- 作 者: "bin hu"
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Dexmedetomidine postconditioning attenuates myocardial ischemia/reperfusion injury by activating the Nrf2/Sirt3/SOD2 signaling pathway in the rats.Redox report : communications in free radical research Pub Date : 2023-12-01 ,DOI:10.1080/13510002.2022.2158526Bin Hu,Tian Tian,Xin-Tao Li,Pei-Pei Hao,Wei-Chao Liu,Ying-Gui Chen,Tian-Yu Jiang,Pei-Shan Chen,Yi Cheng,Fu-Shan Xue
OBJECTIVES To observe the protective effects of dexmedetomidine (Dex) postconditioning on myocardial ischemia/reperfusion injury (IRI) and to explore its potential molecular mechanisms. METHODS One-hundred forty-seven male Sprague-Dawley rats were randomly divided into five groups receiving the different treatments: Sham, ischemia/reperfusion (I/R), Dex, Brusatol, Dex + Brusatol. By the in vivo rat
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Pre-clinical efficacy and safety pharmacology of PEGylated recombinant human endostatinCurrent Molecular Medicine (IF 2.616) Pub Date : 2023-03-31 ,DOI:10.2174/1566524023666230331091757Lifang guo, Bin Hu, linbin hua, Jing WangIntroduction: This study aimed to outline the pre-clinical efficacy and safety pharmacology of PEGylated recombinant human endostatin (M2ES) according to the requirements of new drug application. background: These studies aimed to outline the pre-clinical efficacy and safety pharmacology of PEGylated recombinant human endostatin (M2ES) according to the requirements of new drug application. Method: ...
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Disparate toxicity mechanisms of parabens with different alkyl chain length in freshwater biofilms: Ecological hazards associated with antibiotic resistomeScience of the Total Environment (IF 10.753) Pub Date : 2023-03-31 ,DOI:10.1016/j.scitotenv.2023.163168Sheng Liu, Peifang Wang, Chao Wang, Juan Chen, Xun Wang, Bin Hu, Xiaorong ShanAs emerging organic pollutants, parabens are of global concern because of their ubiquitous presence and adverse effects. However, few researchers have addressed the relationship between parabens' structural features and toxicity mechanisms. This study conducted theoretical calculations and laboratory exposure experiments to uncover the toxic effects and mechanisms of parabens with different alkyl chains ...
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Significance of nitrogen-fixing actinorhizal symbioses for restoration of depleted, degraded, and contaminated soilTrends in Plant Science (IF 22.012) Pub Date : 2023-03-30 ,DOI:10.1016/j.tplants.2023.03.005Bin Hu, Emmanouil Flemetakis, Zhenshan Liu, Robert Hänsch, Heinz RennenbergAtmospheric nitrogen (N2)-fixing legume trees are frequently used for the restoration of depleted, degraded, and contaminated soils. However, biological N2 fixation (BNF) can also be performed by so-called actinorhizal plants. Actinorhizal plants include a high diversity of woody species and therefore can be applied in a broad spectrum of environments. In contrast to N2-fixing legumes, the potential ...
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A performant and incremental algorithm for knowledge graph entity typingWorld Wide Web (IF 3.0) Pub Date : 2023-03-30 ,DOI:10.1007/s11280-023-01155-1Zepeng Li, Rikui Huang, Minyu Zhai, Zhenwen Zhang, Bin HuKnowledge Graph Entity Typing (KGET) is a subtask of knowledge graph completion, which aims at inferring missing entity types by utilizing existing type knowledge and triple knowledge of the knowledge graph. Previous knowledge graph embedding (KGE) algorithms infer entity types through trained entity embeddings. However, for new unseen entities, KGE models encounter obstacles in inferring their types ...
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Research on Supply Chain Optimization Considering Consumer Subsidy Mechanism in the Context of Carbon NeutralityEnergies (IF 2.702) Pub Date : 2023-03-30 ,DOI:10.3390/en16073147Zheng Liu, Wenzhuo Sun, Bin Hu, Chunjia Han, Petros Ieromonachou, Yuanjun Zhao, Jiazhuo ZhengWith the proposal of China’s “carbon peak, carbon neutral” strategy, the increasing awareness of low carbon production among consumers, and the government’s introduction of carbon trading mechanism and low carbon consumption subsidy policies, enterprises are facing good opportunities for development. However, how the government can reasonably formulate low carbon policies and how enterprises can implement ...
