- 作 者: ( "zhiguo wu" OR "zhi-guo wu" )
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Effect of Artificial Liver Support Systems on Gut Microbiota in Patients with HBV-Related Acute-on-Chronic Liver FailurePathogens (IF 3.7) Pub Date : 2023-08-28 , DOI:10.3390/pathogens12091094Zhiying Song, Qiong Xie, Yao Zhou, Shufen Song, Zhen Gao, Yu Lan, Zhiguo Wu, Hongxin Cai, Dongshan Yu, Cuiyun Liu, Junrong Liang, Baogang Xie, Shuilin Sun
Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is a rare and severe form of end-stage liver disease with high mortality; gut microbes are strongly associated with the development of this severe liver disease but the exact association is unclear. Artificial liver support systems (ALSS) are clinically important in prolonging the waiting time for liver transplantation and in aiding
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A swift expanding trend of extracellular vesicles in spinal cord injury research: a bibliometric analysisJournal of Nanobiotechnology (IF 10.2) Pub Date : 2023-08-23 , DOI:10.1186/s12951-023-02051-6Fan Zhiguo, Wu Ji, Chen Shenyuan, Zhang Guoyou, Kai Chen, Qian Hui, Xu Wenrong, Xiao Zhai
Extracellular vesicles (EVs) in the field of spinal cord injury (SCI) have garnered significant attention for their potential applications in diagnosis and therapy. However, no bibliometric assessment has been conducted to evaluate the scientific progress in this area. A search of articles in Web of Science (WoS) from January 1, 1991, to May 1, 2023, yielded 359 papers that were analyzed using various
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Differences in the pharmacokinetics and steady-state blood concentrations of orally administered lenvatinib in adult and juvenile ratsFrontiers in Pharmacology (IF 5.6) Pub Date : 2023-07-28 , DOI:10.3389/fphar.2023.1140849Xiaoyue Du, Hongxin Cai, Nan Jin, Zhiguo Wu, Lele Wang, Zeyu Wang, Baogang Xie
Objective: The aim of this study was to compare the pharmacokinetics and steady-state serum concentrations of lenvatinib in adult and juvenile rats.Experimental study: An ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method was developed to quantify lenvatinib in the serum and liver of rats. Six juvenile and six adult rats in each group were orally administered with a single dose
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Screening and Validation Potential Therapeutic Marker of Early to Middle Stage ACLF Patients Treated by ALSSs.Clinical Laboratory Pub Date : 2023-06-01 , DOI:10.7754/clin.lab.2022.220835Zhen Gao,Guanlin Zhou,Weixin Wang,Wenlong Yang,Zhiguo Wu,Yunquan Cai,Lili Guo,Shuilin Sun,Baogang XieBACKGROUND Artificial liver support systems (ALSSs) are important approaches for treating acute-on-chronic liver failure (ACLF) patients. Few studies have investigated potential serum therapeutic markers of ACLF patients treated by ALSSs. METHODS Serum samples were obtained from 57 early to middle stage ACLF patients before and after ALSSs treatment and analyzed by metabonomics. The diagnostic values ...
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Characteristics and symptomatology of major depressive disorder with atypical features from symptom to syndromal levelJournal of Affective Disorders (IF 6.6) Pub Date : 2023-04-20 , DOI:10.1016/j.jad.2023.04.062Yifan Shi, Daihui Peng, Chen Zhang, David Mellor, Huaning Wang, Yiru Fang, Zhiguo WuObjective To explore clinical characteristics and symptomatology of major depressive disorder (MDD) with atypical features based on DSM criteria or only reversed vegetative symptoms. Method A total of 3187 patients who met DSM-IV TR criteria for MDD were enrolled. Demographics and symptomatology covering multiple symptom domains were assessed and compared between three groups of cases: those who met ...
