ferroelectricity, magnetoelectric couplings, and piezo-multiferroicity in two-dimensional magnetic materialsChemical Physics Letters (IF 2.719) Pub Date : 2023-03-16 ,DOI:10.1016/j.cplett.2023.140430Tingting Zhong, Lin Cheng, Yangyang Ren, Menghao WuIt has been predicted that for a series of two-dimensional (2D) materials, their van der Waals bilayers may possess sliding ferroelectricity with vertical polarizations switchable via interlayer sliding. Such intriguing ferroelectricity has been recently experimentally confirmed in a series of nonmagnetic bilayer systems like BN, MoS2, etc., while magnetic bilayers remain unexplored in those reports ...
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Methodology for Capacity Credit Evaluation of Physical and Virtual Energy Storage in Decarbonized Power SystemarXiv - EE - Systems and Control Pub Date : 2023-03-16 ,DOI:arxiv-2303.09560Ning Qi, Peng Li, Lin Cheng, Ziyi Zhang, Wenrui Huang, Weiwei YangEnergy storage (ES) and virtual energy storage (VES) are key components to realizing power system decarbonization. Although ES and VES have been proven to deliver various types of grid services, little work has so far provided a systematical framework for quantifying their adequacy contribution and credible capacity value while incorporating human and market behavior. Therefore, this manuscript proposed ...
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Methodology for Capacity Credit Evaluation of Physical and Virtual Energy Storage in Decarbonized Power SystemarXiv - MATH - Probability Pub Date : 2023-03-16 ,DOI:arxiv-2303.09560Ning Qi, Peng Li, Lin Cheng, Ziyi Zhang, Wenrui Huang, Weiwei YangEnergy storage (ES) and virtual energy storage (VES) are key components to realizing power system decarbonization. Although ES and VES have been proven to deliver various types of grid services, little work has so far provided a systematical framework for quantifying their adequacy contribution and credible capacity value while incorporating human and market behavior. Therefore, this manuscript proposed ...
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Methodology for Capacity Credit Evaluation of Physical and Virtual Energy Storage in Decarbonized Power SystemarXiv - CS - Systems and Control Pub Date : 2023-03-16 ,DOI:arxiv-2303.09560Ning Qi, Peng Li, Lin Cheng, Ziyi Zhang, Wenrui Huang, Weiwei YangEnergy storage (ES) and virtual energy storage (VES) are key components to realizing power system decarbonization. Although ES and VES have been proven to deliver various types of grid services, little work has so far provided a systematical framework for quantifying their adequacy contribution and credible capacity value while incorporating human and market behavior. Therefore, this manuscript proposed ...
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Influencing Factors of the Specific Total Loss of Non-Oriented Electrical Steels Processed by Laser CuttingMetals (IF 2.695) Pub Date : 2023-03-15 ,DOI:10.3390/met13030595Qian Xiang, Lin Cheng, Kaiming Wu
Specific total loss is one of the most important evaluation indexes for the magnetic properties of non-oriented electrical steel sheets. The aim of this study is to investigate the influencing mechanisms of laser cutting parameters as well as the sample characteristics on the specific total loss of thin non-oriented electrical steel sheets processed by laser cutting using a machine learning method
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Base-mediated chalcogenoaminative annulation of 2-alkynylanilines for direct access to 3-sulfenyl/selenyl-1H-indolesOrganic & Biomolecular Chemistry (IF 3.89) Pub Date : 2023-03-15 ,DOI:10.1039/d3ob00279aWei-Ching Chen, Rekha Bai, Wan-Lin Cheng, Chun-Yu Peng, Daggula Mallikarjuna Reddy, Satpal Singh Badsara, Chin-Fa LeeAn efficient and transition metal-free synthesis of 3-sulfenyl/selenyl-1H-indoles via a base-assisted chalcogenoaminative annulation of 2-alkynyl aniline with disulfides/diselenides is described. A series of 2-alkynylanilines were found compatible with dichalcogenides in this transformation providing 3-sulfenyl/selenyl-1H-indoles in good to excellent yields. The presented methodology has the advantages ...