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Micro-mechanism insights into the adsorption of anionic dyes using quaternary ammonium-functionalised chitosan aerogelsCarbohydrate Polymers (IF 10.723) Pub Date : 2023-03-30 ,DOI:10.1016/j.carbpol.2023.120855Nan Du, Li-Yuan Huang, Yan-Shu Xiong, Run Tian, Jiang-Yu Yin, Dan-Yu Cao, Dong-Bin Hu, Hai-Qin Lu, Wen Li, Kai LiThe development of adsorbents with outstanding adsorption capacities, wide versatility, and excellent recyclability for the removal of organic dyes remains a challenge. In this study, a quaternised chitosan-based aerogel (QCSA) was fabricated via a facile method to effectively treat concomitant anionic dyes. Porous QCSA with high hydrophilicity, nontoxicity, excellent thermal stability, and sustainability ...
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Older but Stronger: Development of Platinum-Based Antitumor Agents and Research Advances in Tumor ImmunityInorganics Pub Date : 2023-03-30 ,DOI:10.3390/inorganics11040145Jianing Liu, Yi Cao, Bin Hu, Tao Li, Wei Zhang, Zhongze Zhang, Jinhua Gao, Hanjing Niu, Tengli Ding, Jinzhong Wu, Yutong Chen, Pengfei Zhang, Ruijuan Ma, Shihao Su, Chaojie Wang, Peng George Wang, Jing Ma, Songqiang XiePlatinum (Pt) drugs have developed rapidly in clinical applications because of their broad and highly effective antitumor effects. In recent years, with the rapid development of immunotherapy, Pt-based antitumor agents have gained new challenges and opportunities. Since the discovery of their pharmacological effects in immunotherapy and tumor microenvironment regulation, research into Pt drugs has ...
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An Improved Quantitative Analysis Method of Oscillation Mode for DFIG-Based Wind Power Base With LCC-HVDC Transmission Considering Frequency Coupling CharacteristicIEEE Access (IF 3.476) Pub Date : 2023-03-27 ,DOI:10.1109/access.2023.3261960Haipan Li, Heng Nian, Yiming Liu, Bin Hu, Yuming Liao, Meng Li
The line-commutated converter-based high-voltage direct-current (LCC-HVDC) transmission has become one of the main forms to deliver wind power in China. However, due to the connections of a large number of power electronic devices (PEDs), there emerges a risk of sub/super-synchronous oscillations in the DFIG-based wind power base with LCC-HVDC transmission. The existing multi-node system analysis methods
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A new shear creep damage model for rock masses after considering initial damage.PLOS ONE (IF 3.752) Pub Date : 2023-03-27 ,DOI:10.1371/journal.pone.0280793Bin Hu,Zeqi Wang,Jing Li,Erjian Wei,Liyao Ma,Ji Liu,Yu Xiaobo
For a long time, one of the important safety problems in open-pit mines is the stability of a large number of high slopes with gently inclined soft interlayer. Rock masses formed after long geological processes generally have some initial damage. Mining works also cause varying degrees of disturbance and damage to rock masses in the mining area during the mining process. This phenomenon means that
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Depressive semantic awareness from vlog facial and vocal streams via spatio-temporal transformerDigital Communications and Networks Pub Date : 2023-03-27 ,DOI:10.1016/j.dcan.2023.03.007Yongfeng Tao, Minqiang Yang, Yushan Wu, Kevin Lee, Adrienne Kline, Bin HuWith the rapid rise of information transmission via the Internet, efforts have been made to reduce network load to promote efficiency. One such application is semantic computing, which can extract and process semantic communication. Social media has enabled users to share their current emotions, opinions, and life events through their mobile devices. Notably, people suffering from mental health problems ...
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Necessary and Sufficient Condition for Organic Room-Temperature Phosphorescence from Host–Guest Doped Crystalline SystemsAdvanced Optical Materials (IF 10.05) Pub Date : 2023-03-27 ,DOI:10.1002/adom.202300289Catherine Demangeat, Yipeng Tang, Yixuan Dou, Sherrice Dale, Jakob Cielo, Eunkyoung Kim, Ha-Jin Lee, Anthony D'Aléo, Bin Hu, André-Jean AttiasControlling and predicting the long-lived room-temperature phosphorescence (RTP) from organic materials are the next challenges to address for the realization of new efficient organic RTP systems. Here, a new approach is developed to reach these objectives by considering host–guest doped crystals, as well-suited model systems in that they allow the comprehensive understanding of synergetic structural ...