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Large-scale long terminal repeat insertions produced a significant set of novel transcripts in cottonScience China Life Sciences Pub Date : 2023-04-17 , DOI:10.1007/s11427-022-2341-8Yan Yang, Xingpeng Wen, Zhiguo Wu, Kun Wang, Yuxian ZhuGenomic analysis has revealed that the 1,637-Mb Gossypium arboreum genome contains approximately 81% transposable elements (TEs), while only 57% of the 735-Mb G. raimondii genome is occupied by TEs. In this study, we investigated whether there were unknown transcripts associated with TE or TE fragments and, if so, how these new transcripts were evolved and regulated. As sequence depths increased from ...
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Additive manufacturing of three-dimensional graphene-based architectures and its application in environmental treatment: A reviewChemical Engineering Journal (IF 15.1) Pub Date : 2023-04-13 , DOI:10.1016/j.cej.2023.142943Huining Zhang, Xingmao Liu, Baixiang Wang, Zhongyu Shi, Zhiqiang Wei, Zhiguo Wu, Ying Zhu, Qi Guo, Xiaolong WangGraphene, as a new class of nanomaterials, demonstrates great potential in environmental treatment, while the shape of graphene powder state limits its use. Thus, the construction of large-volume three-dimensional graphene structures is of great significance for practical applications. In this paper, the commonly used methods for the preparation of three-dimensional structures nowadays are introduced ...
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Clinical Guideline (CANMAT 2016) Discordance of Medications for Patients with Major Depressive Disorder in ChinaNeuropsychiatric Disease and Treatment (IF 3.2) Pub Date : 2023-04-12 , DOI:10.2147/ndt.s401359Yuncheng Zhu, Zhiguo Wu, Dongmei Zhao, Xiaohui Wu, Ruoqiao He, Zuowei Wang, Daihui Peng, Yiru Fang
Objective: This survey aims to explore the current medical treatment of major depressive disorder (MDD) in China and match its degree with Canadian Network for Mood and Anxiety Treatments (CANMAT). Methods: A total of 3275 patients were recruited from 16 mental health centers and 16 general hospitals in China. Descriptive statistics presented the total number and percentage of drugs, as well as all
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SnS-RGO Hybrid Nanosheets as High Performance Flexible Photodetectors and Visible-Light PhotocatalystsJournal of Physics: Conference Series Pub Date : 2023-04-01 , DOI:10.1088/1742-6596/2468/1/012064Ang Li, Renfu Zhuo, Xiaoli Tang, Jun Wang, De Yan, Xuehu Men, Baisong Geng, Zhiguo Wu, Pengxun Yan, Guangàn Zhang
A straightforward solvothermal technique was used to create tin monosulfide (SnS) nanosheets that were reduced graphene oxide (RGO) bonded. On the folded RGO surface, it was discovered that the 2D SnS nanosheets had several layers that were evenly distributed. When exposed to visible light, a flexible photodetector made of PET substrate exhibits a 1.4 mA W−1 optical response, 3.5 × 107 Jones detection
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Selective degradation of ceftriaxone sodium by surface molecularly imprinted BiOCl/Bi3NbO7 heterojunction photocatalystSeparation and Purification Technology (IF 8.6) Pub Date : 2023-03-31 , DOI:10.1016/j.seppur.2023.123716Huining Zhang, Yankui Xiao, Yaoqing Peng, Lihong Tian, Yan Wang, Yuling Tang, Yang Cao, Zhiqiang Wei, Zhiguo Wu, Ying Zhu, Qi GuoBy using the surface molecular imprinting technique, BiOCl/Bi3NbO7 was used as the substrate photocatalyst and ceftriaxone sodium (CTRX) was used as the template. A molecularly imprinted photocatalyst with specific recognition and photocatalytic synergy for CTRX was synthesized. Due to the excellent photoelectric properties and the successful formation of CTRX-imprinted cavities on the imprinted layer ...