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Research on the Rate of Penetration Prediction Method Based on Stacking Ensemble LearningGeofluids (IF 2.006) Pub Date : 2023-3-14 ,DOI:10.1155/2023/6645604Yangfeng Ren, Baoping Lu, Shuangjin Zheng, Kai Bai, Lin Cheng, Hao Yan, Gan Wang
ROP is an important index to evaluate the efficiency of oil and gas drilling. In order to accurately predict the ROP of an oilfield in Xinjiang working area, a ROP prediction model based on the historical drilling data of this working area was established based on stacking ensemble learning. This model integrates the -nearest neighbor algorithm and support vector machine algorithm by stacking ensemble
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Damage Model and the Influence Factors of Mitigation Engineering against Glacial Debris Flow in the Parlung River Basin, SE Tibetan PlateauWater (IF 3.53) Pub Date : 2023-03-13 ,DOI:10.3390/w15061098Mingan Lin, Cheng Gong, Hai Huang, Dongxu Yang
Understanding the damage mechanism of glacial debris flow mitigation systems is crucial for the risk prevention and assessment of the 200 km traffic corridor in the Southeast of the Tibetan Plateau, where the Sichuan-Tibet railway and expressway have been planned. Based on the phenomena, position and residual efficiency of damaged engineering, our analysis of satellite imagery and field investigation
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Flexible and Highly Sensitive Sandwich-Structured PDMS with Silver Nanowires and Laser-Induced Graphene for Rapid Residue DetectionACS Applied Polymer Materials (IF 4.855) Pub Date : 2023-03-13 ,DOI:10.1021/acsapm.2c02011Lin Cheng, Jinchen Qian, Diqing Ruan, Guanzheng Chen, Jiayao Yang, Huaping Wu, Aiping LiuFlexible surface-enhanced Raman scattering (SERS) substrates offer advantages over traditional rigid substrates for efficient extraction of target molecules from complex surfaces, which is critical for technical applications ranging from pesticide residue analysis to environmental pollutant monitoring and forensic science detection. Herein, flexible sandwich-structured silver nanowires with laser-induced ...
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Quantitative Morphometry and Machine Learning Model to Explore Duodenal and Rectal Mucosal Tissue of Children with Environmental Enteric Dysfunction.The American Journal of Tropical Medicine and Hygiene (IF 3.707) Pub Date : 2023-03-13 ,DOI:10.4269/ajtmh.22-0063Sanjana Srivastava,Saman Siddiqui,Philip Fernandes,Muhammad Raghib,Saurav Sengupta,Zia Mujahid,Zubair Ahmed,Romana Idrees,Sheraz Ahmed,Fayaz Umrani,Najeeha Iqbal,Christopher Moskaluk,Shyam Raghavan,Lin Cheng,Sean Moore,Syed Asad Ali,Junaid Iqbal,Sana Syed
Environmental enteric dysfunction (EED) is a subclinical enteropathy prevalent in resource-limited settings, hypothesized to be a consequence of chronic exposure to environmental enteropathogens, resulting in malnutrition, growth failure, neurocognitive delays, and oral vaccine failure. This study explored the duodenal and colonic tissues of children with EED, celiac disease, and other enteropathies
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Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariantsNature Immunology (IF 31.25) Pub Date : 2023-03-13 ,DOI:10.1038/s41590-023-01449-6Bin Ju, Qi Zhang, Ziyi Wang, Zhen Qin Aw, Peng Chen, Bing Zhou, Ruoke Wang, Xiangyang Ge, Qining Lv, Lin Cheng, Rui Zhang, Yi Hao Wong, Huixin Chen, Haiyan Wang, Sisi Shan, Xuejiao Liao, Xuanling Shi, Lei Liu, Justin Jang Hann Chu, Xinquan Wang, Zheng Zhang, Linqi Zhang
The omicron variants of SARS-CoV-2 have substantial ability to escape infection- and vaccine-elicited antibody immunity. Here, we investigated the extent of such escape in nine convalescent patients infected with the wild-type SARS-CoV-2 during the first wave of the pandemic. Among the total of 476 monoclonal antibodies (mAbs) isolated from peripheral memory B cells, we identified seven mAbs with broad
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Immunotherapeutic potential of blinatumomab-secreting γ9δ2 T CellsTranslational Oncology (IF 4.803) Pub Date : 2023-03-12 ,DOI:10.1016/j.tranon.2023.101650Shang-Ju Wu, Chien-Ting Lin, Cheng Hao Liao, Chun-Ming Lin
Previous studies have explored the use of engineered blinatumomab-secreting autologous αβ T cells for CD19-targeted cancer therapy. To create a more flexible allogeneic delivery system, we utilized γ9δ2 T cells rather than αβ T cells in a similar application. First, we showed that γ9δ2 T cells could serve as effector cells for blinatumomab, and these effector memory cells could survive for at least
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Intelligent diagnostic scheme for lung cancer screening with Raman spectra data by tensor network machine learningarXiv - EE - Image and Video Processing Pub Date : 2023-03-11 ,DOI:arxiv-2303.06340Yu-Jia An, Sheng-Chen Bai, Lin Cheng, Xiao-Guang Li, Cheng-en Wang, Xiao-Dong Han, Gang Su, Shi-Ju Ran, Cong WangArtificial intelligence (AI) has brought tremendous impacts on biomedical sciences from academic researches to clinical applications, such as in biomarkers' detection and diagnosis, optimization of treatment, and identification of new therapeutic targets in drug discovery. However, the contemporary AI technologies, particularly deep machine learning (ML), severely suffer from non-interpretability, ...