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Alleviate Periodontitis and its Comorbidity Hypertension using A Nanoparticle-embedded Functional Hydrogel SystemAdvanced Healthcare Materials (IF 11.092) Pub Date : 2023-03-27 ,DOI:10.1002/adhm.202203337Shuo Xu, Bin Hu, Ting Dong, Bo-Yan Chen, Lin-Juan Du, Yu-Lin Li, Yan-Lin Chen, Guo-Cai Tian, Xue-Bing Bai, Ting Liu, Lu-Jun Zhou, Wu-Chang Zhang, Yan Liu, Qin-Feng Ding, Xue-Qing Zhang, Sheng-Zhong DuanPeriodontitis and hypertension often occur as comorbidities, which need to be treated at the same time. To resolve this issue, we proposed a controlled-release composite hydrogel approach with dual antibacterial and anti-inflammatory activities as a resolution to achieve the goal of co-treatment of comorbidities. Specifically, chitosan (CS) with inherent antibacterial properties was crosslinked with ...
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[Research on mechanisms of acupoint sensitization in gastric ulcer mice from perspective of dorsal root ganglion neuronal excitability].Zhen ci yan jiu = Acupuncture research Pub Date : 2023-03-25 ,DOI:10.13702/j.1000-0607.20220874Meng-Yang Long,Rui-Bin Hu,Zhi-Jun Diao,Yu-Wei Wu,Si-Meng Xue,Hai-Fa QiaoOBJECTIVE To investigate the relationship between acupoint sensitization on the body surface and neuronal intrinsic excitability of the medium- and small-size dorsal root ganglion (DRG) neurons from the perspective of ion channel kinetics in mice with gastric ulcer. METHODS Male C57BL/6J mice were randomly divided into control (n=32) and model groups (n=34). The gastric ulcer model was established ...
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A study on shipowner’s behavior intention to cross dam by integrating SEM-SD modelInternational Journal of Modeling, Simulation, and Scientific Computing Pub Date : 2023-03-24 ,DOI:10.1142/s1793962323500411Pan Gao, Siman Li, Xu Zhao, Bin HuAiming at the navigation congestion of water conservancy projects, the shipowner’s psychological mechanism and behavior evolution are embedded into the dynamic model, which explores the evolution law using empirical data. The structural equation model (SEM) was constructed based on four variables: Shipowner personality, waiting time perception, congestion charging experience and anchorage environmental ...
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In situ growth of LiMn2O4 on graphene oxide for efficient lithium extraction by capacitive deionizationJournal of Solid State Electrochemistry (IF 2.747) Pub Date : 2023-03-23 ,DOI:10.1007/s10008-023-05461-6Jinfeng Yang, Xiaohong Shang, Bin Hu, Boshuang Zhang, Yiwen Wang, Jianmao Yang, Jianyun LiuSelective extraction of lithium from brines has attracted significant interests with the rapid development of lithium battery industry. LiMn2O4 (LMO) is a typical lithium intercalation material with good redox activity and high theoretical adsorption capacity. However, the poor conductivity and stability of LMO lead to its performance deterioration. Here, LMO was in situ grown on graphene oxide flakes ...
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Realizing efficient asymmetric transmission using optical activity of ultrathin chiral metasurfaces for K-band applicationsMicrowave and Optical Technology Letters (IF 1.311) Pub Date : 2023-03-20 ,DOI:10.1002/mop.33674Aisha Bibi, M. Ismail Khan, Bin Hu, Imdad KhanAn elliptical chiral split-ring-resonator-based bilayer thin metasurface is introduced in this paper. The proposed metasurface realizes strong electromagnetic (EM) activity with asymmetric transmission in the K-band of the microwave regime. The efficiency is more than 80% over a range of frequencies from 18.6 to 20.8 GHz. Angular stability up to 60° makes the structure robust for practical applications ...
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A novel insight into the bimolecular concerted interaction in lignin pyrolysis: Tautomer-assisted hydrogen transfer mechanismChemical Engineering Journal (IF 16.744) Pub Date : 2023-03-20 ,DOI:10.1016/j.cej.2023.142513Wen-luan Xie, Bin Hu, Yuan-gu Xia, Guo-yong Song, Ji Liu, Ying Liu, Qiang LuBimolecular concerted interaction mechanism plays a vital role in lignin pyrolysis. According to the recently proposed hydroxyl-assisted hydrogen transfer (AHT) mechanism, the primary pyrolytic products can assist the hydrogen transfer process of linkage decomposition with their hydroxy groups acting as the mediator. Herein, the concerted interaction between two hydrogen transfer processes was further ...