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The hepatoprotective effect of aspirin on carbon tetrachloride‑induced hepatic fibrosis via inhibition of TGFβ‑1 pathway and pro‑inflammatory cytokines IL‑1β and COX‑2 in rats.Experimental and Therapeutic Medicine (IF 2.7) Pub Date : 2023-03-31 , DOI:10.3892/etm.2023.11931Zhiguo Wu,Yuchan Wu,Weicheng Zhong,Qingmei Zhong,Shengfang Rao,Dongshan Yu,Xiaolu Luo,Fang Qiu,Zhiying Song,Di Jin,Maoxing Ai,Yu Lan,Gongchang Zhang,Shufeng Song,Baogang Xie,Shuilin Sun
Aspirin decreases liver fibrosis index and inflammation levels. However, the exact mechanism underlying the effects of aspirin are yet to be elucidated. The aim of the study was to investigate the potential protective effects of aspirin on carbon tetrachloride (CCl4)-induced hepatic fibrosis in Sprague-Dawley rats. Rats were divided into four groups, including healthy and CCl4 control and low-(aspirin
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Identification of potential serum biomarkers for congenital heart disease children with pulmonary arterial hypertension by metabonomicsBMC Cardiovascular Disorders (IF 2.1) Pub Date : 2023-03-29 , DOI:10.1186/s12872-023-03171-5Nan Jin, Mengjie Yu, Xiaoyue Du, Zhiguo Wu, Changlin Zhai, Haihua Pan, Jinping Gu, Baogang Xie
Pulmonary arterial hypertension is a common complication in patients with congenital heart disease. In the absence of early diagnosis and treatment, pediatric patients with PAH has a poor survival rate. Here, we explore serum biomarkers for distinguishing children with pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD) from CHD. Samples were analyzed by nuclear magnetic
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Thermal performance of novel form-stable disodium hydrogen phosphate dodecahydrate-based composite phase change materials for building thermal energy storageAdvanced Composites and Hybrid Materials (IF 11.806) Pub Date : 2023-03-24 , DOI:10.1007/s42114-023-00655-yPeng Lian, Ruihan Yan, Zhiguo Wu, Zhinbin Wang, Ying Chen, Li Zhang, Xinxin ShengInorganic hydrated salt phase change materials (PCMs) have received great attention due to their capabilities to reduce building energy consumption and improve building thermal comfort. In this work, a modified PCM (DHPD-STP) with a low supercooling degree was first prepared by using disodium hydrogen phosphate dodecahydrate (Na2HPO4·12H2O, DHPD) as the matrix and sodium thiosulfate pentahydrate (Na2S2O3·5H2O ...
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Effect of acupuncture on neuroinflammation in animal models of Alzheimer’s disease: A preclinical systematic review and meta-analysisFrontiers in Aging Neuroscience (IF 4.8) Pub Date : 2023-03-01 , DOI:10.3389/fnagi.2023.1110087Zhi-Guo Wu, Ying-Jie Huang, Tun-Yi Wang, Chu-Yu Deng, Zhi-Rui Xu, Chun-Zhi Tang
BackgroundDespite neuroinflammation being an important component of the pathology of Alzheimer’s disease (AD), effective therapies to alleviate neuroinflammation are still lacking. Many animal experiments in AD have found that acupuncture may ameliorate cognition by decreasing neuroinflammation and modulating cytokines, but its effects have not been systematically examined. We aimed to assess its efficacy
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Lubrication mechanisms of Nb-contained oxides characterizing tribochemistry of NiAl/Nb/Ag composites coatings revealed by the density functional theory (DFT) computationTribology International (IF 6.2) Pub Date : 2023-02-15 , DOI:10.1016/j.triboint.2023.108352Hongjian Guo, Pengxun Yan, Zhiguo Wu, Bo Li, Fuli Li, Jun Hu, Zhong ChenIn this work, the lubrication mechanisms of Nb-contained oxides were revealed by using the density functional theory (DFT) computation. Concretely, a series of Nb-contained oxides, e.g. Nb2O5, AgNbO3 and NiNb2O6 were generated through tribochemistry during the friction process of the fabricated NiAl/Nb/Ag coatings as the temperature was increased, and the friction coefficients decreased from 0.51 to ...