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Intelligent diagnostic scheme for lung cancer screening with Raman spectra data by tensor network machine learningarXiv - CS - Machine Learning Pub Date : 2023-03-11 ,DOI:arxiv-2303.06340Yu-Jia An, Sheng-Chen Bai, Lin Cheng, Xiao-Guang Li, Cheng-en Wang, Xiao-Dong Han, Gang Su, Shi-Ju Ran, Cong WangArtificial intelligence (AI) has brought tremendous impacts on biomedical sciences from academic researches to clinical applications, such as in biomarkers' detection and diagnosis, optimization of treatment, and identification of new therapeutic targets in drug discovery. However, the contemporary AI technologies, particularly deep machine learning (ML), severely suffer from non-interpretability, ...
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The clinical characteristics of pediatric patients infected by SARS-CoV-2 Omicron variant and whole viral genome sequencing analysis.PLOS ONE (IF 3.752) Pub Date : 2023-03-10 ,DOI:10.1371/journal.pone.0282389Hin Fung Tsang,Allen Chi Shing Yu,Aldrin Kay Yuen Yim,Nana Jin,Yu On Wu,Hennie Yuk Lin Cheng,W L Cheung,Wai Ming Stanley Leung,Ka Wai Lam,Tin Nok Hung,Loiston Chan,Jiachi Chiou,Xiao Meng Pei,On Ying Angela Lee,William Chi Shing Cho,Sze Chuen Cesar Wong
Pediatric population was generally less affected clinically by SARS-CoV-2 infection. Few pediatric cases of COVID-19 have been reported compared to those reported in infected adults. However, a rapid increase in the hospitalization rate of SARS-CoV-2 infected pediatric patients was observed during Omicron variant dominated COVID-19 outbreak. In this study, we analyzed the B.1.1.529 (Omicron) genome
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Charging station location problem for maximizing the space-time-electricity accessibility: A Lagrangian relaxation-based decomposition schemeExpert Systems with Applications (IF 8.665) Pub Date : 2023-03-09 ,DOI:10.1016/j.eswa.2023.119801Maocan Song, Lin Cheng, Mingyang Du, Chao SunThe driving range of electric vehicles limits the accessibility of their users. Charging infrastructures such as charging stations are essential to improve the accessibility of electric vehicles. Existing charging station location studies neglected accessibility-based indicators in their optimization models. For the charging station location problem, this paper proposes a novel objective function that ...
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Portfolio optimization of generic energy storage-based virtual power plant under decision-dependent uncertaintiesJournal of Energy Storage (IF 8.907) Pub Date : 2023-03-09 ,DOI:10.1016/j.est.2023.107000Ning Qi, Lin Cheng, Hongtao Li, Yongliang Zhao, Hao TianDistributed energy resources (DERs) can be integrated into a smart and aggregated entity, namely a virtual power plant (VPP). This integration is beneficial to facilitate their flexibility utilization and optimally allocate their capacity to participate in competitive electricity markets. While various types of uncertainties exist in the market operation of VPP, such as the stochastic power of renewable ...
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Self-acupressure for symptom management in cancer patients: A systematic reviewJournal of Pain and Symptom Management (IF 5.576) Pub Date : 2023-03-09 ,DOI:10.1016/j.jpainsymman.2023.03.002Dr Hui-Lin Cheng, Dr Wing-Fai Yeung, Mr Hon Fat Wong, Miss Huen Ting Lo, Prof. Alex MolassiotisContext Acupressure is a popular non-pharmacological intervention that is increasingly proven to effectively alleviate symptoms in patients with cancer. However, the effects of self-acupressure on cancer symptom management are less clear. Objectives This systematic review is the first to summarize the current experimental evidence on self-acupressure for symptom management in cancer patients. Methods ...
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Ethanol production using the whole solid-state fermented sugarcane bagasse cultivated by Trichoderma reesei RUT-C30 supplemented with commercial cellulaseBiocatalysis and Agricultural Biotechnology Pub Date : 2023-03-08 ,DOI:10.1016/j.bcab.2023.102667Ching An Lin, Cheng Cheng, Li Wei Chen, C. Will Chen, Kow Jen DuanIndustrial ethanol production usually requires the costly use of commercial cellulase. Herein, we describe the direct use of cellulase produced by Trichoderma reesei RUT-C30 with sugarcane bagasse (SCB) as a substrate for the production of ethanol. The pretreated SCB supplemented with wheat bran (weight ratio of 4:1) was used for T. reesei cellulase production by solid-state fermentation. The cellulase ...
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High-Performance Phototransistor Memory with an Ultrahigh Memory Ratio Conferred Using Hydrogen-Bonded Supramolecular ElectretsACS Applied Materials & Interfaces (IF 10.383) Pub Date : 2023-03-08 ,DOI:10.1021/acsami.2c22501Yi-Hsun Weng, Yan-Cheng Lin, Jin-Chieh Ho, Wei-Chen Yang, Bi-Hsuan Lin, Cheng-Liang Liu, Wen-Chang ChenAs the research of photonic electronics thrives, the enhanced efficacy from an optic unit cell can considerably improve the performance of an optoelectronic device. In this regard, organic phototransistor memory with a fast programming/readout and a distinguished memory ratio produces an advantageous outlook to fulfill the demand for advanced applications. In this study, a hydrogen-bonded supramolecular ...
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