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Clinical application of noninvasive prenatal testing in twin pregnancies: a single-centre experienceExpert Review of Molecular Diagnostics (IF 5.67) Pub Date : 2023-03-20 ,DOI:10.1080/14737159.2023.2193291Yanmei Luo, Bin Hu, Yang Long, Yan Pan, Lupin Jiang, Wei Xiong, Huanhuan Xu, Liang Xu, Dan WangAbstract Objectives To evaluate the clinical efficiency of non-invasive prenatal testing (NIPT) for fetal chromosomal aneuploidy screening in twin pregnancies. Methods A total of 1650 women with twin pregnancies were enrolled in the study, which underwent NIPT at the Southwest Hospital, Army Medical University, Chongqing, China from January 2013 to June 2022. Fetal karyotyping analysis was conducted ...
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A renewable platform based on the entropy-driven catalytic amplification and element labeling inductively coupled plasma mass spectrometry for microRNA analysisAnalytica Chimica Acta (IF 6.911) Pub Date : 2023-03-17 ,DOI:10.1016/j.aca.2023.341112Qi Kang, Beibei Chen, Man He, Bin HuThe element labeling inductively coupled plasma mass spectrometry (ICP-MS) strategy has been increasingly applied to the bioanalysis for various bio-targets. Herein, a renewable analysis platform with element labeling ICP-MS was firstly proposed for microRNA (miRNA) analysis. The analysis platform was established on the magnetic bead (MB) with entropy-driven catalytic (EDC) amplification. When the ...
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Infection of Trichinella spiralis Affects the Reproductive Capacity of ICR/CD-1 Male Mice by Reducing the Urine Pheromone Contents and Sperm QualityInternational Journal of Molecular Sciences (IF 6.208) Pub Date : 2023-03-17 ,DOI:10.3390/ijms24065731Gaojian Li, Tao Zhang, Bin Hu, Shuyi Han, Chen Xiang, Guohui Yuan, Hongxuan He
Female mice can discriminate the urinary odors of male mice due to their olfactory acuity. Parasitic infection or subclinical infection can decrease the odor attractiveness of male mice and finally lead to aversion or avoidance responses in odor selection for female mice. Trichinella spiralis is a kind of tissue-parasitizing nematode that causes trichinellosis, a zoonotic parasitic disease that spreads
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Evaluation of Cd2+ stress on Synechocystis sp. PCC6803 based on single-cell elemental accumulation and algal toxicological responseAquatic Toxicology (IF 5.202) Pub Date : 2023-03-17 ,DOI:10.1016/j.aquatox.2023.106499Yao Tao, Man He, Beibei Chen, Gang Ruan, Pingping Xu, Yixue Xia, Gaofei Song, Yonghong Bi, Bin HuWith the development of single cell analysis techniques, the concept of precision toxicology has been proposed in recent years. Due to the heterogeneity of cells, we need to perform toxicological assessments on individual cells. Microalgae, one kind of important primary producers, play as a major pathway by which heavy metals enter the food chain and thus accumulate/transfer to higher trophic levels ...
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The novel GATA1-interacting protein HES6 is an essential transcriptional cofactor for human erythropoiesisNucleic Acids Research (IF 19.16) Pub Date : 2023-03-17 ,DOI:10.1093/nar/gkad167Zi Wang, Pan Wang, Jieying Zhang, Han Gong, Xuchao Zhang, Jianhui Song, Ling Nie, Yuanliang Peng, Yanan Li, Hongling Peng, Yajuan Cui, Heng Li, Bin Hu, Jun Mi, Long Liang, Hong Liu, Ji Zhang, Mao Ye, Karina Yazdanbakhsh, Narla Mohandas, Xiuli An, Xu Han, Jing Liu
Normal erythropoiesis requires the precise regulation of gene expression patterns, and transcription cofactors play a vital role in this process. Deregulation of cofactors has emerged as a key mechanism contributing to erythroid disorders. Through gene expression profiling, we found HES6 as an abundant cofactor expressed at gene level during human erythropoiesis. HES6 physically interacted with GATA1
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Assessment on seasonal acidification and its controls in the Muping Marine Ranch, Yantai, ChinaMarine Pollution Bulletin (IF 7.001) Pub Date : 2023-03-15 ,DOI:10.1016/j.marpolbul.2023.114826Zhe Zhang, Yu-Bin HuOcean acidification has emerged as a major challenge affecting the development of the marine aquaculture. Seasonal variations of seawater pH and aragonite saturation (Ωarag) were investigated in the Muping Marine Ranch, Yantai. The results showed that the seasonal variations of pH and Ωarag were distinct. The temperature exerted opposite effects on pH and Ωarag and played a dominant role in pH variation ...