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Microstructure and tribo-mechanical properties of APS-sprayed NiAl/Cr2AlC composite coatings with various additions of self-made Cr2AlCSurface & Coatings Technology (IF 5.4) Pub Date : 2023-02-04 , DOI:10.1016/j.surfcoat.2023.129302Hongjian Guo, Bo Li, Pengxun Yan, Zhiguo Wu, Fuli Li, Zhiquan Wang, Zhiyuan LiuThe microstructures, tribo-mechanical properties of the fabricated NiAl/Cr2AlC composite coatings with various additions of self-made Cr2AlC were comparatively investigated. The results indicated that appropriate addition (10 wt%) of Cr2AlC could improve the microstructure, hardness, bending strength and tribological performance of the coatings. However, excessive addition of Cr2AlC led to the loose ...
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Microstructure and tribo-mechanical properties of APS-sprayed NiAl/Cr2AlC composite coatings with various additions of self-made Cr2AlCSurface and Coatings Technology Pub Date : 2023-02-04 , DOI:10.1016/j.surfcoat.2023.129302Hongjian Guo, Bo Li, Pengxun Yan, Zhiguo Wu, Fuli Li, Zhiquan Wang, Zhiyuan LiuThe microstructures, tribo-mechanical properties of the fabricated NiAl/Cr2AlC composite coatings with various additions of self-made Cr2AlC were comparatively investigated. The results indicated that appropriate addition (10 wt%) of Cr2AlC could improve the microstructure, hardness, bending strength and tribological performance of the coatings. However, excessive addition of Cr2AlC led to the loose ...
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Loss of furin site enhances SARS-CoV-2 spike protein pseudovirus infectionGene (IF 3.5) Pub Date : 2022-12-25 , DOI:10.1016/j.gene.2022.147144Zeng Wang, Kunhong Zhong, Guoqing Wang, Qizhong Lu, Hexian Li, Zhiguo Wu, Zongliang Zhang, Nian Yang, Meijun Zheng, Yuelong Wang, Chunlai Nie, Liangxue Zhou, Aiping TongBackground SARS-CoV-2 has a significant impact on healthcare systems all around the world. Due to its high pathogenicity, live SARS-CoV-2 must be handled under biosafety level 3 conditions. Pseudoviruses are useful virological tools because of their safety and versatility, but the low titer of these viruses remains a limitation for their more comprehensive applications. Method Here, we constructed ...
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Theoretical simulation and experimental perspective of refractive index-controlled silicon nanofilms for solar cell efficiency improvementSolar Energy Materials and Solar Cells (IF 6.9) Pub Date : 2022-12-11 , DOI:10.1016/j.solmat.2022.112145Ang Li, Zhiguo Wu, Renfu Zhuo, Tiaoe He, Yi Zhao, Pengxun Yan, Guangan ZhangThe excellent optical and electrical properties of silicon nanocrystals had attracted interest in the application of silicon-based solar cells. Optical coupling of nano silicon on the surface of solar cells was a valuable technology conducive to large-scale use, and the controlled optical properties of silicon nanofilms could better enhance the light absorption of solar cells. In this paper, we demonstrated ...
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Insights into the synthesis of monolithic and structured graphene bulks and its application for Cu2+ ions removal from aqueous solutionSeparation and Purification Technology (IF 8.6) Pub Date : 2022-12-08 , DOI:10.1016/j.seppur.2022.122847Huining Zhang, Zhongyu Shi, Xiaolong Wang, Xin Xu, Yuling Tang, Xingmao Liu, Lihong Tian, Yankui Xiao, Zhiguo Wu, Hongyu Wang, Yahong YangGraphene oxide (GO) was a promising adsorbent for the contaminants removal in the wastewater. However, the nanoscale GO with the properties of easy agglomeration and difficult to separate in the solution severely restricted its widespread practical application. Therefore, a monolithic and structured GO bulk was prepared by a 3D printing method and used as adsorbent for the removal of Cu2+ ions. The ...
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Preparation of Functionalized Graphene Oxide Composite Spheres and Removal of Cu2+ and Pb2+ from WastewaterWater, Air, & Soil Pollution (IF 2.9) Pub Date : 2022-12-03 , DOI:10.1007/s11270-022-05971-5Huining Zhang, Xingmao Liu, Lihong Tian, Yuling Tang, Zhongyu Shi, Yankui Xiao, Zhiguo Wu, Ying Zhu, Qi Guo, Zhangpu PengFunctionalized graphene oxide was an important candidate for removing heavy metal pollution. However, its difficult separation, low mechanical strength, and secondary pollution were restricted. In our study, polyvinyl alcohol/functionalized graphene oxide macroporous composite spheres (PVA/GO-SH) were prepared by wrapping sulfhydryl-functionalized graphene oxide (GO-SH) in polyvinyl alcohol (PVA) to ...
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Preparation of Functionalized Graphene Oxide Composite Spheres and Removal of Cu2+ and Pb2+ from WastewaterWater, Air, and Soil Pollution Pub Date : 2022-12-03 , DOI:10.1007/s11270-022-05971-5Huining Zhang, Xingmao Liu, Lihong Tian, Yuling Tang, Zhongyu Shi, Yankui Xiao, Zhiguo Wu, Ying Zhu, Qi Guo, Zhangpu PengFunctionalized graphene oxide was an important candidate for removing heavy metal pollution. However, its difficult separation, low mechanical strength, and secondary pollution were restricted. In our study, polyvinyl alcohol/functionalized graphene oxide macroporous composite spheres (PVA/GO-SH) were prepared by wrapping sulfhydryl-functionalized graphene oxide (GO-SH) in polyvinyl alcohol (PVA) to ...
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Adsorption of Sr(II) in aqueous solution by multilayer Titanium carbon nitrogen (Ti3CNTx) MXene: Box-Behnken modeling design and experimental studyJournal of Environmental Chemical Engineering (IF 7.7) Pub Date : 2022-11-21 , DOI:10.1016/j.jece.2022.109019Pengli Zhang, Jingguo Cao, Zongzheng Yang, Zhiguo Wu, Liya WuThe discharge of low-level radioactive wastewater from nuclear power accidents is an important source of radionuclides that enter and pollute the environment, such as 90Sr, which has a long half-life and is harmful. The effectiveness of multilayer Ti3CNTx MXene as a novel adsorbent for the removal of wastewater containing Sr2+ was explored. The synthesized multilayer Ti3CNTx MXene was characterized ...
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Comparison on the clinical features in patients with or without treatment-resistant depression: A National Survey on Symptomatology of Depression reportPsychiatry Research (IF 11.3) Pub Date : 2022-11-21 , DOI:10.1016/j.psychres.2022.114972Yingying Huang, Ping Sun, Zhiguo Wu, Xiaoyun Guo, Xiaohui Wu, Jun Chen, Lu Yang, Xiao Wu, Yiru Fang
Patients with treatment-resistant depression (TRD) have fewer treatment options and worse prognoses than those without TRD. Although the etiology or pathophysiology of TRD remains unclear, certain clinical variables have been found to be related to its severity and prognosis. Therefore, 1151 patients with recurrent depression were recruited from the National Survey on Symptomatology of Depression (NSSD)
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Corrigendum to “Sevoflurane up-regulates miR-7a to protect against ischemic brain injury in rats by down-regulating ATG7 and reducing neuronal autophagy” [Brain Res. Bull. 188 (2022) 214–222]Brain Research Bulletin (IF 3.8) Pub Date : 2022-11-14 , DOI:10.1016/j.brainresbull.2022.11.004Zhiguo Wu, Jian Tan, Lichang Lin, Wenting Zhang, Wanqiu Yuan
Abstract not available
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Changes of anhedonia and cognitive symptoms in first episode of depression and recurrent depression, an analysis of data from NSSDJournal of Affective Disorders (IF 6.6) Pub Date : 2022-10-20 , DOI:10.1016/j.jad.2022.10.015Juanjuan Ren, Zhiguo Wu, Daihui Peng, Jia Huang, Weiping Xia, Jingjing Xu, Chenglei Wang, Lvchun Cui, Yiru Fang, Chen ZhangBackground Anhedonia and cognitive impairment are core features of major depressive disorder (MDD), and are essential to the treatment and prognosis. Here, we aimed to investigate anhedonia and its cognitive correlates between first episode of depression (FED) and recurrent depression (RD), which was part of the National Survey on Symptomatology of Depression. Methods In this study, 1400 drug naïve ...