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CAIINET: Neural network based on contextual attention and information interaction mechanism for depression detectionDigital Signal Processing (IF 2.92) Pub Date : 2023-03-15 ,DOI:10.1016/j.dsp.2023.103986Li Zhou, Zhenyu Liu, Xiaoyan Yuan, Zixuan Shangguan, Yutong Li, Bin HuDepression is a globally widespread psychological disorder that has a serious impact on the physical and mental health of patients. Currently, depression detection methods based on physiological signals are widely used, but the limitation is that physiological signals are not easy to collect. With the rapid development of social media, vlogs posted by users not only reflect the current emotional state ...
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Enhancing proline turnover is the key physiological response of mature citrus leaves to fruitingScientia Horticulturae (IF 4.342) Pub Date : 2023-03-15 ,DOI:10.1016/j.scienta.2023.111979Huaye Xiong, Yayin Luo, Heinz Rennenberg, Jie Wang, Bin Hu, Huanyu Zhao, Xiaodong Tang, Yueqiang Zhang, Xiaojun ShiMature leaves are the central organs involved in carbon (C) and nitrogen (N) metabolism to support the growth and development of citrus trees. These metabolisms may be greatly altered by fruiting and N supply, which can be verified by a typical field phenomenon in which leaf chlorosis appeared on leaves of fruiting branches but not on leaves of adjacent nonfruiting branches on citrus trees. To elucidate ...
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Microphthalmia and anterior segment dysgenesis due to a double gene variant in GJA8 and CRYGCEuropean Journal of Ophthalmology (IF 1.922) Pub Date : 2023-03-14 ,DOI:10.1177/11206721231163611Lin Zhou, Ganghua Wang, Bin Hu, Hui Jiang, Fanwen Jiang, Zhuping XuIntroductionTo report a family with severe ocular disorder caused by double gene variants in causative genes of autosomal dominant cataracts, GJA8 and CRYGC.Case presentationA 5-month-old boy with ... ...
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Hyperspectral Video Tracker Based on Spectral Deviation Reduction and a Double Siamese NetworkRemote Sensing (IF 5.349) Pub Date : 2023-03-14 ,DOI:10.3390/rs15061579Zhe Zhang, Bin Hu, Mengyuan Wang, Pattathal V. Arun, Dong Zhao, Xuguang Zhu, Jianling Hu, Huan Li, Huixin Zhou, Kun Qian
The advent of hyperspectral cameras has popularized the study of hyperspectral video trackers. Although hyperspectral images can better distinguish the targets compared to their RGB counterparts, the occlusion and rotation of the target affect the effectiveness of the target. For instance, occlusion obscures the target, reducing the tracking accuracy and even causing tracking failure. In this regard
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Multiscale mapping of transcriptomic signatures for cardiotoxic drugsbioRxiv - Systems Biology Pub Date : 2023-03-14 ,DOI:10.1101/2021.11.02.466774Jens Hansen, Yuguang Xiong, Priyanka Dhanan, Bin Hu, Arjun Singh Yadaw, Gomathi Jayaraman, Rosa Tolentino, Yibang Chen, Kristin G. Beaumont, Robert Sebra, Dusica Vidovic, Stephan C. Schuerer, Joseph Goldfarb, James Gallo, Marc R. Birtwistle, Eric R Sobie, Evren U. Azeloglu, Seth Berger, Angel Chan, Christoph Schaniel, Nicole C. Dubois, Ravi Iyengar
Drug-induced gene expression profiles can identify potential mechanisms of toxicity. We focused on obtaining signatures for cardiotoxicity of FDA-approved tyrosine kinase inhibitors (TKIs) in human induced pluripotent stem cell-derived cardiomyocytes. Using bulk transcriptomics profiles, we applied singular value decomposition to identify drug-selective patterns in cell lines obtained from multiple
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Gravitational wave source clustering in the luminosity distance space with the presence of peculiar velocity and lensing errorsPhysics of the Dark Universe (IF 5.09) Pub Date : 2023-03-13 ,DOI:10.1016/j.dark.2023.101206Qing Yang, Bin Hu
GW number count can be used as a novel tracer of the large scale structure (LSS) in the luminosity distance space (LDS), just like galaxies in the redshift space. It is possible to obtain the DL−DA duality relation with clustering effect. However, the peculiar velocity dispersion error of the host galaxy and the foreground lensing magnification will contaminate the GW luminosity distance measurement
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