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Microstructures, mechanical properties and tribological behaviors of NiAl-based composite coatings with various addition of NbSurface & Coatings Technology (IF 5.4) Pub Date : 2022-10-18 , DOI:10.1016/j.surfcoat.2022.128977Hongjian Guo, Bo Li, Pengxun Yan, Zhiguo Wu, Fuli Li, Zhiyuan LiuThe microstructures, mechanical properties and tribological behaviors of the NiAl-based composite coatings with various addition of Nb were investigated. Particularly, the coatings registered a typically fine lamellar morphology and a dense microstructure, of which the microhardness increased with the Nb content increasing. Moreover, the coatings with various Nb contents registered different tribological ...
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Microstructures, mechanical properties and tribological behaviors of NiAl-based composite coatings with various addition of NbSurface and Coatings Technology Pub Date : 2022-10-18 , DOI:10.1016/j.surfcoat.2022.128977Hongjian Guo, Bo Li, Pengxun Yan, Zhiguo Wu, Fuli Li, Zhiyuan LiuThe microstructures, mechanical properties and tribological behaviors of the NiAl-based composite coatings with various addition of Nb were investigated. Particularly, the coatings registered a typically fine lamellar morphology and a dense microstructure, of which the microhardness increased with the Nb content increasing. Moreover, the coatings with various Nb contents registered different tribological ...
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Age of onset for major depressive disorder and its association with symptomatologyJournal of Affective Disorders (IF 6.6) Pub Date : 2022-09-29 , DOI:10.1016/j.jad.2022.09.096Lvchun Cui, Yun Wang, Lan Cao, Zhiguo Wu, Daihui Peng, Jun Chen, Haichen Yang, Han Rong, Tiebang Liu, Yiru FangBackground The age of onset (AOO) is a key factor for heterogeneity in major depressive disorder (MDD). Looking at the effect of AOO on symptomatology may improve clinical outcomes. This study aims to examine whether and how AOO affects symptomatology using a machine learning approach and latent profile analysis (LPA). Methods The study enrolled 915 participants diagnosed with MDD from eight hospitals ...
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CXCL11-armed oncolytic adenoviruses enhance CAR-T cell therapeutic efficacy and reprogram tumor microenvironment in glioblastomaMolecular Therapy (IF 12.4) Pub Date : 2022-09-02 , DOI:10.1016/j.ymthe.2022.08.021Guoqing Wang, Zongliang Zhang, Kunhong Zhong, Zeng Wang, Nian Yang, Xin Tang, Hexian Li, Qizhong Lu, Zhiguo Wu, Boyang Yuan, Meijun Zheng, Ping Cheng, Aiping Tong, Liangxue Zhou
Glioblastoma (GBM) is the most aggressive primary malignant brain cancer and urgently requires effective treatments. Chimeric antigen receptor T (CAR-T) cell therapy offers a potential treatment method, but it is often hindered by poor infiltration of CAR-T cells in tumors and highly immunosuppressive tumor microenvironment (TME). Here, we armed an oncolytic adenovirus (oAds) with a chemokine CXCL11
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